發(fā)布時(shí)間：2018-03-15 07:24

  本文選題：頻域光學(xué)相干斷層技術(shù)　切入點(diǎn)：青光眼　出處：《計(jì)算機(jī)輔助設(shè)計(jì)與圖形學(xué)學(xué)報(bào)》2017年06期 　論文類(lèi)型：期刊論文

【摘要】：青光眼是一種以視神經(jīng)萎縮和視野缺損為共同特征的視網(wǎng)膜疾病,是導(dǎo)致人類(lèi)失明的第二大視網(wǎng)膜疾病.青光眼的早期癥狀不明顯,因此對(duì)早期青光眼的篩選和診斷將會(huì)阻止青光眼的進(jìn)一步發(fā)展.文中提出一種評(píng)估青光眼發(fā)病機(jī)制的算法,首先利用隨機(jī)森林分割視網(wǎng)膜神經(jīng)纖維層,然后利用塊搜索算法分割視盤(pán)與視杯,最后分析兩者相關(guān)性.實(shí)驗(yàn)結(jié)果表明,視網(wǎng)膜神經(jīng)纖維層與垂直杯盤(pán)比,視杯面積以及沿盤(pán)面積比的相關(guān)性大小為0.64,0.62和0.54,驗(yàn)證了在診斷青光眼方面計(jì)算視網(wǎng)膜神經(jīng)纖維層厚度與杯盤(pán)比大小是密切相關(guān)和互補(bǔ)的,對(duì)研究青光眼的發(fā)展趨勢(shì)具有重要意義.
[Abstract]:Glaucoma is a retinal disease characterized by optic nerve atrophy and visual field defect. It is the second most common retinal disease leading to human blindness. The early symptoms of glaucoma are not obvious. Therefore, screening and diagnosis of early glaucoma will prevent the further development of glaucoma. In this paper, an algorithm for evaluating the pathogenesis of glaucoma is proposed. Then the block search algorithm is used to segment the visual disc and the cup, and the correlation between the two is analyzed. The experimental results show that the ratio of retinal nerve fiber layer to vertical cup and disc, The correlation between the optic cup area and the area ratio along the disc was 0.64n0.62 and 0.54, which proved that the thickness of retinal nerve fiber layer was closely related to the size of the cup / disc ratio in the diagnosis of glaucoma. It is of great significance to study the development trend of glaucoma.
【作者單位】： 南京理工大學(xué)計(jì)算機(jī)科學(xué)與工程學(xué)院;閩江學(xué)院福建省信息處理與智能控制重點(diǎn)實(shí)驗(yàn)室;濟(jì)南大學(xué)信息科學(xué)與工程學(xué)院;
【基金】：國(guó)家自然科學(xué)基金面上項(xiàng)目(61671242) 中央高�；究蒲袠I(yè)務(wù)費(fèi)專(zhuān)項(xiàng)資金(30920140111004) 六大人才高峰項(xiàng)目(2014-SWYY-024) 福建省信息處理與智能控制重點(diǎn)實(shí)驗(yàn)室(閩江學(xué)院)開(kāi)放課題基金(MJUKF201706)
【分類(lèi)號(hào)】：R775;TP391.41
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本文編號(hào)：1615044