【摘要】：目的：通過對撳針配合加味三仁湯治療復發(fā)性阿弗他潰瘍(濕熱蘊脾證)的臨床觀察,初步探討撳針治療RAU的增效作用及安全性。方法：60例復發(fā)性阿弗他潰瘍患者全部來自成都中醫(yī)藥大學附屬醫(yī)院口腔科門診,所有人均符合復發(fā)性阿弗他潰瘍的中醫(yī)、西醫(yī)診斷標準,同時符合中醫(yī)濕熱蘊脾的辨證標準。根據(jù)隨機分組原理把患者分為治療組和對照組各30例。對照組予以口服加味三仁湯,治療組在對照組基礎上加用撳針,設定7天為一個療程。療程結束后比較兩組治療前后西醫(yī)局部病損臨床療效(包括愈合時間、潰瘍VAS評分、潰瘍面積、潰瘍個數(shù))、總有效率、及兩組使用撳針的不良反應,并在此次治療結束后進行3個月隨訪,觀察兩組患者口腔潰瘍的復發(fā)情況。最后統(tǒng)計收集到的資料與數(shù)據(jù),并采用SPSS17.0作相應分析。結果：(1)治療前后組內局部癥狀比較：兩組在愈合時間、治療后第3天、第7天的局部癥狀(包括潰瘍VAS評分、潰瘍個數(shù))均比治療前明顯好轉(P0.05)；而潰瘍面積方面,治療組在治療后第3天、第7天均比治療前明顯好轉(P0.05)對照組僅在治療后第7天比治療前明顯好轉(P0.05)。(2)治療后組間局部癥狀比較：僅在治療后第7天潰瘍VAS評分方面,治療組明顯優(yōu)于對照組(P0.05)；其他局部癥狀改善無明顯差異(P0.05)。(3)治療后局部癥狀改善總有效率比較,兩組無明顯差異(P0.05)。(4)治療組和對照組均未見不良反應。(5)3個月復發(fā)率比較,治療組低于對照組。結論：撳針配合加味三仁湯能明顯改善復發(fā)性阿弗他潰瘍(濕熱蘊脾證)患者的口腔局部癥狀,特別是在治療后第7天對潰瘍疼痛的減輕上具有較大優(yōu)勢,并且具有延長復發(fā)時間的效果,證明了撳針針刺體穴治療復發(fā)性阿弗他潰瘍的確有一定的增效作用,是治療該病有效的輔助手段。
[Abstract]:Objective: to investigate the efficacy and safety of pressure-acupuncture combined with modified Sanren decoction in the treatment of recurrent aphthous ulcer (dampness and heat accumulation spleen syndrome). Methods Sixty patients with recurrent aphthous ulcer were all from the outpatient department of stomatology department of Chengdu University of traditional Chinese Medicine. All of them were in accordance with the diagnostic criteria of TCM and Western medicine and the standard of syndrome differentiation of dampness and heat accumulation spleen in traditional Chinese medicine. According to the principle of random grouping, the patients were divided into treatment group (n = 30) and control group (n = 30). The control group was given orally modified Sanren decoction, and the treatment group was treated with press needle on the basis of the control group and set 7 days as a course of treatment. After the course of treatment, the clinical efficacy (including healing time, ulcer VAS score, ulcer area, number of ulcers), the total effective rate and the adverse reactions of the two groups were compared before and after treatment. The recurrence of oral ulcer in the two groups was observed after 3 months follow-up. Finally, the collected data and data were collected and analyzed by SPSS17.0. Results: (1) comparison of local symptoms before and after treatment: the local symptoms (including ulcer VAS score, number of ulcers) in the two groups were significantly better than those before and after treatment (P0.05), and the area of ulcer in the two groups was better than that before treatment (P0.05). The treatment group was significantly improved on the 3rd and 7th day after treatment (P0.05). The control group only improved significantly on the 7th day after treatment (P0.05). (2). The local symptoms of the treatment group were compared only in the VAS score of ulcer on the 7th day after treatment. The treatment group was significantly better than the control group (P0.05), other local symptoms improvement had no significant difference (P0.05). (3) after treatment, there was no significant difference between the two groups (P0.05). (4) the treatment group and the control group had no adverse reactions. (5) the recurrence rate of 3 months was higher than that of the control group. The treatment group was lower than the control group. Conclusion: the combination of press acupuncture and modified Sanren decoction can obviously improve the local symptoms of oral cavity in patients with recurrent aphthous ulcer (dampness and heat accumulation spleen syndrome), especially in the relief of ulcer pain on the 7th day after treatment. It also has the effect of prolonging the time of recurrence, which proves that acupuncture at body point has a certain synergistic effect in the treatment of recurrent aphthous ulcer, and it is an effective auxiliary method for the treatment of the disease.
【學位授予單位】：成都中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R276.8

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