【摘要】：目的探討骶尾部皮膚纖毛囊腫(cutaneous ciliated cyst,CCC)的臨床病理學(xué)特征、診斷、鑒別診斷及預(yù)后。方法回顧性分析1例骶尾部CCC的臨床病理學(xué)、組織學(xué)發(fā)生及免疫表型特征并復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果患者女童,11歲,發(fā)現(xiàn)骶尾部臀裂處贅生物、盆腔MRI尾骨后軟組織內(nèi)邊界清楚的囊腫。鏡下見真皮層及皮下組織內(nèi)囊腫形成,與表皮不相連,囊腔內(nèi)上皮細(xì)胞呈乳頭狀生長,可見鱗狀上皮化生,襯覆上皮類似輸卵管上皮,由假復(fù)層纖毛柱狀上皮及分泌細(xì)胞組成,未見胞質(zhì)內(nèi)分泌物及頂質(zhì)分泌,未見肌上皮細(xì)胞。免疫表型:上皮細(xì)胞表達(dá)ER、PAX-8,不表達(dá)GCDFP-15、TTF-1。結(jié)論骶尾部CCC屬罕見的良性囊腫,該例起源于異位的Müllerian上皮,確診主要依靠病理學(xué)形態(tài)及免疫表型,手術(shù)切除后不復(fù)發(fā)。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis, differential diagnosis and prognosis of sacrococcygeal skin ciliated cysts (cutaneous ciliated cyst,CCC). Methods A case of sacrococcygeal CCC was retrospectively analyzed in terms of clinicopathology, histopathology and immunophenotypic features. Results the 11-year-old girl found a neoplasm at the sacrococcygeal fissure and a cyst with clear internal boundaries in the soft tissue behind the pelvic MRI. Under microscope, the cysts in the dermis and subcutaneous tissue formed, which were not connected with the epidermis. The epithelial cells in the capsule were papillary. The squamous metaplasia was seen, and the lining epithelium was similar to the tubal epithelium, which was composed of the pseudostratified ciliated columnar epithelium and secretory cells. There was no cytoplasmic secretion and acroplasm secretion, and no myoepithelial cells. Immunophenotype: epithelial cells express ER,PAX-8, and do not express GCDFP-15,TTF-1. Conclusion sacrococcygeal CCC is a rare benign cyst, which originated from the ectopic M 眉 llerian epithelium. The diagnosis of sacrococcygeal CCC mainly depends on pathological morphology and immunophenotype, and does not recur after resection.
【作者單位】： 南京中醫(yī)藥大學(xué)附屬醫(yī)院病理科;南京中醫(yī)藥大學(xué)附屬醫(yī)院放射科;
【分類號】：R751

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