【摘要】：目的:觀察前列5號(hào)治療氣滯血瘀型慢性前列腺炎的臨床療效材料與方法:參照《中藥新藥臨床研究指導(dǎo)原則》的西醫(yī)診斷標(biāo)準(zhǔn)和中醫(yī)癥候診斷標(biāo)準(zhǔn),排除不符的病例,納入100例符合標(biāo)準(zhǔn)的IIIB型慢性前列腺炎和中醫(yī)癥候?yàn)闅鉁鲂吐郧傲邢傺谆颊哌M(jìn)行隨機(jī)對(duì)照臨床實(shí)驗(yàn),利用抽簽法分為治療組和對(duì)照組,每組各50例,治療組采用自擬前列5號(hào)方劑,對(duì)照組口服西藥可多華和射頻治療物理治療。兩組治療時(shí)間均為4周,并結(jié)合美國(guó)國(guó)立衛(wèi)生研究院的慢性前列腺炎癥狀指數(shù)(NIH-CPSI)、中醫(yī)癥候量化分級(jí)評(píng)分以及治療前后前列腺液中白細(xì)胞的變化,觀察并分析對(duì)比治療前后兩組療效。進(jìn)一步驗(yàn)證前列5號(hào)治療氣滯血瘀性慢性前列腺炎是較為有效、理想的治療方法。結(jié)果:經(jīng)過(guò)治療后,治療組在NIH-CPSI總分、中醫(yī)癥候量化積分優(yōu)于對(duì)照組(P0.05),在單項(xiàng)對(duì)比中下腹部墜脹或疼痛和尿后滴瀝方面,兩組間比較,有極顯著差異(P0.01);在會(huì)陰部等局部墜脹或疼痛、腰骶部、以及肛門(mén)周?chē)鷫嬅洸贿m或疼痛、尿刺痛方面,兩組間比較,有顯著差異(P0.05);而在外生殖器區(qū)墜脹或疼痛方面,兩組間比較,無(wú)明顯差異(P0.05);而在EPS中WBC變化方面治療組與對(duì)照組無(wú)明顯差異(P0.05)。結(jié)論:治療組大多數(shù)療效優(yōu)于對(duì)照組,尤其在下腹部墜脹或疼痛和尿后滴瀝方面尤為突出,在會(huì)陰部等局部墜脹或疼痛、腰骶部以及肛門(mén)周?chē)鷫嬅洸贿m或疼痛、尿刺痛方面,也有較大優(yōu)勢(shì),由此可說(shuō)明前列5號(hào)治療氣滯血瘀型的慢性前列腺炎為有效的治療方法,值得在臨床上推廣、應(yīng)用。
[Abstract]:Objective: to observe the clinical curative effect of Qianlie No. 5 on chronic prostatitis with qi stagnation and blood stasis. A randomized controlled clinical trial was conducted in 100 patients with chronic prostatitis of IIIB type and chronic prostatitis with TCM symptoms of Qi stagnation and Blood stasis. The patients were divided into treatment group and control group with 50 cases in each group by drawing lots. The treatment group was treated with Qianlie No. 5 prescription, while the control group was treated with radiofrequency therapy. The two groups were treated for 4 weeks, combined with the chronic prostatitis symptom index (NIH-CPSI) of the National Institutes of Health (NIH), the quantitative grading of TCM symptoms and the changes of leukocytes in the prostatic fluid before and after treatment. Observe and analyze the curative effect of the two groups before and after treatment. Further verify that Qianlian5 is an effective and ideal treatment for chronic prostatitis caused by stagnation of qi and blood stasis. Results: after treatment, the total score of NIH-CPSI and the quantitative score of TCM symptom in the treatment group were better than those in the control group (P0.05). There was a significant difference (P0.01) between the two groups in local distention or pain in perineum, discomfort or pain in lumbosacral region and perianus, and urinary prickly (P0.05), while in external genital area, there was a significant difference between the two groups in terms of distension or pain. There was no significant difference between the treatment group and the control group (P0.05), but there was no significant difference between the treatment group and the control group in the change of WBC in EPS (P0.05). Conclusion: most of the therapeutic effects in the treatment group are superior to those in the control group, especially in the lower abdominal distention or pain and post-urine drip, especially in the perineal region, in the lumbosacral region and around the anus, in discomfort or pain, and in the urinary prickly. It can be concluded that Qianlie No. 5 is an effective treatment method for chronic prostatitis with Qi stagnation and Blood stasis, which is worth popularizing and applying in clinic.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R277.5
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本文編號(hào)：2224044