本文關(guān)鍵詞：補腎活血膏方治療支氣管哮喘臨床緩解期的臨床觀察及對FeNO的干預(yù)作用　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

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【摘要】：目的探討補腎活血膏方對支氣管哮喘臨床緩解期患者的ACT評分、血清IgE、肺功能(FEV1%和PEF%)、呼出氣一氧化氮(FeNO)的影響。觀察補腎活血膏方對支氣管哮喘臨床緩解期的臨床療效及對FeNO的干預(yù)情況。方法1.門診選取支氣管哮喘屬于臨床緩解期患者共60例,隨機分為30例治療組和30例對照組。分別測定兩組患者的FeNO值,同時測定患者的ACT評分、血清IgE、肺功能(FEV1%和PEF%)等指標(biāo)并記錄作為參考。2.治療組予補腎活血膏方聯(lián)合吸入信必可,一日兩次,一次一吸,時間為45天左右,后繼續(xù)信必可吸入治療,共為期6個月;對照組單純吸入信必可治療,為期6個月隨訪。療程結(jié)束后再次比對FeNO、ACT評分、血清IgE、肺功能(FEV1%和PEF%)等指標(biāo)。結(jié)果1.兩組患者在ACT的評分、FeNO的水平、血清IgE、肺功能(PEF%)等指標(biāo)的治療前后比較中,有顯著的統(tǒng)計學(xué)差異(P0.01),提示治療有顯著效果。但肺功能(FEV1%)治療后較前未見明顯改善。2.兩組間比較,治療組FeNO、肺功能(PEF%)、血清IgE下降治療后較對照組改善更明顯(P0.05)。結(jié)論補腎活血膏方治療哮喘臨床緩解期患者能降低FeNO的數(shù)值,在臨床癥狀改善、肺功能(PEF%)、血清IgE等指標(biāo)均優(yōu)于單純信必可吸入治療。一定程度上體現(xiàn)了中醫(yī)治療哮喘的優(yōu)勢,闡明其現(xiàn)代科學(xué)依據(jù)。
[Abstract]:Objective to study the ACT score, serum IgE, pulmonary function, FEV1% and PEF5 of Bushen Huoxue Ointment in patients with bronchial asthma. Exhaled nitric oxide (Feno). To observe the clinical effect of Bushen Huoxue Ointment on bronchial Asthma in remission period and its intervention on FeNO. 1. Totally 60 cases of bronchial Asthma were selected from outpatient clinic. Patients were randomly divided into treatment group and control group. The FeNO, ACT score and serum IgE were measured respectively. Pulmonary function, FEV1% and PEF) were recorded and recorded as reference .2.The treatment group was given Bushen Huoxue Ointment combined inhalation of Bushen Huoxue Ointment, twice in 1st, once a time, the time was about 45 days. To continue inhalation therapy for a total of 6 months; Patients in the control group were treated with inhaled cinnabine and followed up for 6 months. After the course of treatment, the FeNol ACT score and serum IgE were compared again. Results 1.The ACT scores, serum IgE and pulmonary function were compared between the two groups before and after treatment. 2. There was a significant statistical difference (P 0.01), indicating that the treatment had a significant effect, but the pulmonary function and FEV1 after treatment did not show significant improvement. 2. 2. Comparison between the two groups, the treatment group FeNO. Compared with the control group, the decrease of serum IgE was significantly improved by P0.05.Conclusion Bushen Huoxue Ointment can reduce the value of FeNO in patients with asthma in clinical remission period. In the improvement of clinical symptoms, pulmonary function and serum IgE were better than that of Xinji inhalable therapy, which to some extent reflected the superiority of TCM in treating asthma and clarified its modern scientific basis.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R256.12

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