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靜態(tài)行為與心腦血管病死亡關(guān)系巢式病例對照研究

發(fā)布時間:2018-05-14 23:33

  本文選題:靜態(tài)行為 + 心腦血管病。 參考:《中國公共衛(wèi)生》2016年11期


【摘要】:目的了解靜態(tài)行為與心腦血管病死亡的關(guān)系。方法于2010年10月—2014年12月應(yīng)用巢式病例對照研究方法對江蘇省8 275名≥18周歲未患心腦血管病的常住居民作為研究隊列進(jìn)行隨訪,以隊列中96例新發(fā)心腦血管病死亡患者作為病例組,并按照成組設(shè)計、病例與對照1:5的原則從隨訪隊列中未發(fā)生心腦血管病事件人群中抽取480人作為對照組,應(yīng)用多因素logistic回歸分析方法,在調(diào)整可能的混雜因素后分析靜態(tài)行為與心腦血管病死亡間的關(guān)系。結(jié)果在調(diào)整年齡、文化程度、家庭平均年收入、吸煙、飲酒和血壓等因素后,每日靜態(tài)行為時間≥6 h者心腦血管病死亡風(fēng)險為每日靜態(tài)行為時間2 h者的5.94倍(95%CI=2.01~17.60);靜態(tài)行為與吸煙行為在心腦血管病死亡上存在交互作用(OR_(交互)=1.37,95%CI=1.01~3.56),現(xiàn)在吸煙同時每日靜態(tài)行為時間≥6 h者心腦血管病死亡風(fēng)險為從不吸煙且每日靜態(tài)行為時間2 h者的2.46倍(95%CI=1.03~5.88),未發(fā)現(xiàn)靜態(tài)行為與飲酒行為在心腦血管病死亡上存在交互作用(OR_(交互)=0.91,95%CI=0.78~1.06)。結(jié)論每日靜態(tài)行為時間過長可以單獨或通過與吸煙行為相互作用而增加心腦血管病的死亡風(fēng)險。
[Abstract]:Objective to investigate the relationship between static behavior and death of cardiovascular and cerebrovascular diseases. Methods A nested case-control study was conducted between October 2010 and December 2014 to follow up 8 275 residents aged more than 18 years without cardiovascular and cerebrovascular diseases in Jiangsu Province. Ninety-six newly diagnosed patients with cardiovascular and cerebrovascular diseases died in the cohort as the case group. According to the design of the group, 480 patients were selected as the control group from the population without cardiovascular and cerebrovascular diseases in the follow-up cohort according to the 1:5 principle of case and control. Multivariate logistic regression analysis was used to analyze the relationship between static behavior and death of cardiovascular and cerebrovascular diseases after adjusting for possible confounding factors. Results after adjusting for age, education, average household income, smoking, alcohol consumption and blood pressure, The risk of death of cardiovascular and cerebrovascular diseases in patients with static behavior time 鈮,

本文編號:1889984

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