本文選題：DNA疫苗ASP　切入點：FDA　出處：《國際藥學(xué)研究雜志》2017年04期 　論文類型：期刊論文

【摘要】：正阿斯特拉藥業(yè)公司宣布DNA疫苗ASP0892獲FDA快通道審批資格,用于緩解嚴重的花生過敏反應(yīng)。該藥是應(yīng)用LAMP-Vax平臺生成的新DNA疫苗。Ⅰ期臨床試驗評價其對花生過敏的免疫反應(yīng)、耐受性和安全性�；ㄉ^敏是威脅生命的致命性過敏,微量暴露即可引起過敏反應(yīng)。目前尚無批準的有效預(yù)防藥物,只有攜帶腎上腺素自動注射器應(yīng)對意外發(fā)生的病例。LAMP-Vax平臺是突破性技術(shù),用于多種疾病疫苗研發(fā)。它包括編碼溶酶體有關(guān)的膜蛋白的短DNA序列,利用人體的自然生物化學(xué),產(chǎn)生更完全的免疫反應(yīng),包
[Abstract]:DNA vaccine ASP0892 has been approved by FDA Fast Channel for severe peanut allergies. The drug is a new DNA vaccine produced by the LAMP-Vax platform. Phase I clinical trials evaluated its immune response to peanut allergies. Tolerance and safety. Peanut allergies are life-threatening fatal allergies, which can be caused by exposure to small amounts. There is no approved effective prophylactic drug. Only automated epinephrine syringes for accidental cases. The LAMP-Vax platform is a breakthrough technology for developing vaccines for multiple diseases. It includes short DNA sequences that encode lysosomal membrane proteins, using the body's natural biochemistry. Produce a more complete immune response, package
【分類號】：R97
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本文編號：1603317