本文選題：中風 + 氣虛血瘀證��； 參考：《中醫(yī)學報》2017年05期

【摘要】：目的:觀察通脈舒絡膠囊聯(lián)合康復療法治療氣虛血瘀型缺血性中風的臨床療效。方法:選取114例氣虛血瘀型缺血性中風患者,隨機分為對照組和觀察組,各57例。對照組采用常規(guī)藥物治療和康復治療,觀察組在此基礎上聯(lián)合通脈舒絡膠囊,療程為28 d,對比兩組患者療效及中醫(yī)證候(主癥、兼癥、舌脈)改善情況,并采用美國國立衛(wèi)生研究院卒中量表(national institute of health stroke scale,NIHSS)、Fugl-Meyer(FMA)量表、日常生活活動能力量表(Barthel指數)等評價患者治療前后功能狀態(tài)改變情況,采用凝血酶原時間(prothrombin time,PT)、活化部分凝血酶時間(activated partial thromboplastin time,APTT)、血小板聚集率(platelet aggregation rate,PAR)、D-二聚體(D-Dimer,D-D)血清含量等評價患者治療前后凝血功能改善情況。結果:觀察組有效率為75.44%,明顯優(yōu)于對照組的56.14%,差異有統(tǒng)計學意義(P0.05);兩組中醫(yī)證候主癥評分、NIHSS、FMA、Barthel指數、PT、APTT、PAR、D-D等治療前后比較,差異均有統(tǒng)計學意義(P0.05)。觀察組兼癥評分、舌脈評分均明顯低于治療前,差異有統(tǒng)計學意義(P0.05),對照組兼癥評分、舌脈評分治療前后比較,差異無統(tǒng)計學意義(P0.05)。治療后觀察組主癥評分、兼癥評分、舌脈評分、NIHSS評分、PAR、D-D等均明顯低于對照組,FMA、Barthel評分、PT、APTT等均明顯高于對照組,差異均有統(tǒng)計學意義(P0.05)。結論:通脈舒絡膠囊聯(lián)合康復療法用于氣虛血瘀型缺血性中風患者,可改善患者血液高凝狀態(tài),減少神經缺損,提高肢體功能及日常生活能力,減輕臨床癥狀,療效確切。
[Abstract]:Objective: to observe the clinical effect of Tongmaisuoluo capsule combined with rehabilitation therapy on ischemic stroke of qi deficiency and blood stasis type. Methods: 114 patients with ischemic stroke of qi deficiency and blood stasis type were randomly divided into control group and observation group, 57 cases each. The control group was treated with routine medicine and rehabilitation, and the observation group was treated with Tongmaisuoluo capsule for 28 days. The curative effect of the two groups and the improvement of TCM syndromes (main symptoms, syndromes, tongue veins) were compared. The National institute of health stroke scale (NIH) and the activity of Daily living scale (ADL) were used to evaluate the changes of functional status before and after treatment. Prothrombin time (PT), activated partial thrombin time (partial thromboplastin), activated partial thromboplastin time (APTTT), platelet aggregation rate (platelet aggregation rate) and serum content of D-dimer D-Dimer (D-Dimer) D-D) were used to evaluate the improvement of coagulation function before and after treatment. Results: the effective rate of the observation group was 75.44, which was significantly better than that of the control group (56.14), the difference was statistically significant (P0.05), and the difference between the two groups was statistically significant before and after treatment with NIHSS-FMA-Barthel index, PTAPTTTT-PARD-D and so on. The scores of syndromes and tongue veins in the observation group were significantly lower than those before treatment, and the difference was statistically significant (P 0.05). There was no significant difference between the control group and the control group before and after treatment (P 0.05). After treatment, the scores of main symptoms, syndromes, tongue vein and NIHSS scores were significantly lower in the observation group than those in the control group (P 0.05), and were significantly lower than those in the control group (P 0.05). Conclusion: Tongmaisuluo capsule combined with rehabilitation therapy can improve blood hypercoagulability, reduce nerve defect, improve limb function and daily life ability, and alleviate clinical symptoms in patients with ischemic apoplexy of Qi deficiency and blood stasis type.
【作者單位】： 河南中醫(yī)藥大學第一附屬醫(yī)院;
【基金】：國家中醫(yī)藥管理局全國名老中醫(yī)藥專家傳承工作室建設項目{豫中醫(yī)業(yè)函[2014]86號} 河南省高等學校重點科研項目(16A320074)
【分類號】：R255.2

【相似文獻】

相關期刊論文 前5條

1 郭會軍;舒絡膠囊治療急性腦梗塞的臨床研究[J];中國中醫(yī)基礎醫(yī)學雜志;2005年10期

2 馬云枝;沈曉明;楊澤鋒;;通脈舒絡膠囊結合針刺治療血管性癡呆臨床研究[J];中國中醫(yī)急癥;2013年03期

3 馬云枝;劉政偉;沈曉明;;通脈舒絡膠囊聯(lián)合針刺治療氣虛血瘀型腦梗死64例[J];中醫(yī)研究;2014年04期

4 馬云枝;劉政偉;沈曉明;;通脈舒絡膠囊結合針灸治療腦卒中后尿失禁患者68例臨床觀察[J];時珍國醫(yī)國藥;2014年05期

5 ;[J];;年期

，

本文編號：2019623