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  本文選題：盆腔炎性疾病后遺癥 + 清熱消痛湯�。� 參考：《福建中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:觀察清熱消痛湯聯合康婦消炎栓治療濕熱瘀結型盆腔炎性疾病后遺癥的臨床療效,客觀地評價本方在改善患者臨床癥狀、體征方面的有效性,提高治愈率及減少復發(fā)率的可能性。方法:采用隨機分組的方法將60例辨證為濕熱瘀結型盆腔炎性疾病后遺癥的患者隨機分為A組(治療組:清熱消痛湯聯合康婦消炎栓組)、B組(對照組:婦科千金片聯合康婦消炎栓組),每組各30例。通過觀察患者用藥前和用藥后1個療程、2個療程、3個療程以及停藥后1個月的臨床變化,并進行統(tǒng)計學分析,對其臨床療效進行評價。結果:1.綜合療效比較:治療1個療程后,治療組的總有效率80%,對照組的總有效率73.33%,兩組組間比較無顯著差異(P0.05),說明兩組均能改善患者臨床癥狀,且療效相當;治療2個療程后,治療組的總有效率90.00%對照組的總有效率76.67%,兩組組間比較有差異(P0.05),說明治療組綜合療效優(yōu)于對照組;治療3個療程后,治療組的總有效率93.33%,對照組的總有效率80.00%,兩組組間比較有差異(P0.05),說明治療組的綜合療效仍優(yōu)于對照組;停藥1個月后,治療組的總有效率90.00%,對照組的總有效率73.33%,有統(tǒng)計學意義,說明治療組的綜合療效仍高于對照組。2.中醫(yī)證候比較:治療3個療程后,治療組的中醫(yī)證候總有效率96.67%,對照組的中醫(yī)證候總有效率83.33%,兩組組間比較差異有統(tǒng)計學意義(P0.05),說明治療組的中醫(yī)證候療效的改善優(yōu)于對照組。3.局部體征比較:治療3個療程后兩組患者局部體征積分對比,差異有統(tǒng)計學意義(P0.05),說明治療組的體征改善優(yōu)于對照組。4.超聲比較:治療3個療程后比較盆腔超聲檢查結果(盆腔積液和附件區(qū)包塊),無統(tǒng)計學差異(P0.05),說明2組均能減少盆腔積液和縮小附件區(qū)包塊,且療效相當。5.可行性分析:兩組治療前在年齡、病程、病情、中醫(yī)證候、局部體征等方面差異無統(tǒng)計學意義(P0.05)。6.治療組的療效結果與不同年齡、不同病程及不同的病情程度患者相關性無明顯統(tǒng)計學差異(P0.05)。7.安全性檢測:兩組患者治療前后分別測定血常規(guī)、尿常規(guī)、糞常規(guī)、肝功能、腎功能、常規(guī)心電圖均無明顯異常,這表明清熱消痛湯聯合康婦消炎栓用藥安全可靠,尚無毒副作用。結論:清熱消痛湯聯合康婦消炎栓能改善濕熱瘀結型盆腔炎性疾病后遺癥患者的臨床癥狀及體征,減少盆腔積液和縮小附件區(qū)包塊,于停藥1個月后,仍能維持較好的治療效果,減少其復發(fā)率,并且使用安全。
[Abstract]:Objective: to observe the clinical effect of Qingre Xiaotong decoction combined with Kangfuxiaoyan suppository in treating the sequelae of damp-heat stasis type pelvic inflammatory disease, and to evaluate objectively the effectiveness of the prescription in improving the clinical symptoms and signs of the patients. Improve the cure rate and reduce the possibility of recurrence. Methods: 60 patients were randomly divided into two groups: group A (treatment group: Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository group) (control group: gynecological Qianjin group: control group: gynecological Qianjin group). Combined with Kangfu Xiaoyan suppository group, 30 cases in each group. The clinical changes of patients before and after one course of treatment, 2 courses of treatment, 3 courses of treatment and 1 month after withdrawal were observed, and the clinical efficacy was evaluated by statistical analysis. The result is 1: 1. Comprehensive curative effect comparison: after one course of treatment, the total effective rate of the treatment group was 80%, the total effective rate of the control group was 73.33, and there was no significant difference between the two groups (P 0.05), which indicated that both groups could improve the clinical symptoms of the patients, and the curative effect was the same; after two courses of treatment, The total effective rate of the treatment group was 90.00%, the total effective rate of the control group was 76.67. The difference between the two groups was P 0.05, which indicated that the comprehensive curative effect of the treatment group was better than that of the control group. The total effective rate of the treatment group was 93.33 and the total effective rate of the control group was 80.00.The difference between the two groups shows that the comprehensive curative effect of the treatment group is still superior to that of the control group. It shows that the comprehensive curative effect of the treatment group is still higher than that of the control group. Comparison of TCM syndromes: after three courses of treatment, the total effective rate of TCM syndromes in the treatment group was 96.6767 and that in the control group was 83.33.The difference between the two groups was statistically significant, indicating that the improvement of the curative effect of TCM syndrome in the treatment group was better than that in the control group. Comparison of local physical signs: after 3 courses of treatment, the scores of local signs of the two groups were compared, the difference was statistically significant (P 0.05), indicating that the improvement of physical signs in the treatment group was better than that in the control group. 4. Ultrasound comparison: after three courses of treatment, the results of pelvic ultrasound examination were compared (pelvic effusion and adnexal mass were not significantly different (P 0.05), indicating that both groups could reduce pelvic effusion and reduce adnexal mass, and the curative effect was equal to. 5. Feasibility analysis: there was no significant difference between the two groups in age, course of disease, condition, TCM syndromes, local signs and so on before treatment. In the treatment group, there was no significant difference in the correlation between the curative effect and the patients of different ages, different course of disease and different degree of disease. Safety test: blood routine, urine routine, fecal routine, liver function, kidney function, routine electrocardiogram were not significantly abnormal before and after treatment, which indicated that Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository was safe and reliable. There are no side effects. Conclusion: Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository can improve the clinical symptoms and signs of the sequelae of damp-heat stasis type pelvic inflammatory disease, reduce pelvic effusion and reduce the adnexal block. Can still maintain good therapeutic effect, reduce its recurrence rate, and use safely.
【學位授予單位】：福建中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R271.9

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