DEAD-box家族蛋白在癌癥中的研究進(jìn)展
發(fā)布時間:2019-03-31 15:31
【摘要】:DEAD-box家族蛋白是一類ATP依賴的RNA解旋酶,在RNA代謝的過程中發(fā)揮重要的作用。DEAD-box家族蛋白可通過調(diào)節(jié)癌基因和抑癌基因的表達(dá)及腫瘤相關(guān)信號通路等影響細(xì)胞的增殖、分化、凋亡,進(jìn)而發(fā)揮促癌或抑癌的作用。
[Abstract]:DEAD-box family proteins are ATP-dependent RNA helicases that play an important role in the metabolism of RNA. Dead-box family proteins affect cell proliferation by regulating the expression of oncogenes and tumor suppressor genes and tumor-related signaling pathways. Differentiation, apoptosis, and then play a role in promoting or suppressing cancer.
【作者單位】: 中南大學(xué)湘雅醫(yī)學(xué)院附屬?卺t(yī)院中心實驗室;
【基金】:國家自然科學(xué)基金(81460450,81760465) 海南省自然科學(xué)基金創(chuàng)新研究團(tuán)隊項目(2017CXTD010);海南省自然科學(xué)基金(20168317)~~
【分類號】:R730
,
本文編號:2451041
[Abstract]:DEAD-box family proteins are ATP-dependent RNA helicases that play an important role in the metabolism of RNA. Dead-box family proteins affect cell proliferation by regulating the expression of oncogenes and tumor suppressor genes and tumor-related signaling pathways. Differentiation, apoptosis, and then play a role in promoting or suppressing cancer.
【作者單位】: 中南大學(xué)湘雅醫(yī)學(xué)院附屬?卺t(yī)院中心實驗室;
【基金】:國家自然科學(xué)基金(81460450,81760465) 海南省自然科學(xué)基金創(chuàng)新研究團(tuán)隊項目(2017CXTD010);海南省自然科學(xué)基金(20168317)~~
【分類號】:R730
,
本文編號:2451041
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