本文選題：意識指數(shù)監(jiān)測 + 丙泊酚��； 參考：《臨床麻醉學雜志》2015年07期

【摘要】：目的觀察意識指數(shù)(index of consciousness,IoC)監(jiān)測在無痛腸鏡檢查術中的臨床效果。方法選擇自愿行無痛腸鏡的男性患者200例,年齡18~65歲,隨機均分為觀察組(IoC組)和對照組(C組)。兩組患者均采用TCI丙泊酚復合瑞芬太尼麻醉,丙泊酚血漿靶濃度從4.0μg/ml起始,瑞芬太尼0.05μg·kg-1·min-1持續(xù)泵注。IoC組IoC指數(shù)保持在50±3,根據(jù)IoC值調整丙泊酚靶濃度;C組術中根據(jù)血流動力學及體動反應調整麻醉深度。記錄給藥前即刻(T1)、睫毛反射消失(T2)、過脾曲(T3)、過肝曲(T4)和蘇醒時(T5)的MAP、HR、SpO2及鏡檢時間、丙泊酚用量、術后蘇醒時間、定向力恢復時間及正常行走時間,觀察術中不良反應發(fā)生情況。結果與C組比較,IoC組丙泊酚用量明顯減少,蘇醒時間及定向力恢復時間明顯縮短(P0.05),體動發(fā)生率明顯降低(P0.05)。兩組鏡檢時間、正常行走時間和呼吸抑制、頭暈、惡心嘔吐等不良反應發(fā)生率差異無統(tǒng)計學意義。結論 IoC監(jiān)測用于無痛腸鏡檢查術可減少麻醉藥物用量,縮短恢復時間。
[Abstract]:Objective to observe the clinical effect of (index of consciousness index IOC monitoring in painless enteroscopy. Methods 200 male patients, aged 18 to 65 years, who voluntarily underwent painless enteroscopy, were randomly divided into observation group (IOC group) and control group (C group). Both groups were anesthetized with propofol and remifentanil. The plasma target concentration of propofol began at 4.0 渭 g/ml. The IOC index of remifentanil 0.05 渭 g kg-1 min-1 continuous pump group was maintained at 50 鹵3. The anesthesia depth was adjusted according to the target concentration of propofol according to IOC value. The time of MAPHR-SPO _ 2, propofol dosage, recovery time, recovery time and normal walking time were recorded immediately before administration (T _ 1), disappearance of eyelash reflex (T _ 2), hypersplenic curvature (T _ 3), liver curvature (T _ 4) and recovery time (T _ 5). Results compared with group C, the dosage of propofol in IOC group was significantly reduced, the recovery time of recovery time and directional force were significantly shortened (P0.05), and the incidence of body movement was significantly decreased (P0.05). There was no significant difference in the incidence of adverse reactions such as microscopic examination time, normal walking time, respiratory depression, dizziness, nausea and vomiting between the two groups. Conclusion IOC monitoring for painless enteroscopy can reduce the dosage of anesthetic and shorten the recovery time.
【作者單位】： 南京中醫(yī)藥大學第二附屬醫(yī)院麻醉科;
【分類號】：R614

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