溫室作業(yè)人群長期農(nóng)藥暴露相關生物學標志物研究
[Abstract]:Objective to investigate pesticide exposure of vegetable farmers in greenhouse and to screen the early biomarkers of pesticide exposure. Methods A total of 568 greenhouse vegetable growers in Anqiu city were investigated by stratified cluster sampling in 2013. According to the cumulative exposure intensity of pesticides, they were divided into three groups: low, middle and high exposure groups. 156 farmers who were not involved in greenhouse planting and were not exposed to pesticides were selected as control group. Serum cholinesterase (Ch E) activity, serum superoxide dismutase (SOD) activity and malondialdehyde (MDA) content were measured. The results showed that compared with the control group, the whole blood Ch E activity decreased by 27.80% and 46.23%, the serum SOD activity decreased by 19.22% and 36.63%, respectively, and the content of serum SOD increased by 152.92% and 191.23%, respectively. The difference was statistically significant (P0.05). The whole blood Ch E activity, serum SOD activity and pesticide exposure intensity were negatively correlated (r = -0.667- 0.532), MDA, r = -0.504). The difference was statistically significant (P0.05). Conclusion whole blood Ch E activity, serum SOD activity and MDA content can reflect the early health effects of pesticide exposure on greenhouse growers, and can be used as biological markers of early pesticide exposure.
【作者單位】: 濰坊醫(yī)學院公共衛(wèi)生學院;
【基金】:山東省自然科學基金(ZR2013HQ015) 濰坊醫(yī)學院科技創(chuàng)新基金(K11QC1004)
【分類號】:R181.3
【參考文獻】
相關期刊論文 前3條
1 閆紹妹;翟慶峰;邢杰;李萬偉;鄭重;邱玉剛;;蔬菜大棚種植者男性生殖健康狀況及影響因素分析[J];環(huán)境衛(wèi)生學雜志;2013年04期
2 翟慶峰;李媛媛;邢杰;邱玉剛;;蔬菜大棚種植菜農(nóng)健康狀況調(diào)查[J];環(huán)境與健康雜志;2010年09期
3 李鵬;尹雅玲;詹合琴;王倩倩;朱茉莉;梁金英;趙繁榮;;長期接觸有機磷農(nóng)藥機體抗氧化能力調(diào)查[J];中國職業(yè)醫(yī)學;2010年03期
【共引文獻】
相關期刊論文 前9條
1 閆紹妹;翟慶峰;邢杰;李萬偉;鄭重;邱玉剛;;蔬菜大棚種植者男性生殖健康狀況及影響因素分析[J];環(huán)境衛(wèi)生學雜志;2013年04期
2 ;Protective Effect of Lycium barbarum L. Polysaccharide Component-Ⅱ on Endothelial Cells Injured by Paraoxon[J];Medicinal Plant;2011年01期
3 翟慶峰;李媛媛;邢杰;邵麗軍;任有勛;閆紹妹;邱玉剛;;溫室土壤有機提取物對小鼠肝腎功能的影響[J];環(huán)境與健康雜志;2012年08期
4 張敏;王秀峰;崔秀敏;王建;于世欣;;山東省蔬菜產(chǎn)區(qū)日光溫室從業(yè)者健康狀況及環(huán)境分析[J];環(huán)境與職業(yè)醫(yī)學;2014年01期
5 李鵬;尹雅玲;潘國聘;趙繁榮;王倩倩;;黃芪多糖抑制對氧磷所致血管功能障礙的作用研究(英文)[J];Plant Diseases and Pests;2011年02期
6 沈惠平;徐黎明;;溫室種植環(huán)境對作業(yè)人員神經(jīng)行為功能的影響[J];職業(yè)與健康;2012年18期
7 沈惠平;;溫室大棚種植作業(yè)環(huán)境的職業(yè)病危害因素與防護[J];職業(yè)與健康;2013年08期
8 解金洪;趙敏;;長托寧、阿托品聯(lián)合血液灌流治療重癥有機磷中毒的臨床研究[J];中國醫(yī)藥導報;2013年28期
9 張敏;王秀峰;崔秀敏;張東;劉瓊;劉媛媛;;日光溫室生產(chǎn)環(huán)境狀況與從業(yè)人員健康的關系[J];現(xiàn)代預防醫(yī)學;2014年15期
【二級參考文獻】
相關期刊論文 前10條
1 李鵬;尹雅玲;張玉林;梁金英;朱茉莉;;有機磷酸酯類化合物對機體的影響[J];安徽農(nóng)業(yè)科學;2008年31期
2 張建文,馬長利,張志新,郝子成,張志廣;蔬菜大棚微小氣候及其對菜農(nóng)健康的影響[J];環(huán)境與健康雜志;2005年05期
3 翟慶峰;李媛媛;邢杰;邱玉剛;;蔬菜大棚種植菜農(nóng)健康狀況調(diào)查[J];環(huán)境與健康雜志;2010年09期
4 李鵬;劉立英;周壽紅;吳樹金;;對氧磷對血管內(nèi)皮細胞的損傷作用及機制探討[J];中國動脈硬化雜志;2007年09期
5 韓曉峰;任江玲;胡黎明;許克新;;平?jīng)鍪兄欣夏昴行孕怨δ苷{(diào)查報告[J];中華男科學雜志;2011年08期
6 馬曉年,薛兆英,王向群,,韓會元,巖正,鄒戈;男性性功能癥狀計分測量表[J];實用男科雜志;1996年03期
7 石泉;姜寧;王國增;趙玉隆;章t
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