【摘要】：過期藥品逆向物流網(wǎng)絡(luò)設(shè)計(jì)成為醫(yī)藥安全領(lǐng)域迫切需要解決的關(guān)鍵問題.本文考慮居民的選擇行為,引入回收企業(yè)對(duì)居民區(qū)以及政府對(duì)回收企業(yè)的補(bǔ)貼激勵(lì),構(gòu)建了基于雙層規(guī)劃的過期藥品逆向物流網(wǎng)絡(luò)優(yōu)化模型,并設(shè)計(jì)了求解該模型的分層遺傳算法,通過算例得到了不同方案下過期藥品逆向物流由分散到集中的網(wǎng)絡(luò)結(jié)構(gòu).此外,考慮兩種激勵(lì)策略及模型參數(shù)的影響,設(shè)計(jì)四個(gè)實(shí)驗(yàn)進(jìn)行分析討論,研究表明:同時(shí)加大對(duì)醫(yī)藥企業(yè)及居民區(qū)的補(bǔ)貼策略更有利于調(diào)動(dòng)企業(yè)及居民參與回收過期藥品的積極性;企業(yè)成本與居民區(qū)成本存在此消彼長(zhǎng)的相互作用關(guān)系;單位藥品運(yùn)輸成本對(duì)居民區(qū)成本有較大影響,而居民區(qū)擁有過期藥品的數(shù)量對(duì)企業(yè)和居民區(qū)成本均有明顯影響.
[Abstract]:The reverse logistics network design of expired drugs has become a key problem in the field of pharmaceutical safety. In this paper, considering the residents' choice behavior and introducing the subsidy incentives of recycling enterprises to residential areas and government to recycling enterprises, an optimization model of reverse logistics network of expired drugs based on bilevel programming is constructed. A hierarchical genetic algorithm is designed to solve the model. The network structure of reverse logistics of expired drugs is obtained by examples. In addition, considering the influence of two kinds of incentive strategies and model parameters, four experiments are designed to analyze and discuss. The research shows that increasing the subsidy strategy to pharmaceutical enterprises and residential areas is more helpful to arouse the enthusiasm of enterprises and residents to participate in the recovery of expired drugs; There is a mutual relationship between the cost of enterprise and the cost of residential area, the cost of unit drug transportation has great influence on the cost of residential area, and the quantity of expired drugs in residential area has obvious influence on the cost of enterprise and residential area.
【作者單位】： 上海海事大學(xué)物流研究中心;上海海事大學(xué)經(jīng)管學(xué)院;
【基金】：教育部博士點(diǎn)基金項(xiàng)目(20123121110004) 上海海事大學(xué)研究生創(chuàng)新基金項(xiàng)目(2013ycx061) 上海海事大學(xué)優(yōu)秀博士學(xué)位論文培育項(xiàng)目(2014bxlp002)
【分類號(hào)】：R95;TP18

【參考文獻(xiàn)】

相關(guān)期刊論文 前5條

1 孫會(huì)君,高自友;基于雙層規(guī)劃的供應(yīng)鏈二級(jí)分銷網(wǎng)絡(luò)優(yōu)化設(shè)計(jì)模型[J];管理工程學(xué)報(bào);2004年01期

2 汪傳旭;蔣良奎;;基于雙層規(guī)劃的區(qū)域港口內(nèi)陸運(yùn)輸網(wǎng)絡(luò)優(yōu)化決策[J];管理工程學(xué)報(bào);2008年04期

3 劉枚蓮;李慧蘭;邱建偉;;基于模糊規(guī)劃的電子廢棄物逆向物流網(wǎng)絡(luò)設(shè)計(jì)[J];工業(yè)工程與管理;2011年02期

4 黃玉蘭;劉誠(chéng);付小勇;;醫(yī)藥逆向物流網(wǎng)絡(luò)優(yōu)化的設(shè)計(jì)[J];統(tǒng)計(jì)與決策;2008年19期

5 李硯;杜綱;劉波;;基于混合遺傳算法的魯棒雙層規(guī)劃求解[J];統(tǒng)計(jì)與決策;2012年19期

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 張麗萍;張蒙;白羽;;基于交叉規(guī)劃的訂貨策略優(yōu)化模型及求解算法[J];北京建筑工程學(xué)院學(xué)報(bào);2012年02期

2 桂賢;杜綱;;不確定條件下供應(yīng)鏈二級(jí)分銷網(wǎng)絡(luò)的優(yōu)化研究[J];北京理工大學(xué)學(xué)報(bào)(社會(huì)科學(xué)版);2007年01期

3 韋增欣;陳進(jìn)來;陳巧萍;羅朝暉;;雙模式的擁擠收費(fèi)雙層規(guī)劃模型[J];重慶理工大學(xué)學(xué)報(bào)(自然科學(xué)版);2010年07期

4 徐海珠;朱建沖;謝友武;汲萬峰;;基于雙層規(guī)劃的裝備調(diào)配系統(tǒng)建模研究[J];重慶交通大學(xué)學(xué)報(bào)(自然科學(xué)版);2009年06期

5 劉環(huán)宇;宋瑞;許旺土;韓璧t，

本文編號(hào)：2345297