【摘要】：目的探討重癥監(jiān)護(hù)室(ICU)呼吸機(jī)相關(guān)性肺炎(VAP)的病原菌特征與耐藥性及相關(guān)因素。方法選擇2015年3月-2017年3月期間醫(yī)院ICU收治的機(jī)械輔助性呼吸超過48h的患者380例,診斷患者是否發(fā)生VAP,統(tǒng)計(jì)分析VAP患者的病原菌分布特點(diǎn)、主要病原菌的耐藥性,采用SPSS 20.0軟件分析影響VAP發(fā)生的相關(guān)因素。結(jié)果 380例患者中,有159例患者發(fā)生VAP,占41.84%;159例感染患者中共分離出263株病原菌,以革蘭陰性菌為主,共179株占68.06%;鮑氏不動(dòng)桿菌對(duì)哌拉西林耐藥率最高;單因素分析結(jié)果顯示,年齡≥60歲、合并糖尿病、昏迷、機(jī)械通氣時(shí)間5d、住院時(shí)間14d、使用糖皮質(zhì)激素、留置胃管、抗菌藥物使用種類3種能夠顯著影響VAP的發(fā)生(P0.05)。結(jié)論 VAP病原菌以革蘭陰性菌為主,合理選擇抗菌藥物并針對(duì)相關(guān)因素加強(qiáng)管理,控制VAP發(fā)生率。
[Abstract]:Objective to investigate the pathogenic characteristics, drug resistance and related factors of (ICU) ventilator-associated pneumonia (VAP) in intensive care unit (ICU). Methods from March 2015 to March 2017, 380 patients with mechanical assisted respiration more than 48 hours from March 2015 to March 2017 were selected to diagnose the occurrence of VAP. The distribution characteristics of pathogens and drug resistance of main pathogens in VAP patients were statistically analyzed. SPSS 20.0 software was used to analyze the related factors affecting the occurrence of VAP. Results among 380 patients, 159 patients had VAPs, accounting for 41.840.A total of 263 pathogenic bacteria were isolated, mainly Gram-negative bacteria, 179 strains accounted for 68.06%, Acinetobacter baumannii had the highest resistance rate to piperacillin, and univariate analysis showed that, Age 鈮，

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