本文關鍵詞： 出生缺陷 五歲以下 維吾爾族　出處：《新疆醫(yī)科大學》2009年碩士論文　論文類型：學位論文

【摘要】： 目的:了解伊寧縣農村的5歲以下維吾爾族兒童通過肉眼觀察即可診斷的出生缺陷的分布情況,探索可能的影響因素。方法:本研究依據全國婦幼衛(wèi)生監(jiān)測辦公室提供的《主要先天畸形診斷手冊》,北京醫(yī)科大學出版的《出生缺陷診斷圖譜》中的診斷標準對伊寧縣農村5歲以下維吾爾族兒童進行調查。調查員根據各鄉(xiāng)計劃生育專干提供的資料,對本次調查的對象進行入戶問卷調查。用1:2配比的病例對照研究方法,分析出生缺陷的危險因素。資料用條件Logistic回歸方法進行單因素和多因素分析。結果:(1)本次調查存活的出生缺陷兒童共41人,發(fā)生率為33.3/萬,男性發(fā)生率為34.8/萬,女性為31.8/萬,男女發(fā)生率之比為1.09:1。(2)出生缺陷的發(fā)生順位為唇腭裂,短肢畸形、唇裂,先天性髖關節(jié)脫位,脊柱裂、唐氏綜合癥。(3)單因素分析有統計學意義的因素為:產次、孕次、懷孕年齡、孕期疾病、父母親受教育程度、父親飲酒、家族遺傳史。多因素分析有統計學意義的為:產次、懷孕年齡、家族遺傳史。結論:本次調查雖然總的發(fā)生率低于國家監(jiān)測報道,但高于新疆婦幼監(jiān)測數據,發(fā)生順位也與報道不一致,因此應針對發(fā)生率高的出生缺陷種類,加強孕期保健的管理,廣泛開展優(yōu)生和保健知識宣傳,以進一步降低出生缺陷的發(fā)生率。
[Abstract]:Objective: to investigate the distribution of birth defects diagnosed by naked eye in Uygur children under 5 years old in the countryside of Yining County. Methods: according to the diagnosis Manual of main congenital malformations provided by the National Maternal and Child Health Surveillance Office and the Diagnostic Diagnostic Map of birth defects published by Beijing Medical University. Uygur children under 5 years of age were investigated in the rural areas of Yining County. According to the information provided by family planning professionals in various townships, A household questionnaire survey was conducted on the subjects of this survey. A case-control study with 1: 2 matching was used. The risk factors of birth defects were analyzed. The data were analyzed by conditional Logistic regression method. Results: there were 41 surviving children with birth defects, the incidence rate was 33.3 / 10 000, the incidence of male was 34.8 / 10 000, and that of female was 31.8 / 10 000. The incidence of birth defects was in the order of cleft lip and palate, short limb deformity, cleft lip, congenital dislocation of hip joint, spina bifida, Down's syndrome. Diseases during pregnancy, education level of parents, father's drinking, family genetic history. Multivariate analysis was statistically significant as follows: birth, pregnancy age, family genetic history. Conclusion: although the overall incidence of this survey is lower than the national surveillance report, But it is higher than the data of maternal and child monitoring in Xinjiang, and the sequence of occurrence is inconsistent with the report. Therefore, it is necessary to strengthen the management of health care during pregnancy and widely promote the knowledge of eugenics and health care in view of the types of birth defects with high incidence. To further reduce the incidence of birth defects.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2009
【分類號】：R174;R181.3

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