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吉林省扶余縣農(nóng)村居民丙型肝炎流行狀況的研究

發(fā)布時(shí)間:2018-06-18 14:33

  本文選題:丙型肝炎 + 流行; 參考:《吉林大學(xué)》2010年碩士論文


【摘要】: 本次調(diào)查研究對(duì)吉林省扶余縣更新鄉(xiāng)愿意接受調(diào)查的10個(gè)村中采取統(tǒng)一的調(diào)查表,以面訪的形式對(duì)參加對(duì)象進(jìn)行問卷調(diào)查。并于問卷當(dāng)天進(jìn)行血樣采集,檢查肝功能、丙肝抗體、乙肝表面抗原,丙肝抗體陽性者行HCVRNA的檢查。在我們下鄉(xiāng)進(jìn)行調(diào)查之前,與當(dāng)?shù)剜l(xiāng)政府、疾病控制中心取得聯(lián)系,并達(dá)成合作,由他們提前做好通知工作,做到挨家挨戶上門通知,說明我們本次調(diào)查的目的和意義,鼓勵(lì)更多的人參加本次調(diào)查。本次調(diào)查的內(nèi)容主要包括調(diào)查對(duì)象基本信息,家庭人口、吸煙史,飲酒史,既往肝炎病史、糖尿病病史、家庭成員肝病病史、輸血史、獻(xiàn)血史、安納咖注射史、周圍人安納咖注射史、修牙史、紋眉史、扎耳洞史、既往丙肝診治史等。我們發(fā)現(xiàn)有安納咖注射史的是HCV感染最強(qiáng)的相關(guān)因素(OR=11.71),其次是年齡、肝炎史、吸煙、文化程度、周圍人安納咖注射史也是HCV感染的獨(dú)立相關(guān)因素,而且我們發(fā)現(xiàn)調(diào)查地區(qū)的人群對(duì)丙肝的認(rèn)知率低,就診率低,治療率低,而感染率卻很高,存在極大的隱患,應(yīng)該引起我們?nèi)鐣?huì)的關(guān)注。結(jié)論:扶余縣更新鄉(xiāng)HCV粗感染率為49.40%,約是全國HCV感染的15.44倍,是我國丙型肝炎高發(fā)區(qū)。HCV感染與年齡、吸煙史、文化程度、肝炎史、是否有安納咖注射史、周圍人安納咖注射史有關(guān)。安納咖注射人群是扶余縣更新鄉(xiāng)農(nóng)村HCV感染的高危人群,是當(dāng)?shù)豀CV感染的主要傳播途徑扶余縣更新鄉(xiāng)丙肝感染率高、檢測(cè)率低、知曉率低、治療率低、治療效果差。扶余縣更新鄉(xiāng)面臨丙型肝炎高感染率和低發(fā)現(xiàn)率、低治療率的重大挑戰(zhàn),應(yīng)采取及時(shí)有效的策略控制發(fā)病、規(guī)范治療,減輕當(dāng)?shù)亟?jīng)濟(jì)和社會(huì)負(fù)擔(dān)。
[Abstract]:In this investigation, 10 villages in Fuyu County, Jilin Province, were surveyed with a unified questionnaire, and the participants were surveyed in the form of an interview. Blood samples were collected on the same day of the questionnaire to examine the liver function, hepatitis C antibody, hepatitis B surface antigen and hepatitis C antibody positive for HCV RNA. Before we go to the countryside for investigation, contact and cooperate with the local township government and the Centers for Disease Control and Control, so that they can do a good job of notification in advance, so that we can go door-to-door notice. This explains the purpose and significance of our investigation. Encourage more people to participate in the survey. The contents of this survey mainly include basic information of the subjects, family population, smoking history, drinking history, past history of hepatitis, history of diabetes, history of liver disease among family members, history of blood transfusion, history of blood donation, history of Anakah injection. Anakah injection history, tooth repair history, eyebrow stripe history, ear hole history, previous history of diagnosis and treatment of hepatitis C, etc. We found that the most important factor associated with HCV infection was the history of Anakah injection, followed by age, history of hepatitis, smoking, education, and the history of injection of Anakana around us, which were also independent related factors of HCV infection. Moreover, we found that the people in the investigation area have low cognition rate, low visiting rate, low treatment rate, but the infection rate is very high, there are great hidden dangers, so we should pay attention to the whole society. Conclusion: the crude infection rate of HCV in Yuexin Township of Fuyu County is 49.400.It is 15.44 times higher than that in the whole country. It is the infection rate and age, smoking history, education level, history of hepatitis and whether or not there is the history of Ana injection in the high incidence area of hepatitis C in China. The history of the injection of Anakah around people. Anaqa injection population is a high risk group of HCV infection in rural areas of Fuyu County. It is the main way of transmission of HCV infection in Fuyu County. The infection rate of hepatitis C is high, the detection rate is low, the awareness rate is low, and the therapeutic effect is poor. Yuexin Township of Fuyu County is faced with the great challenge of high infection rate, low detection rate and low treatment rate of hepatitis C. We should take timely and effective strategies to control the disease, standardize the treatment and lighten the local economic and social burden.
【學(xué)位授予單位】:吉林大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2010
【分類號(hào)】:R512.63;R181.3

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