系統(tǒng)評價經(jīng)尿道銩激光前列腺剜除術(shù)的安全性與有效性
發(fā)布時間:2018-04-06 02:30
本文選題:銩激光前列腺剜除術(shù) 切入點:經(jīng)尿道前列腺電切術(shù) 出處:《激光雜志》2013年03期
【摘要】:目的:比較經(jīng)尿道銩激光前列腺剜除術(shù)(TmLEP)與經(jīng)尿道前列腺電切術(shù)(TURP)治療良性前列腺增生癥的安全性及有效性。方法:計算機(jī)檢索CochraneLibrary、PubMed、EMbase、維普、萬方及CNKI等在線數(shù)據(jù)庫,收集比較TmLEP和TURP治療良性前列腺增生癥的隨機(jī)對照試驗(RCT)及病例對照試驗(CCT)。經(jīng)篩選、資料提取和質(zhì)量評價后,采用RevMan 5.1軟件進(jìn)行Meta分析。結(jié)果:共納入5個研究,554例患者。Meta分析結(jié)果顯示:①在安全性方面:與TURP相比,TmLEP術(shù)中出血量較少〔WMD-7.07,CI(-8.99,-5.16)P0.00001〕、血清鈉鹽降低量少〔WMD-3.07,95%CI(-4.36,-1.78)P0.00001〕、輸血人數(shù)比例低〔RR 0.10,CI(0.02,0.42)P=0.002〕、術(shù)后留置導(dǎo)尿時間較短〔WMD-0.92,95%CI(-1.11,-0.73)P0.00001〕、住院天數(shù)較短〔WMD-1.82,95%CI(-3.36,-0.28)P=0.02〕,手術(shù)時間及術(shù)后并發(fā)癥差異無統(tǒng)計學(xué)意義(P0.05);②在有效性性方面:術(shù)后1月TmLEP的最大尿流率(Qmax)評分高于TURP〔WMD-1.37,95%CI(-2.20,-0.53)P=0.01〕,術(shù)后6、12月殘余尿量(PVR)的改善TmLEP優(yōu)于TURP。其它組間指標(biāo)差異均無統(tǒng)計學(xué)意義(P0.05)。結(jié)論:TmLEP與TURP對BPH有相似的療效。TmLEP術(shù)中出血量較少、血清鈉鹽降低量少、輸血人數(shù)少、術(shù)后留置導(dǎo)尿時間較短、住院天數(shù)較短。
[Abstract]:Objective: to compare the safety and efficacy of TmLEP and TURP in the treatment of benign prostatic hyperplasia.Methods: the online databases of Cochrane Library PubMedbase, Wiper, Wanfang and CNKI were searched, and the randomized controlled trials of TmLEP and TURP in the treatment of benign prostatic hyperplasia were compared with those in the case control trial.After screening, data extraction and quality evaluation, Meta analysis was carried out with RevMan 5.1 software.鏈悗鐣欑疆瀵煎翱鏃墮棿杈冪煭銆擶MD-0.92,95%CI(-1.11,-0.73)P0.00001銆,
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