【摘要】：目的:運(yùn)用中醫(yī)傳承輔助平臺(tái)軟件挖掘分析近5年來(lái)中醫(yī)藥治療強(qiáng)直性脊柱炎及骨質(zhì)疏松的用藥規(guī)律。方法:篩選治療強(qiáng)直性脊柱炎的方劑121首,骨質(zhì)疏松癥的方劑118首,采用關(guān)聯(lián)規(guī)則apriori算法、復(fù)雜系統(tǒng)熵聚類等無(wú)監(jiān)督數(shù)據(jù)挖掘方法,分析處方中各種藥物的使用頻次及藥物之間的關(guān)聯(lián)規(guī)則,挖掘藥物核心組合并進(jìn)行比較。結(jié)果:中醫(yī)藥治療強(qiáng)直性脊柱炎和骨質(zhì)疏松癥用藥規(guī)律相似,均以補(bǔ)腎活血通絡(luò)為治則治法,但用藥側(cè)重點(diǎn)存在差異,即強(qiáng)直性脊柱炎的治療以補(bǔ)腎與活血通絡(luò)止痛并重,而骨質(zhì)疏松癥的治療以補(bǔ)腎為主佐以活血。結(jié)論:中醫(yī)藥治療強(qiáng)直性脊柱炎及骨質(zhì)疏松癥的用藥規(guī)律存在差異,前者以補(bǔ)腎藥與活血止痛藥并重,后者以補(bǔ)腎藥為主。
[Abstract]:Objective: to analyze the treatment of ankylosing spondylitis and osteoporosis by traditional Chinese medicine (TCM) in recent 5 years. Methods: 121 prescriptions for treatment of ankylosing spondylitis and 118 prescriptions for osteoporosis were selected. Unsupervised data mining methods such as association rule apriori algorithm and complex system entropy clustering were used. The frequency of drug use and the association rules between drugs were analyzed, and the core combinations of drugs were excavated and compared. Results: the treatment of ankylosing spondylitis and osteoporosis by traditional Chinese medicine was similar, both of them were treated by tonifying kidney and activating blood circulation and collaterals, but there were some differences in drug use, that is to say, the treatment of ankylosing spondylitis was based on reinforcing kidney and activating blood circulation and regulating collaterals to relieve pain. The treatment of osteoporosis is mainly to tonify the kidney and promote blood circulation. Conclusion: there are differences in the treatment of ankylosing spondylitis and osteoporosis between traditional Chinese medicine and osteoporosis. The former focuses on tonifying the kidney and activating blood circulation to relieve pain, while the latter is mainly used to tonify the kidney.
【作者單位】： 廣州中醫(yī)藥大學(xué);廣東省第二中醫(yī)院;
【分類號(hào)】：R259

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