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紅細胞儲存損傷研究進展

發(fā)布時間:2018-03-17 15:06

  本文選題:紅細胞 切入點:儲存損傷 出處:《中國輸血雜志》2017年09期  論文類型:期刊論文


【摘要】:本文回顧了近年來紅細胞儲存損傷的國內外文獻,從儲存紅細胞的理化性狀、生物代謝、獻血者個體差異、血袋與保存液不同、白細胞去除等紅細胞儲存損傷的相關影響因素,介紹了紅細胞儲存損傷的最新研究進展,討論了紅細胞儲存損傷熱點問題"新""老"紅細胞有無差異,并指出目前研究存在的根本問題是沒有1個統(tǒng)一的標準來定義"新""老"紅細胞。最后提出了研究紅細胞儲存損傷的重點應該放在紅細胞的療效上,而不是單純的延長保存時間等,為紅細胞儲存與相關療效的研究提供了一定指導意義。
[Abstract]:In this paper, the domestic and foreign literatures on erythrocyte storage injury were reviewed. The related factors of red blood cell storage damage, such as physical and chemical properties, biological metabolism, individual differences of blood donors, different blood bags from preservation solution, leukocyte removal and so on, were reviewed. This paper introduces the latest research progress of erythrocyte storage injury, and discusses whether there is any difference between new and old red blood cells, which is a hot issue of erythrocyte storage injury. It is pointed out that there is no unified standard to define "new" and "old" red blood cells. Finally, the emphasis of research on erythrocyte storage damage should be put on the curative effect of red blood cells. Instead of simply prolonging the storage time, it provides guidance for the study of erythrocyte storage and related therapeutic effects.
【作者單位】: 第二軍醫(yī)大學長海醫(yī)院輸血科;解放軍昆明總醫(yī)院;
【分類號】:R977.8

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