本文關(guān)鍵詞： 右美托咪定 腹部腫瘤手術(shù) 鎮(zhèn)痛 鎮(zhèn)靜　出處：《中國老年學雜志》2017年16期 　論文類型：期刊論文

【摘要】：目的評估麻醉誘導前應(yīng)用右美托咪定對老年腹部腫瘤手術(shù)患者術(shù)后鎮(zhèn)痛和鎮(zhèn)靜效果的影響。方法以行腹部腫瘤手術(shù)老年患者120例為研究對象,隨機分為觀察組(60例)和對照組(60例)。觀察組患者在麻醉誘導前給予靜脈泵注右美托咪定,對照組患者麻醉誘導前靜脈泵注生理鹽水。比較兩組患者術(shù)后3、6、12、24、48 h各時間點的視覺模擬評分(VAS)、Ramsay鎮(zhèn)靜評分,比較兩組患者術(shù)后48 h自控鎮(zhèn)痛泵的使用次數(shù)和不良反應(yīng)情況。結(jié)果觀察組術(shù)后6、12、24、48 h的VAS評分分別為(4.33±0.91)、(3.06±0.66)、(2.39±0.61)和(2.30±0.60),均明顯低于對照組(P0.05)。觀察組術(shù)后12、24、48 h的Ramsay評分分別為(0.90±0.36)、(0.91±0.39)和(0.86±0.36),均明顯低于對照組(P0.05)。觀察組術(shù)后48 h的自控鎮(zhèn)痛泵的使用次數(shù)為(1.91±0.81),對照為(5.81±1.33),兩組間差異顯著(P0.05)。觀察組的不良反應(yīng)發(fā)生率明顯低于對照組(10.0%vs.26.7%)(P0.05)。結(jié)論麻醉誘導前應(yīng)用右美托咪定能明顯改善老年腹部腫瘤手術(shù)患者的術(shù)后疼痛,起到較好的鎮(zhèn)靜作用,且不良反應(yīng)少。
[Abstract]:Objective to evaluate the effect of dexmetomidine before anesthesia induction on postoperative analgesia and sedation in elderly patients with abdominal tumor. Patients in the observation group were given intravenous injection of dexmetomidine before anesthesia induction, and 60 patients in the control group were treated with dexmetidine before anesthesia induction. Patients in the control group were treated with intravenous infusion of normal saline before anesthesia induction. Visual analogue scores and Ramsay sedation scores were compared between the two groups at each time point of 48 hours after operation. Results the VAS scores of the two groups were 4.33 鹵0.91 鹵0.66 鹵0.61 and 2.39 鹵0.61 respectively, which were significantly lower than those of the control group (P0.055.The Ramsay scores of the observation group at 12 ~ 2448 h) were significantly lower than those of the control group (P < 0.05). Both 0.90 鹵0.36 + 0.91 鹵0.39) and 0.86 鹵0.36 were significantly lower than those of the control group (P 0.05). The frequency of use of the self-controlled analgesic pump in the observation group at 48 hours after operation was 1.91 鹵0.81 鹵1.33, and the difference between the two groups was significant (P0.055.The incidence of adverse reactions in the observation group was significantly lower than that in the control group (10.0vs.26.7). Conclusion the incidence of adverse reactions in the observation group was significantly lower than that in the control group (10.0vs.26.7) before induction of anesthesia. Dexmetomidine can significantly improve postoperative pain in elderly patients with abdominal neoplasms. It has a good sedative effect and less adverse reactions.
【作者單位】： 自貢市第四人民醫(yī)院麻醉科;
【分類號】：R614;R730.5

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