本文選題：肝硬化 + 肝炎�。� 參考：《中國全科醫(yī)學》2017年S1期

【摘要】：目的比較酒精性肝硬化和乙型肝炎肝硬化患者的凝血功能。方法選取2015年1月—2016年12月信陽市中心醫(yī)院收治的肝硬化患者120例,根據(jù)疾病類型分為酒精性肝硬化組(n=36)和乙型肝炎肝硬化組(n=84);另選取同期無凝血功能障礙的胃病患者118例,為對照組。比較3組患者的凝血功能指標,包括凝血酶原時間(PT)、活化部分凝血活酶時間(APTT)、國際標準化比值(INR)、凝血酶時間(TT)、纖維蛋白原(FIB)。結果 3組患者PT、APTT、INR、TT、FIB比較,差異有統(tǒng)計學意義(P0.05)。Child-Pugh分級為A、B級患者中,酒精性肝硬化組患者PT、APTT短于乙型肝炎肝硬化組患者,INR低于乙型肝炎肝硬化組患者,FIB高于乙型肝炎肝硬化組患者,差異有統(tǒng)計學意義(P0.05);兩組患者TT比較,差異無統(tǒng)計學意義(P0.05)。Child-Pugh分級為C級患者中,酒精性肝硬化組患者FIB高于乙型肝炎肝硬化組患者(P0.05);兩組患者PT、APTT、INR、TT比較,差異無統(tǒng)計學意義(P0.05)。結論酒精性肝硬化患者和乙型肝炎肝硬化患者的凝血功能存在差異,當以凝血功能評價患者的肝功能時,應考慮兩者間的差異。
[Abstract]:Objective to compare the coagulation function between alcoholic cirrhosis and hepatitis B cirrhosis. Methods 120 patients with liver cirrhosis admitted in Xinyang Central Hospital from January 2015 to December 2016 were divided into alcoholic cirrhosis group (n = 36) and hepatitis B cirrhosis group (n = 84). Control group. The indexes of coagulation function, including prothrombin time (PTT), activated partial thromboplastin time (APTTT), international standard ratio (INR), thrombin time (TT), fibrinogen (FIBN), were compared among the three groups. Results there was a significant difference among the three groups of patients with P0.05N. Child-Pugh grade of Agna B, compared with the three groups of patients with PTT APTTT / INRV FIB, and there was a significant difference among the three groups. In alcoholic cirrhosis group, PTT APTT was shorter than that in hepatitis B cirrhosis group and FIB was higher in alcoholic cirrhosis group than that in hepatitis B cirrhosis group, the difference was statistically significant (P 0.05). The FIB of alcoholic cirrhosis group was higher than that of hepatitis B cirrhosis group (P 0.05), but there was no significant difference between two groups (P 0.05). Conclusion there are differences in coagulation function between patients with alcoholic cirrhosis and patients with hepatitis B cirrhosis, and the difference between them should be considered when evaluating the liver function of patients with alcoholic cirrhosis and hepatitis B cirrhosis.
【作者單位】： 河南省信陽市中心醫(yī)院;
【分類號】：R512.62;R575.2

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