【摘要】：目的:觀察RPH-4聯(lián)合消痔靈注射治療中度直腸內(nèi)脫垂的臨床療效。材料與方法:選取2014年12月至2016年12月在遼寧省肛腸醫(yī)院收入院的82例中度直腸內(nèi)脫垂患者,隨機(jī)分為治療組和對照組,每組41例。治療組采用RPH-4聯(lián)合消痔靈注射的手術(shù)方式,對照組采用傳統(tǒng)結(jié)扎的手術(shù)方式,觀測癥狀、直腸內(nèi)脫垂程度、術(shù)后疼痛、術(shù)后出血、手術(shù)時(shí)間、傷口愈合時(shí)間,判定療效。采用SPSS17.0進(jìn)行統(tǒng)計(jì)分析,計(jì)量資料均用均值±標(biāo)準(zhǔn)差(`x±s)表示,符合正態(tài)性分布即用t檢驗(yàn),非正態(tài)性分布即用非參數(shù)檢驗(yàn)。計(jì)數(shù)資料用卡方檢驗(yàn)。等級資料用秩和檢驗(yàn)。P0.05時(shí)無差異,無統(tǒng)計(jì)學(xué)意義;P0.05時(shí)有差異,有統(tǒng)計(jì)學(xué)意義;P0.01時(shí)有顯著性差異。結(jié)果:1.治療組、對照組治療后均能改善中度直腸內(nèi)脫垂患者的癥狀,P0.05;治療后治療組改善癥狀情況優(yōu)于對照組,P0.01。2.治療后治療組改善中度直腸內(nèi)脫垂的脫垂程度優(yōu)于對照組,P0.01。3.治療組總有效率97.56%、治愈率24.39%,對照組總有效率95.12%、治愈率9.72%,治療組臨床療效優(yōu)于對照組,P0.01。4.治療組術(shù)后疼痛較對照組明顯減輕,P0.01;治療組術(shù)后出血發(fā)生率較對照組低,P0.05;治療組手術(shù)時(shí)間、傷口愈合時(shí)間明顯較對照組縮短,P0.01。結(jié)論:1.RPH-4聯(lián)合消痔靈注射與傳統(tǒng)結(jié)扎手術(shù)均能改善中度直腸內(nèi)脫垂患者癥狀,但RPH-4聯(lián)合消痔靈注射對改善中度直腸內(nèi)脫垂患者的癥狀優(yōu)于傳統(tǒng)結(jié)扎手術(shù)。2.RPH-4聯(lián)合消痔靈注射對改善中度直腸內(nèi)脫垂的脫垂程度優(yōu)于傳統(tǒng)結(jié)扎手術(shù)。3.RPH-4聯(lián)合消痔靈注射治療中度直腸內(nèi)脫垂總有效率97.56%、治愈率24.39%,臨床療效優(yōu)于對照組。4.RPH-4聯(lián)合消痔靈注射與傳統(tǒng)結(jié)扎手術(shù)相比,患者術(shù)后痛苦小、術(shù)后出血發(fā)生率低、手術(shù)時(shí)間短、術(shù)后傷口愈合快。
[Abstract]:Objective: to observe the clinical effect of RPH-4 combined with Xiaozhiling injection in the treatment of moderate rectal prolapse. Materials and methods: from December 2014 to December 2016, 82 patients with moderate rectal prolapse were randomly divided into treatment group (n = 41) and control group (n = 41). The treatment group was treated with RPH-4 combined with Xiaozhiling injection, the control group was treated with traditional ligation, the symptoms, the degree of rectal prolapse, postoperative pain, postoperative bleeding, operation time, wound healing time were observed and the curative effect was evaluated. The statistical analysis is carried out by SPSS17.0. The measured data are expressed as mean 鹵standard deviation (`x 鹵s). The normal distribution is measured by t test, and the non-normal distribution by nonparametric test. The counting data are checked by chi-square. Grade data with rank sum test. P0.05 when there was no difference, no statistical significance; P0.05 there was difference, there was statistical significance; P0.01 had significant difference. Results: 1. Treatment group, control group can improve the symptoms of patients with moderate rectal prolapse after treatment, P0.05, treatment group after treatment is better than the control group, P0.01.2. After treatment, the degree of moderate rectal prolapse in the treatment group was better than that in the control group (P 0.01.3). The total effective rate of the treatment group was 97.56 and the cure rate was 24.39. The total effective rate of the control group was 95.12 and the cure rate was 9.72. The clinical efficacy of the treatment group was better than that of the control group (P0.01.4). The incidence of postoperative bleeding in the treatment group was lower than that in the control group (P0.05). The operation time and wound healing time in the treatment group were significantly shorter than that in the control group (P0.01). Conclusion: 1.RPH-4 combined with Xiaozhiling injection and traditional ligation can improve the symptoms of patients with moderate rectal prolapse. However, RPH-4 combined with Xiaozhiling injection was superior to traditional ligation in improving the symptoms of patients with moderate rectal prolapse, and 2.RPH-4 combined with Xiaozhiling injection was superior to traditional ligation surgery in improving the degree of prolapse of moderate rectal prolapse. The total effective rate of 3.RPH-4 combined with Xiaozhiling injection in the treatment of moderate rectal prolapse was 97.56. The cure rate was 24.39 and the clinical curative effect was better than that in the control group. Compared with the traditional ligation operation, 4.RPH-4 combined with Xiaozhiling injection had less postoperative pain, lower incidence of postoperative bleeding, shorter operative time and faster wound healing.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R266

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