本文選題：薛生白 + 濕熱病篇　； 參考：《河南中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:通過對(duì)薛生白《濕熱病篇》篇中藥物、方劑的相關(guān)研究,以探討薛氏治療濕熱病證的用藥配伍規(guī)律。方法:選取權(quán)威版本(包括底本和校本),然后對(duì)薛氏《濕熱病篇》所涉及藥物及方劑進(jìn)行參校核對(duì),以確保本論文研究初始資料的客觀性和準(zhǔn)確性,此為一。其二,依據(jù)參校結(jié)果,建立相對(duì)應(yīng)Word文檔析出該篇方劑(按條文依序命名)、藥物。其三,根據(jù)篩選標(biāo)準(zhǔn),對(duì)條文涉及到的具體藥物及方劑各自創(chuàng)建內(nèi)容為藥物“功效”、“四氣”、“五味”、“氣味”、“歸經(jīng)”的Excel信息表。其四,以創(chuàng)建的信息表為依據(jù),參照排除標(biāo)準(zhǔn)對(duì)該篇方劑數(shù)目、藥味味次數(shù)、藥味總數(shù)次、藥物頻次、功效頻次、四性頻次、五味頻次、歸經(jīng)頻次等指標(biāo)給予統(tǒng)計(jì)分析。最后,采用IBM公司開發(fā)的SPSS20.0統(tǒng)計(jì)軟件對(duì)符合納入標(biāo)準(zhǔn)的該篇藥物、方劑的各個(gè)指標(biāo)給予統(tǒng)計(jì)描述和相關(guān)聚類分析,以探討薛氏用藥配伍規(guī)律。結(jié)果:1.薛氏該篇符合納入標(biāo)準(zhǔn)的方劑有36首、藥物味數(shù)(不計(jì)重復(fù)次數(shù))有111味次,藥物總頻次為240藥次。2.其中高頻藥物是:甘草、滑石、菖蒲、生地、蒼術(shù)、茯苓、半夏、金銀花、人參、藿香、厚樸、犀角、連翹、陳皮、草果等。3.高頻藥物功效是:利水滲濕、芳香化濕、補(bǔ)氣、清熱涼血、祛痰止咳平喘、辛涼解表、清熱解毒、理氣、清熱瀉火、補(bǔ)血等。對(duì)其以“藥物功效”指標(biāo)聚類,聚類點(diǎn)為12時(shí)該篇方劑易聚為11類,各類方大抵以祛濕清熱為主,兼以理氣、補(bǔ)氣等。4.該篇藥物歸經(jīng)頻次位居前6的經(jīng)別是:胃經(jīng)、肺經(jīng)、脾經(jīng)、肝經(jīng)、心經(jīng)、腎經(jīng),說明濕熱病變中心多在中焦脾胃,可蒙上流下波及上下二焦。對(duì)其以“藥物歸經(jīng)”指標(biāo)聚類,聚類點(diǎn)為6時(shí)方劑易聚為8類,各類方歸經(jīng)或脾胃、或肺胃、或心肝、或心腎各有偏移。5.藥物四性以寒涼為主、溫?zé)釣檩o,寒溫并用;方劑以“藥物四性”指標(biāo)聚類,聚類點(diǎn)為6時(shí)該篇方劑易聚為7類,方劑內(nèi)藥物寒溫構(gòu)成有所差異。6.用藥以甘味、苦味、辛味、淡味為主,咸味、酸澀味次之;對(duì)該篇方劑以“藥物五味”為指標(biāo)對(duì)其聚類,聚類點(diǎn)為7時(shí)該篇方劑易聚為8類,各類方劑五味比重有所不同。結(jié)論:通過對(duì)薛生白《濕熱病篇》全篇方藥統(tǒng)計(jì)得出薛氏方藥運(yùn)用規(guī)律是:濕熱病證病因?yàn)闈駸岷闲?病變中心多在脾胃,主要病機(jī)為內(nèi)外相引;用藥多歸胃、肺、肝經(jīng)、脾經(jīng);治療原則以祛濕清熱為主,兼以顧護(hù)正氣;選用藥味以寒涼為主、溫?zé)釣檩o,寒溫并用;注重立法用藥,用藥精當(dāng),藥盡其用,也頗重視氣味配伍。而通過對(duì)其所用藥物配伍的管測(cè)探討可知,薛氏對(duì)濕熱病證研究可謂見解頗深、體悟獨(dú)到,彰顯了薛氏作為一代溫病大家的風(fēng)采。薛氏此篇是對(duì)溫病學(xué)理論的進(jìn)一步發(fā)展和有益補(bǔ)充,對(duì)后世醫(yī)家比如吳鞠通獨(dú)立濕溫病名和完善規(guī)范診治產(chǎn)生了較為深遠(yuǎn)影響,具有很高的學(xué)術(shù)價(jià)值。此外,現(xiàn)在臨床上常見濕熱為患疾病,無論外感抑或內(nèi)傷雜病,涉及全身各個(gè)系統(tǒng),與它癥比如陰虛、寒濕等癥難于鑒別,且治療起來亦頗為棘手,故也很具有臨床研究必要。因此繼續(xù)深入研習(xí)薛生白《濕熱病篇》有著現(xiàn)實(shí)和長(zhǎng)遠(yuǎn)的意義,值得我們進(jìn)一步好好探究。
[Abstract]:Objective: through the study of medicine and prescription in Xue Shengbai's "dampness and heat" article, to explore the compatibility of schaeh's treatment of damp heat syndrome. Methods: select the authoritative version (including the base and school edition), and then check the drugs and prescriptions involved in Xue's "dampness fever", so as to ensure the objectivity of the initial data in this paper. And this is one. Secondly, according to the results of the school, we set up the prescription of the prescription (named according to the provisions) and the medicine. Thirdly, according to the screening standard, the specific drugs and prescriptions involved in the provisions are created for the drug "efficacy", "four Qi", "five flavors", "smell", "return to the classics" of the Excel information table. Fourthly, based on the information table created, the number of prescriptions, the number of drug flavors, the number of drug flavour, the frequency of drug, the frequency of efficacy, the frequency of four sex, the frequency of five flavors, and the frequency of the classics were analyzed according to the exclusion criteria. Finally, the SPSS20.0 statistical software developed by IBM company was used for the drug, which was in conformity with the standard. Each index was given a statistical description and a correlation cluster analysis to explore the rules of the compatibility of Xue's medicine. Results 1. schroech was 36 of the prescriptions in accordance with the standard. The number of drug flavors (without repetition) was 111 times, and the total frequency of the drug was 240 times.2.. The high frequency drugs were licorice, talcum, calamus, land, Atractylodes, Poria, pinellia, and silver. Flowers, ginseng, huoxien, cortex magnolia, rhinoceros horn, forsythia, tangerine, grass fruit and other.3. high frequency drug effects are: water infiltration, aromatic humid, Qi, dispelling phlegm and cooling blood, dispelling phlegm and relieving cough, relieving cough, relieving heat, clearing heat and detoxifying, Qi, clearing heat and reducing fire, enriching blood and so on. It is mainly to remove the heat and remove the heat, and to make Qi, Qi and other.4. in the first 6 of the classics: stomach meridian, lung meridian, spleen meridian, liver meridian, heart meridian, kidney meridian, indicating that the center of damp and hot lesions is mostly in the middle of the spleen and stomach, and can be covered up and down in the upper and lower two coke. The four sex of.5. drugs, either in the spleen or stomach, or in the stomach, or in the heart and the heart, or in the heart and kidney, are mainly cold, cold and cold. The prescription is clustered with "drug four", and when the cluster point is 6, the prescription of the prescription is 7. The composition of the cold temperature in the prescription is different from that of the bitter taste, the bitterness, the bitter taste, the light taste, the salty taste and the sour taste. The prescription of this prescription was clustered with "five flavour of medicine" as the index. When the cluster point was 7, the prescription of the prescription was 8 and the proportion of all kinds of prescriptions was different. Conclusion: through the statistics of Xue Shengbai < damp heat disease > the whole prescription of prescription medicine, the rule of applying Xue's prescription is that damp heat syndrome is due to damp heat and heat, and the center of the lesion is mostly in the spleen and stomach. The main pathogenesis is internal and external induction; the medicine is mainly stomach, lung, liver, and spleen meridian; the treatment principle is mainly to dispel the damp and clear heat, and to protect the positive gas; the drug taste is cold and cold mainly, the warm heat is supplemented, the cold temperature is used. The study of the syndrome of damp and heat disease is very deep, and its unique understanding shows the elegant demeanor of Xue Shi as a generation of febrile diseases. This article is a further development and beneficial supplement to the theory of febrile diseases. It has a profound influence on the later physicians, such as Wu Jutong's name and the perfect standard of diagnosis and treatment, and has a high academic value. In addition, the clinical common humid and heat for the disease, whether external or internal injury, involving the whole body system, and its disease such as yin deficiency, cold and dampness are difficult to identify, and the treatment is quite difficult, so it is also very necessary for clinical research. Therefore, it is worth continuing to study Xue Shengbai's "dampness and fever", which has practical and long-term significance. Let's further explore.

【學(xué)位授予單位】：河南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R254

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