本文選題：運(yùn)氣證治方紫菀湯　切入點(diǎn)：外感咳嗽　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討五運(yùn)六氣理論臨床運(yùn)用前景,選擇陳無擇《三因極—病證方論》中記載的運(yùn)氣證治方紫菀湯,觀察該運(yùn)氣證治方治療肺虛感寒兼郁熱型外感咳嗽的臨床療效,以揭示在五運(yùn)六氣理論指導(dǎo)下,運(yùn)用運(yùn)氣證治方(紫菀湯)的價值優(yōu)勢,充分顯示中醫(yī)"天人相應(yīng)"理論在外感咳嗽辨治中的價值,以豐富外感咳嗽中醫(yī)辨治手段,并擴(kuò)大紫菀湯的應(yīng)用范圍。方法:此研究以肺虛感寒,兼郁熱證型的外感咳嗽患者為研究對象,采用小樣本對照試驗(yàn),隨機(jī)分組,中藥治療組和西藥對照組比例為2:1,中藥組60例,西藥組30例。中藥組予紫菀湯治療,療程:4周,隨訪半年;西藥組予惠菲寧治療。療程:4周,隨訪半年。對比兩組治療前后各觀察點(diǎn)的中醫(yī)證候總積分(肺虛感寒,兼郁熱證)、肺虛癥狀積分以及LCQ評分,并觀察其起效時間和復(fù)發(fā)次數(shù)。結(jié)果:(1)總體療效:中藥組總有效率90%;西藥組總有效率73.3%;根據(jù)SPSS2.0統(tǒng)計(jì)軟件分析,中藥組的總體療效大于西藥組(P=0.0430.05)。(2)中醫(yī)證候總積分(肺虛感寒,兼郁熱證):根據(jù)參與試驗(yàn)的患者試驗(yàn)數(shù)據(jù),兩組藥物治療前后的癥狀積分均逐步降低,但中藥組相較于西藥組更加有效的降低癥狀積分,緩解臨床癥狀(P0.05)。(3)肺虛癥狀積分:參與試驗(yàn)的患者的肺虛癥狀經(jīng)中藥與西藥治療后,癥狀積分均逐步降低,治療前后對照,中藥組治療肺虛癥狀具有明顯的效果(P0.05)。(4)LCQ評分:參與試驗(yàn)的外感咳嗽患者,經(jīng)治療后,各區(qū)域總分逐步上升,兩組治療前后相比,中藥組具有更好的控制咳嗽的效果(P0.05)。(5)起效時間及復(fù)發(fā)次數(shù):兩組藥物服用后,相較于西藥組,中藥組起效時間更快(P0.01)。根據(jù)治療后半年內(nèi)的隨訪數(shù)據(jù),中藥組能更加有效增強(qiáng)體質(zhì),減少咳嗽復(fù)發(fā)次數(shù)(P0.05)。
[Abstract]:Objective: to explore the prospect of clinical application of the theory of "five Transport and six Qi", select Chen Wu-xuan "San Jinji-Disease Syndrome Formula", and observe the clinical curative effect of this kind of lucky syndrome prescription on the treatment of lung deficiency, cold and stagnation heat type exogenous cough. Under the guidance of the theory of "five Transport and six Qi" and using the value advantage of "Qi Zhi Fang" (Aster decoction), this paper fully shows the value of the theory of "Heaven and Man corresponding" in the treatment of exogenous cough, and enriches the means of TCM differentiation and treatment of exogenous cough. Methods: in this study, external cough patients with deficiency of lung and heat syndrome were selected as the research objects, and small sample control trial was used to group them randomly. The proportion of traditional Chinese medicine treatment group and western medicine control group was 2: 1, 60 cases in traditional Chinese medicine group and 30 cases in western medicine group. The traditional Chinese medicine group was treated with Aster decoction for 4 weeks and followed up for half a year; the western medicine group was treated with Huifining for 4 weeks. Follow up for half a year. Compare the total score of TCM syndromes before and after treatment between the two groups (lung deficiency feeling cold, stagnation and heat syndrome, lung deficiency symptom score and LCQ score). Results: the total effective rate of traditional Chinese medicine group was 90 and that of western medicine group was 73.3 percent. According to SPSS2.0 statistical software analysis, the total curative effect of traditional Chinese medicine group was greater than that of western medicine group. According to the experimental data of the patients participating in the experiment, the symptom scores of the two groups decreased gradually before and after treatment, but the Chinese medicine group was more effective than the western medicine group in reducing the symptom score. Symptom score of lung deficiency: after treatment with traditional Chinese medicine and western medicine, the symptom score of patients with lung deficiency decreased gradually, compared with that before and after treatment. After treatment, the total scores of the patients with external cough in the test group increased gradually, compared with the two groups before and after treatment, the Chinese medicine group had obvious effect in treating the symptoms of lung deficiency and the score of LCQ was higher than that of the control group before and after treatment, and the scores of the two groups were higher than those of the control group. The Chinese medicine group had better effect of controlling cough (P0.05. 5) the time of onset and the times of recurrence: after the two groups of drugs were taken, the onset time of the Chinese medicine group was faster than that of the western medicine group. According to the follow-up data of half a year after treatment, the Chinese medicine group had a faster onset time than the western medicine group. The traditional Chinese medicine group can strengthen the physique more effectively, reduce the cough relapse times P0.05.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R256.11

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