發(fā)布時間：2018-05-13 16:22

  本文選題：感染性腹瀉 + 感染性腹瀉病原譜　； 參考：《中國公共衛(wèi)生》2016年06期

【摘要】：目的了解天津市感染性腹瀉病的病原構成及其表型和分子生物學等特征。方法于2007—2010年天津市區(qū)5所哨點醫(yī)院采集感染性腹瀉患者糞便樣本,檢測腹瀉病原菌。采用平板紙片擴散法檢測志賀菌14種常用抗生素耐藥性。結果樣本中病毒陽性率為35.4(164/463),腸道病原菌陽性率為41.6%(178/428)。病毒性腹瀉病原仍是諾如病毒(NV)和輪狀病毒(RV)為主,陽性率分別為14.9%(69/164)和8.2%(38/164),RV基因型以G3和P[8]為主,分別占29.5%和24.1%。細菌性腹瀉中志賀菌,宋內和福氏型,腸毒素Ⅰ、Ⅱ型多達53.5%。志賀菌對復方新諾明的耐藥率高達94.8%(55/58),對氨芐西林的耐藥率為58.6%(34/58),對諾氟沙星耐藥率為34.5%(20/58),宋內志賀菌的耐藥率更高,對上述3種抗生素的耐藥率分別為100%(31/31)、87.1%(27/31)和61.3%(19/31),多重耐藥普遍。結論天津市感染性腹瀉疾病病原學趨于復雜,志賀菌耐藥情況普遍。
[Abstract]:Objective to investigate the pathogenic composition, phenotype and molecular biology of infectious diarrhea in Tianjin. Methods fecal samples of infectious diarrhea patients were collected from 5 sentinel hospitals in Tianjin from 2007 to 2010. Drug resistance of 14 common antibiotics of Shigella was detected by plate disk diffusion method. Results the positive rate of virus and intestinal pathogenic bacteria were 35.4 / 164 / 463 and 41.6% respectively. The main pathogens of viral diarrhea were NVV (NVV) and rotavirus (RV), the positive rates were 14.9% (69 / 164) and 8.2% (P [8]), respectively. G3 and P [8] were the main genotypes of RV, accounting for 29.5% and 24.1%, respectively. Shigella, Soonet and Freund's type, enterotoxin type 鈪，

本文編號：1883933