【摘要】：目的研究不同血栓直徑和血栓含量下可轉(zhuǎn)換型腔靜脈濾器用于治療肺動脈栓塞后的過濾血栓效果。方法構(gòu)建3種過濾單元形狀(L、S和W型)的可轉(zhuǎn)換型腔靜脈濾器模型,利用計算流體力學(xué)方法進(jìn)行血流動力學(xué)數(shù)值模擬,對比分析不同直徑(5、10、15 mm)和不同含量(10%、15%、20%)血栓下的過濾效果。結(jié)果血栓直徑越大,含量越多,濾器濾桿上分布的血栓體積分?jǐn)?shù)越大,濾器的過濾血栓效果越好。當(dāng)血栓直徑為5 mm時,與其他兩種濾器相比,S型濾器的過濾效果最好;當(dāng)血栓直徑為10 mm時,W型濾器的過濾效果最好;而在血栓直徑為15 mm時,S型濾器與W型濾器的過濾效果相同,均比L型濾器的過濾效果好。結(jié)論濾器的植入造成了血流動力學(xué)的改變,它的過濾效果不僅與過濾單元結(jié)構(gòu)有關(guān),還與血栓含量和血栓直徑大小有著密切相關(guān)。研究結(jié)果為新型可轉(zhuǎn)換型腔靜脈濾器的設(shè)計和臨床選擇提供了理論參考依據(jù)。
[Abstract]:Objective to study the effect of convertible vena cava filter with different thrombus diameter and thrombus content in the treatment of pulmonary embolism. Methods three kinds of filter unit shapes (L, S and W) were constructed, and the hemodynamic numerical simulation was carried out by computational fluid dynamics (CFD). The filtering effects under thrombus with different diameters (5, 10, 15 mm) and different contents (10%, 15%, 20%) were compared and analyzed. Results the larger the diameter of thrombus and the more the content of thrombus, the larger the volume fraction of thrombus distributed on the filter rod, and the better the thrombus filtering effect of the filter. When the diameter of thrombus is 5 mm, the filtering effect of S filter is the best compared with the other two filters, when the diameter of thrombus is 10 mm, the filtering effect of W filter is the best, while when the diameter of thrombus is 15 mm, the filtering effect of S filter is the same as that of W filter, which is better than that of L filter. Conclusion the implantation of filter causes hemodynamic changes, and its filtration effect is not only related to the structure of filter unit, but also closely related to thrombus content and thrombus diameter. The results provide a theoretical reference for the design and clinical selection of a new convertible vena cava filter.
【作者單位】： 內(nèi)蒙古工業(yè)大學(xué)機(jī)械學(xué)院;
【基金】：國家自然科學(xué)基金項目(51565045,81160186) 內(nèi)蒙古自治區(qū)自然科學(xué)基金項目(2015MS0803)
【分類號】：R563.5
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本文編號：2525516