本文選題：抑郁癥狀 + 綠茶　； 參考：《天津醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:抑郁癥已成為嚴(yán)重的世界性公共衛(wèi)生問題,研究表明飲食與其關(guān)系密切。本研究旨在通過評(píng)價(jià)天津人群非酒精性飲料(綠茶、烏龍茶、紅茶、咖啡、碳酸飲料、果蔬汁)的攝入情況和抑郁癥狀水平,探究不同非酒精性飲料與抑郁癥狀的關(guān)聯(lián)。方法:本研究利用2013-2015年“天津人群慢性低度系統(tǒng)性炎癥與健康”隊(duì)列的基線人群進(jìn)行一項(xiàng)大型的橫斷面研究。同意參加研究并滿足納入、排除標(biāo)準(zhǔn)的研究對(duì)象共有19,224人。本研究所涉及變量如下:問卷調(diào)查變量(社會(huì)人口學(xué)情況、生活習(xí)慣情況、運(yùn)動(dòng)與飲食情況、家族疾病史、個(gè)人疾病史等)、體格檢查變量(身高、體重、血壓等)和血液生化檢查變量(空腹血糖、甘油三酯、總膽固醇、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇等)。抑郁癥狀利用經(jīng)驗(yàn)證的中文版抑郁自評(píng)量表進(jìn)行評(píng)價(jià),并以40為截?cái)嘀祦?lái)指示有無(wú)抑郁癥狀;非酒精性飲料的攝入利用結(jié)構(gòu)化食物頻率問卷進(jìn)行評(píng)價(jià)。最終分析采用多元Logistic回歸分析來(lái)評(píng)價(jià)男性、女性人群中非酒精性飲料與抑郁癥狀之間的關(guān)聯(lián)。結(jié)果:本研究總?cè)巳阂钟舭Y狀存在率為35.2%,而男、女人群的存在率分別為33.3%和37.4%。經(jīng)過不同混雜因素的調(diào)整,結(jié)果顯示不同的非酒精性飲料與抑郁癥狀之間存在著不同關(guān)聯(lián)。在調(diào)整眾多混雜因素的最終模型中(調(diào)整了年齡、體質(zhì)指數(shù)、吸煙狀況、飲酒狀況、身體活動(dòng)、婚姻狀況、教育程度、職業(yè)類型、家庭總收入、親友來(lái)往情況、獨(dú)居情況、總能量攝入、代謝綜合征、EPA+DHA攝入和其他各種非酒精性飲料),有如下發(fā)現(xiàn):1.男性、女性人群中均未觀察到攝入不同類型的茶(綠茶、紅茶、烏龍茶)與抑郁癥狀之間存在有意義的關(guān)聯(lián)。2.僅在男性人群中觀察到每周攝入≥4杯咖啡與較高的抑郁癥狀存在率有關(guān),即多種混雜因素調(diào)整后發(fā)現(xiàn),與每周?1杯咖啡相比,每周2-3杯和每周≥4杯咖啡的抑郁癥狀比值比(OR)(95%置信區(qū)間,95%CI)分別為1.00(0.81,1.23)和1.25(1.02,1.53)(趨勢(shì)性P0.01)。但女性人群并未發(fā)現(xiàn)有意義的關(guān)聯(lián)。3.男性、女性中均觀察到碳酸飲料或果蔬汁與抑郁癥狀之間有意義的關(guān)聯(lián),即多因素調(diào)整后發(fā)現(xiàn),與每周?1杯相比,每周攝入≥4杯碳酸飲料的抑郁癥狀存在率在男、女人群中分別增加31%、83%,而每周攝入≥4杯果蔬汁的抑郁癥狀存在率在男、女人群中各增加65%、24%。結(jié)論:本文首次全面地探討了各種非酒精性飲料與抑郁癥狀之間的關(guān)聯(lián),并發(fā)現(xiàn)不同非酒精性飲料與抑郁癥狀存在不同關(guān)聯(lián)。今后需要更多研究探討并明確各類非酒精性飲料與抑郁癥狀的關(guān)聯(lián),明確因果關(guān)系,并闡明其中的作用機(jī)制。
[Abstract]:Objective: depression has become a serious public health problem worldwide. The purpose of this study was to explore the relationship between non-alcoholic beverages and depression symptoms by evaluating the intake and depression symptoms of non-alcoholic beverages (green tea, oolong tea, black tea, coffee, carbonated drinks, fruit and vegetable juice) in Tianjin. Methods: a large cross-sectional study was conducted in the baseline population of Tianjin population cohort of chronic low systemic inflammation and Health from 2013 to 2015. A total of 19224 subjects agreed to participate in the study and meet the inclusion, exclusion criteria. The variables involved in this study are as follows: questionnaire variables (social demography, living habits, exercise and diet, family disease history, personal disease history, etc.), physical examination variables (height, weight, etc.) Blood biochemical variables (fasting blood glucose, triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, etc. Depressive symptoms were evaluated with the Chinese version of the self-rating depression scale and 40 as the cut-off value to indicate whether there were depression symptoms. The intake of non-alcoholic drinks was evaluated by structured food frequency questionnaire. Multivariate Logistic regression analysis was used to evaluate the association between non-alcoholic beverages and depression symptoms in men and women. Results: the prevalence of depressive symptoms was 35.2g in the total population, and 33.3% in males and 37.4% in females. After adjusting for different confounding factors, the results showed that there were different correlations between different non-alcoholic beverages and depression symptoms. In the final model (adjusted for age, body mass index, smoking status, alcohol consumption, physical activity, marital status, education, type of occupation, total family income, family and friends, and living alone), Total energy intake, metabolic syndrome DHA intake and other non-alcoholic beverages, have been found as follows: 1. 1. No significant association was observed between the intake of different types of tea (green tea, black tea, and oolong tea) and depression symptoms in both men and women. It was observed that intake of more than 4 cups of coffee a week was associated with a higher prevalence of depression symptoms only in men, that is, after adjusting for multiple confounding factors, it was found that, compared with one cup of coffee per week, The depression symptom ratios of 2-3 cups per week and 鈮，

本文編號(hào)：1798673