【摘要】：目的研究雙腔起搏治療對(duì)急性下壁心梗合并三度房室傳導(dǎo)阻滯患者血清腦鈉肽、心肌肌鈣蛋白水平及心功能的影響。方法對(duì)比接受雙腔起搏治療的急性下壁梗死合并三度房室傳導(dǎo)阻滯患者(觀察組)、健康者(對(duì)照組)治療前后的血清腦鈉肽及心肌肌鈣蛋白指標(biāo)水平及觀察組患者治療前后的心功能指標(biāo)水平,分析患者治療后射血分?jǐn)?shù)(LVEF)與二尖瓣舒張?jiān)缙诘姆逯盗魉?E)/舒張晚期的峰值流速(A)(E/A)及Sra的相關(guān)性。結(jié)果在經(jīng)過治療后,觀察組的血清腦鈉肽及心肌肌鈣蛋白指標(biāo)水平雖然顯著降低,但仍高于對(duì)照組的水平,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組術(shù)后1個(gè)月的E/A、LVEF及Sra水平均分別顯著高于術(shù)前1d的水平,術(shù)后3個(gè)月除上述指標(biāo)的水平更加顯著增加后,LAEF水平較術(shù)前1d亦顯著增加,而LAVmin及LAVmax水平較術(shù)前1d顯著降低,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。LVEF與Sra水平呈正相關(guān)。結(jié)論雙腔起搏對(duì)急性下壁梗死合并三度房室傳導(dǎo)阻滯的患者進(jìn)行治療,可明顯改善其血清腦鈉肽和心肌肌鈣蛋白水平,改善心功能。
[Abstract]:Objective to study the effects of dual chamber pacing on serum brain natriuretic peptide (BNP), cardiac troponin level and cardiac function in patients with acute inferior myocardial infarction (AMI) complicated with three degree atrioventricular block (AVB). Methods the serum levels of brain natriuretic peptide and cardiac troponin in patients with acute inferior wall infarction complicated with three degree atrioventricular block (observation group) and healthy subjects (control group) before and after treatment were compared. The level of cardiac function before and after treatment, To analyze the correlation between ejection fraction (LVEF) and peak velocity of mitral valve (E) / late diastolic peak velocity (A) (E / A) and ra after treatment. Results after treatment, the levels of serum brain natriuretic peptide and cardiac troponin in the observation group were significantly decreased, but still higher than those in the control group (P0.05). In the observation group, the levels of E / Agna LVEF and Sra were significantly higher than those of 1 day after operation, and the levels of LAVmin and LAVmax decreased significantly at 3 months after operation as compared with 1 day before operation, and the level of Lef increased significantly at 3 months after operation compared with that on the 1st day before operation, and the levels of LAVmin and LAVmax were significantly lower in the observation group than in the first day before operation. The difference was statistically significant (P0.05). LVEF was positively correlated with Sra level. Conclusion Dual-chamber pacing can significantly improve the serum levels of brain natriuretic peptide and cardiac troponin and improve cardiac function in patients with acute inferior wall infarction complicated with three degree atrioventricular block.
【作者單位】： 河南省三門峽市中心醫(yī)院心臟重癥監(jiān)護(hù)室;
【分類號(hào)】：R541.7;R542.22

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