【摘要】：目的:本研究利用隨機對照,進行臨床觀察試驗,比較針刺結(jié)合壯醫(yī)藥線與常規(guī)西藥治療帶狀皰疹后遺神經(jīng)痛(postherpetic neuralgia,PHN)的臨床療效,為評價針刺結(jié)合壯醫(yī)藥線治療PHN臨床療效提供有效的依據(jù)。方法:本試驗研究將符合診斷標準、納入標準的60例PHN患者作為研究對象。將受試者隨機分為治療組和對照組,每組各30例。治療組采用針刺結(jié)合壯醫(yī)藥線點灸治療,對照組采用常規(guī)西藥治療:加巴噴丁膠囊、布洛芬緩釋膠囊、甲鈷胺片。兩組均為10天一個療程,連續(xù)治療三個療程。治療前、治療結(jié)束時分別進行評價,疼痛評分采用視覺模擬評分法(VAS),睡眠質(zhì)量采用匹茲堡睡眠指數(shù)(PSQI),情緒狀態(tài)采用漢密爾頓抑郁量表(HAMD)進行評價。并在結(jié)束1月后進行電話隨訪,記錄兩組VAS評分。結(jié)果:治療過程中,治療組有1例脫落病例,有效29例;對照組有1例脫落病例,有效29例。治療前兩組的性別、年齡構(gòu)成、病程長短、VAS評分、PSQI指數(shù)以及HAMD量表的比較,均無統(tǒng)計學意義(P0.05),表明兩組具有可比性。(1)治療組治療前后VAS比較,對照組組治療前后VAS比較,均有P0.01,表明兩種治療方案均能鎮(zhèn)痛。治療后兩組VAS的比較,P0.01,表明兩種治療方案鎮(zhèn)痛效果不同,治療組鎮(zhèn)痛效果更好。治療結(jié)束后1月進行隨訪,記錄VAS,兩組比較可得P0.01,治療組的遠期鎮(zhèn)痛效果優(yōu)于對照組。(2)治療組治療前后PSQI比較,對照組組治療前后PSQI比較,均有P0.01,表明兩種治療方案均能改善睡眠。治療后兩組PSQI的比較,P0.05,表明兩種治療方案改善睡眠效的果不同,治療組改善睡眠的效果更好。(3)治療組治療前后HAMD比較,對照組治療前后HAMD比較,均有P0.01,表明兩種治療方案均能改善情緒狀態(tài)。治療后兩組HAMD的比較,P0.01,表明兩種治療方案改善情緒狀態(tài)效果不同,治療組效果更好。(4)臨床療效比較。治療組:痊愈16例,顯效8例,有效3例,無效2例,總有效率93.10%;對照組:痊愈6例,顯效11例,有效7例,無效5例,總有效率82.76%。兩組療效比較,P0.01,說明治療組療效優(yōu)于對照組。結(jié)論:治療組治療PHN的療效優(yōu)于對照組。對PHN患者的疼痛、睡眠質(zhì)量以及情緒狀態(tài)的改善均優(yōu)于對照組。遠期鎮(zhèn)痛效果也優(yōu)于對照組�？芍槾探Y(jié)合壯醫(yī)藥線點灸治療PHN,療效確切,值得臨床推廣應用。
[Abstract]:Objective: to compare the clinical efficacy of acupuncture combined with Zhuang medicine line and conventional western medicine in the treatment of post-herpetic neuralgia (postherpetic neuralgia,PHN) with randomized controlled trials, and to compare the clinical efficacy of acupuncture combined with Zhuang medicine line in treating herpes zoster neuralgia (postherpetic neuralgia,PHN). To evaluate the clinical efficacy of acupuncture combined with Zhuang medicament thread in the treatment of PHN. Methods: 60 patients with PHN who met the diagnostic criteria were selected as subjects in this study. The subjects were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with acupuncture combined with Zhuang medicine thread moxibustion, while the control group was treated with conventional western medicine: gabapentin capsule, ibuprofen sustained-release capsule and mecobalamin tablet. Two groups are 10 days a course of treatment, continuous treatment of three courses. Before treatment, the patients were evaluated at the end of the treatment. The (VAS), sleep quality was evaluated by visual analogue scale (VAS), the Pittsburgh sleep index (PSQI),) was used to evaluate the emotional state, and the Hamilton depression scale (HAMD) was used to evaluate the emotional state. One month after the end of the telephone follow-up, the two groups of VAS scores were recorded. Results: in the course of treatment, there were 1 case of shedding and 29 cases of effective in the treatment group, and 1 case of shedding and 29 cases of effective in the control group. Before treatment, there was no significant difference in sex, age composition, duration of disease, VAS score, PSQI index and HAMD scale between the two groups (P0.05), which indicated that the two groups were comparable. (1) VAS in the treatment group was compared before and after treatment, and there was no significant difference between the two groups before and after treatment (P0.05). The comparison of VAS before and after treatment in the control group showed P 0.01, indicating that both of the two treatment schemes were able to relieve pain. The comparison of VAS between the two groups after treatment, P 0.01, showed that the analgesic effect of the two treatment schemes was different, and the analgesic effect of the treatment group was better than that of the control group. The long-term analgesic effect of the treatment group was better than that of the control group. (2) the comparison of PSQI before and after treatment in the treatment group and the PSQI comparison before and after treatment in the control group showed that there was P 0.01 in both the VAS, group and the control group. These results suggest that both treatments can improve sleep. The comparison of PSQI, P0.05 between the two groups after treatment showed that the effects of the two treatment schemes on improving sleep were different, and that the effect of improving sleep in the treatment group was better than that in the treatment group. (3) the comparison of HAMD before and after treatment in the treatment group and the HAMD comparison before and after treatment in the control group showed that both of them had P0.01, The results showed that both treatments could improve emotional state. The comparison of HAMD, P0.01 between the two groups after treatment showed that the two therapeutic schemes had different effects on improving emotional state, and the effect of the treatment group was better. (4) the clinical curative effect was compared. In the treatment group, 16 cases were cured, 8 cases were markedly effective, 3 cases were effective, 2 cases were ineffective, and the total effective rate was 93.10%, while in the control group, 6 cases were cured, 11 cases were markedly effective, 7 cases were effective, 5 cases were ineffective, and the total effective rate was 82.76%. Comparison of two groups, P 0.01, showed that the therapeutic effect of the treatment group was better than that of the control group. Conclusion: the therapeutic effect of PHN in the treatment group is better than that in the control group. The improvement of pain, sleep quality and emotional state of PHN patients was better than that of control group. The long-term analgesic effect was better than that of the control group. It is known that acupuncture combined with Zhuang medicine thread moxibustion is effective in the treatment of PHN, and it is worthy of clinical popularization and application.
【學位授予單位】：廣西中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R246.7

【參考文獻】

相關期刊論文 前10條

1 魏常學;;藥線點灸聯(lián)合中藥外洗治療急性濕疹的臨床效果觀察[J];臨床醫(yī)學研究與實踐;2016年10期

2 魏常學;;穴位埋線結(jié)合電針及中藥治療帶狀皰疹后遺神經(jīng)痛的臨床價值分析[J];臨床醫(yī)學研究與實踐;2016年09期

3 張立欣;張金芳;邊莉;;火針治療帶狀皰疹后遺神經(jīng)痛療效分析[J];亞太傳統(tǒng)醫(yī)藥;2016年11期

4 閆s，

本文編號：2444973