發(fā)布時間：2018-05-21 17:42

  本文選題：快速序貫器官衰竭評估評分 + qSOFA　； 參考：《西部醫(yī)學》2016年12期

【摘要】：目的評估簡單快速易獲得的快速序貫器官衰竭評估(quick Sequential Organ Failure Assessment,qSOFA)評分能否有效篩檢顱內感染性疾病所致的膿毒癥。方法采用回顧性橫斷面研究方法,收集2016年1月1日~2016年5月31日期間在四川大學華西醫(yī)院急診科就診的顱內感染性疾病病例,按照最新的膿毒癥診斷標準Sepsis3.0,將其分為膿毒癥組及非膿毒癥組。比較兩組間一般資料與qSOFA評分有無差異,以ROC曲線評估qSOFA篩查顱內感染性疾病所致膿毒癥患者的效力。結果納入顱內感染性疾病患者186例,其中膿毒癥組108例(58.1%),非膿毒癥組78例(41.9%),膿毒癥組的qSOFA值明顯高于非膿毒癥組(P0.01)。當以qSOFA值2為截斷值時,對顱內感染性疾病致膿毒癥初篩的敏感度僅為39.8%,特異度為98.7%,陽性預測值(PPV)為97.7%,陰性預測值(NPV)為54.2%;以q SOFA值1為截斷值,qSOFA對顱內感染性疾病所致膿毒癥初篩的敏感度為88.0%,特異度為75.6%,PPV為83.3%,NPV為82.0%。結論顱內感染所致膿毒癥的發(fā)病率為58.1%,膿毒癥組的qSOFA值明顯高于非膿毒癥組,可以考慮使用qSOFA值作為早期篩查顱內感染所致膿毒癥的工具;qSOFA≥1篩檢顱內感染性疾病所致膿毒癥的效力比qSOFA≥2高,是否將qSOFA≥2作為篩檢顱內感染性疾病所致膿毒癥還需要進一步研究。
[Abstract]:Objective to evaluate the effectiveness of rapid Sequential Organ Failure assessment QSOFAA score in the screening of sepsis caused by intracranial infectious diseases. Methods A retrospective cross-sectional study was conducted to collect cases of intracranial infectious diseases from January 1, 2016 to May 31, 2016 in the Department of Emergency, Huaxi Hospital, Sichuan University. Sepsis 3.0, the latest diagnostic criteria for sepsis, was divided into sepsis group and non sepsis group. To compare the difference of general data and qSOFA score between the two groups, the effectiveness of qSOFA in the screening of patients with sepsis caused by intracranial infectious diseases was evaluated by ROC curve. Results 186 patients with intracranial infectious diseases were included, including 108 patients with sepsis (n = 108) and 78 patients with non-sepsis (n = 78). The qSOFA value of sepsis group was significantly higher than that of non-sepsis group (P 0.01). When the qSOFA value 2 is truncated, The sensitivity, specificity, positive predictive value and negative predictive value of primary screening for sepsis caused by intracranial infectious diseases were only 39.8, 98.7, 97.7 and 54.2 respectively. The specificity was 75.6 and the PPV was 83.3 and the NPV was 82.0. Conclusion the incidence of sepsis caused by intracranial infection is 58.1. The qSOFA value of sepsis group is significantly higher than that of non-sepsis group. We may consider using qSOFA value as an early tool for screening sepsis caused by intracranial infection. QSOFA 鈮，

本文編號：1920153