本文選題：頂體反應(yīng)　切入點(diǎn)：受精　出處：《國(guó)外畜牧學(xué)(豬與禽)》2016年12期 　論文類(lèi)型：期刊論文

【摘要】：受精是有性生殖動(dòng)物繁育下一代必不可少的過(guò)程。在過(guò)去數(shù)十年中,我們對(duì)哺乳動(dòng)物精卵互作分子機(jī)制的理解已取得重要進(jìn)展。然而,由于禽類(lèi)的卵子較大和模擬發(fā)生在正常受精過(guò)程中的生理性多精受精過(guò)程有一定困難,我們?cè)谇蓊?lèi)精卵互作方面積累的知識(shí)并未達(dá)到類(lèi)似于在哺乳動(dòng)物上積累的水平。本文將總結(jié)目前人們對(duì)禽類(lèi)受精過(guò)程中精卵互作機(jī)制的理解,尤其著重總結(jié)精卵結(jié)合、精子的頂體反應(yīng)以及卵周膜通道形成所必需的真精子蛋白酶;解釋卵周膜中透明帶(Zona Pellucida,ZP)蛋白(ZP1和ZP3)在精卵結(jié)合、頂體反應(yīng)誘導(dǎo)以及精子蛋白酶消化作用下的精子滲透作用。我們期望:對(duì)鳥(niǎo)類(lèi)受精過(guò)程的更深刻理解,能夠?yàn)榧仪菪袠I(yè)中包括生產(chǎn)轉(zhuǎn)基因或克隆禽類(lèi)在內(nèi)的眾多應(yīng)用開(kāi)發(fā)強(qiáng)有力工具開(kāi)辟新的途徑。
[Abstract]:Fertilization is an essential process for the reproduction of the next generation of sexual reproduction animals. Over the past few decades, we have made significant progress in understanding the molecular mechanisms of sperm-egg interaction in mammals. Because of the large eggs of poultry and the difficulty of simulating the physiological polyspermatism during normal fertilization, Our knowledge of egg and egg interaction has not reached a level similar to that in mammals. In this paper, we will summarize the current understanding of the mechanism of spermatozoa interaction in poultry fertilization, with particular emphasis on sperm and egg binding. The acrosome reaction of spermatozoa and the eusperm protease necessary for the formation of perovular membrane channels; to explain the ZP1 and ZP3 proteins of Zona Pellucida ZP3 in the spermatozoa, and to explain the binding of ZP1 and ZP3 in spermatozoa. Acrosome reaction induction and sperm osmotic action by sperm protease digestion. We expect: a deeper understanding of the process of bird fertilization, It can open up new ways to develop powerful tools in poultry industry, including the production of transgenic or cloned poultry.
【分類(lèi)號(hào)】：S814
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本文編號(hào)：1636266