本文選題：自擬“平喘湯” + 兒童支氣管哮喘急性發(fā)作期(外寒內(nèi)熱型)�。� 參考：《廣州中醫(yī)藥大學(xué)》2012年碩士論文

【摘要】：目的： 運(yùn)用前瞻性的臨床研究方法,觀(guān)察自擬“平喘湯”治療外寒內(nèi)熱型兒童支氣管哮喘的臨床療效,同時(shí)進(jìn)行呼氣峰流速(PEF)的測(cè)定,初步探討PEF的變化與該證型癥候積分的相關(guān)性。 方法： 隨機(jī)收集符合研究標(biāo)準(zhǔn)的外寒內(nèi)熱型支氣管哮喘急性發(fā)作期的患兒共60例,其中治療組與對(duì)照組各30例。對(duì)照組采用常規(guī)治療,治療組用常規(guī)治療加用自擬“平喘湯”,治療5天后,觀(guān)察兩組治療前后中醫(yī)癥候積分和PEF的變化。運(yùn)用SPSS17.0及Excel統(tǒng)計(jì)軟件分析觀(guān)察結(jié)果。 成果： 1.綜合療效：治療組：顯效率86.67%；對(duì)照組：顯效率56.67%,(P0.05),治療組顯效率優(yōu)于對(duì)照組。 2.中醫(yī)癥候積分：治療前后經(jīng)統(tǒng)計(jì)學(xué)檢驗(yàn)兩者差異具有統(tǒng)計(jì)學(xué)意義(P0.01)。并且治療后治療組與對(duì)照組之間的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組的治療均可以減少中醫(yī)癥候積分,治療組優(yōu)于對(duì)照組。 3.治療前后PEF變化：兩組的PEF均較治療前有所提高,兩組提高的幅度經(jīng)統(tǒng)計(jì)學(xué)檢驗(yàn),兩者之間的差異有統(tǒng)計(jì)學(xué)意義(P0.05),治療組在改善PEF方面優(yōu)于對(duì)照組。 4.應(yīng)急霧化吸入次數(shù)：兩組哮喘急性發(fā)作期的治療均有應(yīng)急霧化吸入,但是治療組的霧化吸入次數(shù)少于對(duì)照組(P0.05)。 5.中醫(yī)癥候的改善與PEF的變化有一定的相關(guān)性。 結(jié)論： 1.自擬“平喘湯”聯(lián)合西醫(yī)常規(guī)治療能明顯改善外寒內(nèi)熱型兒童支氣管哮喘的中醫(yī)癥候積分,提高顯效率且在改善咳嗽、咳痰、喘息癥狀及肺部哮鳴音等主癥上優(yōu)于對(duì)照組。 2.治療前后治療組與對(duì)照組均可以提高PEF,改善氣道痙攣,緩解癥狀,但治療組優(yōu)于對(duì)照組。 3.中西醫(yī)結(jié)合治療可以減少霧化吸入次數(shù)。 4.外寒內(nèi)熱型兒童支氣管哮喘的中醫(yī)癥候變化與PEF的變化有一定的相關(guān)性。
[Abstract]:Objective: To observe the clinical effect of "Pingchuan decoction" in the treatment of bronchial asthma in children with external cold and internal heat, and to determine the peak expiratory flow rate (PEF), and to explore the correlation between the change of PEF and the symptom score of the syndrome. Methods: A total of 60 children with acute attack of external cold and internal heat asthma were randomly collected, including 30 cases in the treatment group and 30 cases in the control group. The control group was treated with routine therapy, the treatment group was treated with conventional therapy and the self-made "Pingchuan decoction" was used. After 5 days of treatment, the changes of TCM symptom score and PEF were observed before and after treatment. SPSS17.0 and Excel software were used to analyze the observation results. Outcome: 1. Comprehensive efficacy: the treatment group: the effective rate was 86.67; the control group: the effective rate was 56.67 and P0.05. The effective rate of the treatment group was better than that of the control group. 2. TCM symptom score: before and after treatment, the difference between the two was statistically significant (P 0.01). The difference between the treatment group and the control group was statistically significant (P 0.05). Both groups of treatment can reduce TCM symptom score, the treatment group is better than the control group. 3. The changes of PEF before and after treatment: the PEF of the two groups were improved compared with those before treatment, and the amplitude of the two groups was increased by statistical test. The difference between the two groups was statistically significant (P 0.05). The treatment group was superior to the control group in improving PEF. 4. The times of emergency atomization inhalation: both groups had emergency atomization inhalation during the acute attack of asthma, but the times of atomization inhalation in the treatment group were less than that in the control group (P 0.05). 5. The improvement of TCM symptoms is related to the change of PEF. Conclusion: 1. The self-made "Pingchuan decoction" combined with western medicine routine treatment can obviously improve the TCM symptom integral of children's bronchial asthma with external cold and internal heat type, and improve the effective rate and is superior to the control group in improving the main symptoms such as cough, expectoration, wheezing symptoms and lung wheezing. 2. Before and after treatment, both the treatment group and the control group could improve PEF, improve airway spasm and relieve symptoms, but the treatment group was superior to the control group. 3. Integrated Chinese and Western medicine treatment can reduce the number of atomization inhalation. 4. The changes of TCM symptoms and changes of PEF in children with external cold and internal heat type bronchial asthma are related to some extent.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類(lèi)號(hào)】：R272

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本文編號(hào)：1983623