【摘要】：目的探討多學(xué)科綜合呼吸康復(fù)聯(lián)合無創(chuàng)正壓通氣對(duì)老年重度慢性阻塞性肺疾病(CPOD)患者的康復(fù)效果。方法 80例老年重度COPD患者隨機(jī)分為對(duì)照組25例、康復(fù)干預(yù)Ⅰ組26例及康復(fù)干預(yù)Ⅱ組29例,對(duì)照組只采用內(nèi)科藥物治療及氧療;康復(fù)干預(yù)Ⅰ組在對(duì)照組的基礎(chǔ)上給予多學(xué)科綜合呼吸康復(fù);康復(fù)干預(yù)Ⅱ組在康復(fù)干預(yù)Ⅰ組的基礎(chǔ)上加用無創(chuàng)正壓通氣。3組患者治療前及12 w時(shí)均進(jìn)行心肺運(yùn)動(dòng)試驗(yàn)、BODE指數(shù)評(píng)分、生存質(zhì)量評(píng)分及動(dòng)脈血?dú)夥治�。結(jié)果康復(fù)干預(yù)Ⅰ組及Ⅱ組治療后的最大運(yùn)動(dòng)功率(Wmax)、最大攝氧量(VO2max)、6 min步行距離(6-MWD)、改良版英國醫(yī)學(xué)研究委員會(huì)呼吸問卷(MMRC)、BODE指數(shù)、生存質(zhì)量各項(xiàng)評(píng)分、動(dòng)脈血氧分壓(Pa O2)、動(dòng)脈血二氧化碳分壓(Pa CO2)均較康復(fù)前有顯著改善(P0.01),以上指標(biāo)和對(duì)照組治療后對(duì)比,差異有統(tǒng)計(jì)學(xué)意義(P0.05或P0.01)�？祻�(fù)干預(yù)Ⅱ組治療后的6-MWD、MMRC、生存質(zhì)量各項(xiàng)評(píng)分、Pa O2、Pa CO2較康復(fù)干預(yù)Ⅰ組有較大改善(P0.05或P0.01)。結(jié)論多學(xué)科綜合呼吸康復(fù)能顯著提高老年重度COPD患者的康復(fù)效果,在多學(xué)科呼吸康復(fù)的基礎(chǔ)上加用無創(chuàng)正壓通氣,可進(jìn)一步改善患者的呼吸困難癥狀,提高運(yùn)動(dòng)耐力及生活質(zhì)量。
[Abstract]:Objective to investigate the effect of multi-disciplinary comprehensive respiratory rehabilitation combined with non-invasive positive pressure ventilation on elderly patients with severe chronic obstructive pulmonary disease (CPOD). Methods 80 elderly patients with severe COPD were randomly divided into control group (n = 25), rehabilitation intervention group (n = 26) and rehabilitation intervention group 鈪，

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