【摘要】：目的探討臨床藥師參與糖皮質激素引起醫(yī)源性庫欣綜合征藥物治療的作用。方法臨床藥師對1例口服地塞米松片長達10年,繼發(fā)醫(yī)源性庫欣綜合征、糖尿病等疾病的患者提出處置分析建議和藥學監(jiān)護。結果與結論患者逐漸減量至停用地塞米松片,改為醋酸氫化可的松20 mg,bid替代治療,減藥過程中未出現(xiàn)停藥反應及反跳現(xiàn)象,對伴發(fā)疾病進行對應治療后予以出院。臨床藥師在提高患者用藥準確性方面具有重要作用,且有助于避免患者藥源性藥物不良反應的發(fā)生及不必要的經(jīng)濟負擔。
[Abstract]:Objective to investigate the role of clinical pharmacists in the treatment of iatrogenic Cushing syndrome induced by glucocorticoid. Methods A patient with iatrogenic Cushing's syndrome and diabetes mellitus was treated with oral dexamethasone tablets for 10 years. Results and conclusion the patients gradually reduced to the discontinuation of dexamethasone tablets and were replaced with hydrocortisone acetate 20 mg,bid replacement therapy. There was no withdrawal reaction and rebound phenomenon in the course of drug reduction. The patients were discharged from the hospital after corresponding treatment for the associated diseases. Clinical pharmacists play an important role in improving the accuracy of drug use and help to avoid the occurrence of drug-induced adverse drug reactions and unnecessary economic burden.
【作者單位】： 首都醫(yī)科大學附屬北京朝陽醫(yī)院藥事部;南京大學醫(yī)學院附屬南京鼓樓醫(yī)院藥學部;
【分類號】：R977.1

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