本文關(guān)鍵詞：黃芪柏術(shù)湯促進(jìn)熱毒熾盛型低位肛癰術(shù)后創(chuàng)面愈合的臨床療效觀察　出處：《福建中醫(yī)藥大學(xué)》2017年碩士論文　論文類(lèi)型：學(xué)位論文

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【摘要】：目的:探討熱毒熾盛型低位肛周膿腫患者術(shù)后,口服黃芪柏術(shù)湯治療后對(duì)創(chuàng)面分泌物、創(chuàng)面疼痛、創(chuàng)面肉芽組織生長(zhǎng)情況、創(chuàng)面愈合情況、創(chuàng)面愈合時(shí)間及總療效等方面的影響。方法:在臨床上選擇符合納入標(biāo)準(zhǔn)的低位肛周膿腫術(shù)后患者60例,隨機(jī)分為兩組,按隨機(jī)數(shù)字表隨機(jī)分為對(duì)照組和治療組各30例。兩組在手術(shù)前后采用相同的常規(guī)治療基礎(chǔ)上,治療組于術(shù)后第1天予口服黃芪柏術(shù)湯,日一劑,分兩次服,連服一周;對(duì)照組予常規(guī)治療。觀察兩組患者術(shù)后第1天、第7天、第14天、第21天創(chuàng)面滲液及分泌物、創(chuàng)面疼痛程度,創(chuàng)面肉芽組織生長(zhǎng)情況等進(jìn)行評(píng)分并記錄數(shù)據(jù)。在術(shù)后第1天、術(shù)后第7天、第14天、第21天分別測(cè)量?jī)山M患者創(chuàng)面長(zhǎng)度、寬度,比較創(chuàng)面愈合時(shí)間及術(shù)后2個(gè)月總療效。結(jié)果:入選的60例患者,收集時(shí)無(wú)病例脫落。治療前將兩組病例的性別、年齡、病程分布、創(chuàng)面分泌物、創(chuàng)面疼痛程度、創(chuàng)面肉芽組織生長(zhǎng)情況等進(jìn)行比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義,治療前基線一致,具有可比性。研究結(jié)果分析如下:(1)創(chuàng)面滲液及分泌物情況:兩組術(shù)后第7、14、21天創(chuàng)面分泌物情況比較均呈顯著性差異(P0.05),治療組明顯優(yōu)于對(duì)照組。(2)創(chuàng)面肉芽組織生長(zhǎng)情況:兩組術(shù)后第7、14、21天肉芽組織生長(zhǎng)情況比較均呈顯著性差異(P0.05),治療組明顯優(yōu)于對(duì)照組。(3)創(chuàng)面長(zhǎng)度、寬度和創(chuàng)面愈合時(shí)間:兩組術(shù)后第7天,創(chuàng)面長(zhǎng)度、寬度比較無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。兩組術(shù)后第14、21天,創(chuàng)面長(zhǎng)度、寬度比較有統(tǒng)計(jì)學(xué)意義(P0.05),治療組優(yōu)于對(duì)照組。治療組平均創(chuàng)面愈合時(shí)間(26.73±2.448)天,對(duì)照組平均創(chuàng)面愈合時(shí)間(32.23±4.312)天,創(chuàng)面愈合時(shí)間比較存在顯著性差異(P0.05),治療組平均愈合時(shí)間明顯短于對(duì)照組。(4)創(chuàng)面疼痛情況:兩組術(shù)后第7、14、21天創(chuàng)面疼痛情況比較均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。(5)總體療效比較:術(shù)后2個(gè)月觀察兩組總療效,創(chuàng)面愈合率100%,創(chuàng)面上皮完全覆蓋,疤痕堅(jiān)實(shí)。治療組有效率93.33%,對(duì)照組有效率83.33%,兩組對(duì)比統(tǒng)計(jì)學(xué)無(wú)顯著性差異(P0.05)。結(jié)論:黃芪柏術(shù)湯能夠有效地減輕術(shù)后并發(fā)癥,可明顯減少創(chuàng)面滲液及分泌物、促進(jìn)創(chuàng)面肉芽組織生長(zhǎng),加快創(chuàng)面愈合,縮短愈合周期等,從而提高患者生活質(zhì)量。且用藥過(guò)程中未出現(xiàn)不良反應(yīng),臨床值得推廣應(yīng)用。
[Abstract]:Objective: to investigate the effect of Huangqi Peshuzhu decoction on wound secretion, wound pain, granulation tissue growth and wound healing after operation in patients with low perianal abscess with incandescent heat toxin. Methods: 60 patients with low perianal abscess were randomly divided into two groups. On the basis of the same routine treatment before and after operation, the treatment group was given orally Astragalus Boxuzhu decoction on the first day after operation, once a day, divided into two groups. For a week; The patients in the control group were treated with routine therapy. The wound exudates and secretions were observed on the 1st, 7th, 14th and 21st day after operation, and the degree of wound pain was observed. The wound granulation tissue growth was scored and the data were recorded. The wound length and width were measured on the first day, the 7th day, the 14th day and the 21st day after operation. Results: there were 60 patients who were selected, no cases fell off at the time of collection. Before treatment, the sex, age, course of disease, wound secretion of the two groups were compared. The degree of wound pain, granulation tissue growth and so on were compared, the differences were not statistically significant, the baseline before treatment was the same. The results of the study were as follows: 1) wound exudation and secretion: there was significant difference between the two groups on the 1st day after operation (P 0.05). The granulation tissue growth in the treatment group was significantly better than that in the control group (P 0.05): the granulation tissue growth of the treatment group was significantly higher than that of the control group (P 0.05). The length, width and healing time of wound in the treatment group were significantly better than those in the control group (P < 0.05): the length and width of the wound were not significantly different between the two groups on the 7th day after operation (P 0.05). After 21 days, the length and width of wound were significantly higher in the treatment group than in the control group, and the average wound healing time in the treatment group was 26.73 鹵2.448 days. In the control group, the average wound healing time was 32.23 鹵4.312 days, and there was significant difference in wound healing time (P 0.05). The average healing time in the treatment group was significantly shorter than that in the control group. There was no significant difference in the total curative effect between the two groups 2 months after operation, the wound healing rate was 100 and the wound epithelium was completely covered. The effective rate of the treatment group was 93.33 and that of the control group was 83.33%. There was no significant difference between the two groups (P 0.05). Conclusion: Huangqi Baizhu decoction can effectively reduce postoperative complications, can significantly reduce wound effusion and secretion, promote the growth of wound granulation tissue. In order to improve the quality of life of the patients, the wound healing was accelerated and the healing cycle was shortened. There were no adverse reactions in the course of medication, so it is worth popularizing and applying clinically.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R266

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