本文關(guān)鍵詞： 心肌梗死 血小板聚集 血小板—中性粒細胞聚集體　出處：《中國循環(huán)雜志》2017年02期 　論文類型：期刊論文

【摘要】：目的:本文探討血小板—中性粒細胞聚集體(PNA)在急性ST段抬高型心肌梗死(STEMI)患者中的表達。方法:共計納入于我院心內(nèi)科住院的STEMI患者40例為STEMI組,同期收集健康查體者30例為對照組。于入院即刻抽取靜脈血,應(yīng)用流式細胞儀分別檢測PNA、血小板—單核細胞聚集體(PMA)和血小板—淋巴細胞聚集體(PlyA)表達水平。比較兩組PNA、PMA和PlyA表達水平的差異。結(jié)果:與對照組相比,STEMI組PlyA(P=0.245)和PMA(P=0.312)水平升高,但差異無統(tǒng)計學(xué)意義。STEMI組PNA水平明顯高于對照組(P0.05),差異具有統(tǒng)計學(xué)意義。相關(guān)性分析表明,血小板-白細胞聚集體(PLA)水平與肌酸激酶同工酶(r=0.4992,P0.01)和肌鈣蛋白Ⅰ(r=0.4365,P0.01)呈正相關(guān)。結(jié)論:本研究表明,在STEMI患者中PLA尤其是PNA水平明顯增高,提示高水平的PNA可以作為急性心肌梗死的一個新指標。
[Abstract]:Objective: to investigate the role of platelet-neutrophil aggregates (PNAs) in acute ST-segment elevation myocardial infarction (STEMI). Methods: a total of 40 patients with STEMI included in our department of cardiology were included in the STEMI group. 30 healthy controls were collected at the same time. Venous blood was collected immediately after admission and PNA was detected by flow cytometry. The expression levels of platelet-monocyte aggregates (PMA) and platelet-lymphocyte aggregates (Plya A) were compared between the two groups. Results: compared with the control group, the expression levels of PMA and PlyA were increased. But the difference was not statistically significant. The PNA level in STEMI group was significantly higher than that in control group (P0.05), the difference was statistically significant. The levels of PLA and creatine kinase isoenzyme rnr 0.4992P0.01) and cardiac troponin 鈪，

本文編號：1465922