抗菌藥物亞抑菌濃度及其臨床意義
發(fā)布時間:2018-05-31 16:21
本文選題:亞抑菌濃度 + 最小選擇濃度。 參考:《中國感染與化療雜志》2017年05期
【摘要】:正隨著抗生素的廣泛應(yīng)用,細(xì)菌的耐藥性越益嚴(yán)重,而新抗生素的研發(fā)速度卻在明顯下降~([1-2]),這使得細(xì)菌耐藥,尤其是多重耐藥成為目前威脅人類健康嚴(yán)重的公共衛(wèi)生問題。為了抑制細(xì)菌耐藥的產(chǎn)生和發(fā)展,制定臨床合理的抗生素應(yīng)用策略,了解細(xì)菌耐藥產(chǎn)生機制就顯得尤為重要。隨著人們對細(xì)菌耐藥產(chǎn)生機制研究的進(jìn)展,臨床抗生素的應(yīng)用策略也在不斷改變,由基于最低抑菌濃度(MIC)
[Abstract]:In order to inhibit the production and development of bacterial drug resistance, it is very important to make rational antibiotic application strategy and understand the mechanism of bacterial drug resistance. With the development of research on the mechanism of drug resistance of bacteria, the application strategy of clinical antibiotics is changing, which is based on the minimum inhibitory concentration (MIC).
【作者單位】: 中國人民解放軍總醫(yī)院呼吸內(nèi)科;
【基金】:三亞市醫(yī)療衛(wèi)生科技創(chuàng)新項目(2016YW35) 解放軍總醫(yī)院臨床科研扶持基金項目(2014FC-TSYS-2002)
【分類號】:R96
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本文編號:1960509
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