【摘要】：目的探討血清降鈣素原(PCT)、超敏C反應蛋白(hs-CRP)、白細胞計數(shù)(WBC)、中性粒細胞百分比(NEU%)在不同致病菌感染所致膿毒癥早期診斷的臨床價值,為膿毒癥患者提供風險評估。方法回顧性分析2013年10月至2015年10月在徐州市中醫(yī)院重癥醫(yī)學科(ICU)就診的血流感染致膿毒癥117例患者的臨床資料,所有患者在抗菌藥物使用之前進行血培養(yǎng),根據(jù)血培養(yǎng)結果分為革蘭陽性菌(G+菌)組和革蘭陰性菌(G-菌)組,所有患者均進行PCT、hs-CRP、WBC、NEU%檢測,分析兩組患者檢測結果的差異,評價PCT與急性生理與慢性健康狀況評分系統(tǒng)Ⅱ評分(APACHE-Ⅱ評分)和序貫器官衰竭評分(SOFA評分)的相關性。結果 117例膿毒血癥的患者中G+菌組78例,G-菌組39例;與G+菌組比較,G-菌組PCT檢測變化明顯,差異有統(tǒng)計學意義(P0.05),而hs-CRP、WBC、NEU檢測結果變化不大(P0.05);G-菌組血清PCT與SOFA評分呈正相關(r=0.536,P0.05),而與APACHE-Ⅱ評分無相關性(P0.05);G+菌組血清PCT與APACHE-Ⅱ評分、SOFA評分均無相關性(P0.05)。結論 PCT在不同致病菌感染所致膿毒癥的早期鑒別診斷和預后監(jiān)測中有一定價值,且對G-菌更靈敏。
[Abstract]:Objective to investigate the clinical value of serum procalcitonin (PCT), hypersensitive C-reactive protein (hs-CRP) and leukocyte count (WBC), neutrophil percentage (NEU%) in early diagnosis of sepsis caused by different pathogenic bacteria infection. Provides risk assessment for sepsis patients. Methods the clinical data of 117 patients with sepsis caused by blood flow infection were retrospectively analyzed from October 2013 to October 2015 in the Department of critical Medicine of Xuzhou traditional Chinese Medicine Hospital (ICU). All patients were cultured before the use of antibiotics. According to the results of blood culture, they were divided into Gram-positive bacteria (G-bacteria) group and Gram-negative bacteria (G-bacteria) groups. All patients were detected by PCT,hs-CRP,WBC,NEU%, and the difference between the two groups was analyzed. To evaluate the correlation between PCT and acute physiological and chronic health status score 鈪，

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