【摘要】：目的:觀察針刺聯(lián)合中藥治療外傷性視神經(jīng)萎縮的臨床療效方法:采用平行隨機對照研究的方法,選擇符合納入標準的外傷性視神經(jīng)萎縮患者40例(46只眼),隨機分為治療組和對照組,對照組予以甲鈷胺口服,治療組在對照組的基礎(chǔ)上予以針刺配合逍遙四物湯口服。各組均以30天為一個療程進行觀察,隨訪一個月。觀察入組時、療程結(jié)束后視力、視野、F-VEP、OCT及評分的改變。結(jié)果:觀察最終病例數(shù)為40人(46只眼),實驗組及對照組各20人(23只眼)。(1)兩組基線資料比較分析:性別、年齡、眼別、病程、及各項檢查與評分之間均無差異(p0.05)。(2)各項主要指標治療前后兩組組內(nèi)比較:治療前后治療組的視力、視野改善(p0.01),對照組無顯著差異(p0.05)。治療后治療組在頭痛、眼痛、失眠減輕(p0.01);對照組頭痛、眼痛減輕(p0.05)。治療后兩組P波潛伏期縮短,振幅升高(p0.05)。治療前后平均RNFL值,治療組無顯著性差異(p0.05),對照組下降(p0.01)。結(jié)論:1.針刺聯(lián)合中藥逍遙四物湯口服能夠改善外傷性視神經(jīng)萎縮患者視力、視野,使P波潛伏期縮短、振幅升高,減緩損傷進展速度,并能緩解其頭痛、眼痛、失眠癥狀,改善其氣滯血瘀情況,與單純使用甲鈷胺口服相比較,療效更為理想。2.針刺聯(lián)合中藥逍遙四物湯口服安全性良好。
[Abstract]:Objective: to observe the clinical efficacy of acupuncture combined with traditional Chinese medicine in the treatment of traumatic optic atrophy. Forty patients (46 eyes) with traumatic optic atrophy were randomly divided into treatment group and control group. The control group was given megalomide orally, and the treatment group was treated with acupuncture combined with Xiaoyaowu decoction on the basis of the control group. All groups were observed 30 days as a course of treatment and followed up for one month. Visual acuity, visual field and F-VEP Oct were observed at the end of the course of treatment. Results: there were 40 cases (46 eyes), 20 cases (23 eyes,). (1) in the experimental group and 20 cases in the control group. The baseline data of the two groups were compared and analyzed: sex, age, eye type, course of disease, and so on. There was no difference between the two groups before and after treatment (p0. 05). (2). The visual acuity and visual field were improved before and after treatment (p0. 01), but there was no significant difference in the control group (p0. 05). After treatment, headache, eye pain and insomnia were alleviated in the treatment group (p0.01), and headache and eye pain in the control group (p0.05). After treatment, P wave latency was shortened and amplitude increased in both groups (p0.05). There was no significant difference in average RNFL before and after treatment in the treatment group and the control group (p 0.01). Conclusion 1. Acupuncture combined with Xiaoyao Siwu decoction can improve the visual acuity and visual field of the patients with traumatic optic atrophy, shorten the latency of P wave, increase the amplitude, slow down the progress of injury, and alleviate the symptoms of headache, eye pain and insomnia. The effect of improving qi stagnation and blood stasis was better than that of mecoamin alone. Acupuncture combined with Chinese medicine Xiaoyao Siwu decoction oral safety is good.
【學位授予單位】：云南中醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R276.7

【參考文獻】

相關(guān)期刊論文 前10條

1 劉銘;;注射用鼠神經(jīng)生長因子治療視神經(jīng)萎縮的療效觀察[J];中國處方藥;2017年02期

2 徐照;曾琳;王鳳洲;丁偉森;;血府逐瘀湯對外傷性視神經(jīng)損傷模型大鼠Nogo-A、GAP-43偶聯(lián)蛋白組表達的影響[J];江蘇中醫(yī)藥;2016年09期

3 羅燕;馬珊;楊金潤;劉楚玉;張昆;陳辰;;針刺聯(lián)合中藥治療外傷性視神經(jīng)病變兔的實驗研究[J];云南中醫(yī)中藥雜志;2016年01期

4 鄭云燕;;外傷性視神經(jīng)病變患者就診及預(yù)后的相關(guān)因素分析[J];中國實用神經(jīng)疾病雜志;2015年13期

5 王云鵬;;外傷性視神經(jīng)病變無光感44眼臨床觀察[J];中國實用醫(yī)藥;2015年14期

6 宋海珊;李丹;何興亮;;單唾酸四己糖神經(jīng)節(jié)苷脂治療外傷性視神經(jīng)病變[J];中國農(nóng)村衛(wèi)生;2015年08期

7 劉靜雯;秦波;;鼠神經(jīng)生長因子對外傷性視神經(jīng)病變治療作用的Meta分析[J];國際眼科雜志;2015年04期

8 龍巧燕;劉桂琴;廖海蘭;朱遠飛;黃小花;;甲基強的松龍對外傷性視神經(jīng)病變視網(wǎng)膜厚度和視網(wǎng)膜神經(jīng)節(jié)細胞的影響[J];海峽藥學;2015年03期

9 徐杰;吳衛(wèi)江;陸華;房文峰;朱愛華;;翼點外側(cè)裂入路視神經(jīng)管減壓術(shù)治療外傷性視神經(jīng)損傷17例臨床分析[J];江蘇醫(yī)藥;2014年18期

10 許新梅;;護理干預(yù)與甲基強的松龍沖擊治療外傷性視神經(jīng)病變的療效觀察[J];中國實用神經(jīng)疾病雜志;2014年17期

相關(guān)會議論文 前2條

1 吳文燦;瞿佳;王勤美;呂帆;涂云海;;內(nèi)窺鏡下經(jīng)蝶竇徑路視神經(jīng)減壓術(shù)治療外傷性視神經(jīng)病[A];第十七屆中國內(nèi)鏡醫(yī)師大會論文集[C];2007年

2 路明;李萍;;“醒腦開竅”針刺法配合頭針治療皮質(zhì)盲38例臨床療效觀察[A];中國針灸學會臨床分會第八次學術(shù)大會論文集[C];2000年

相關(guān)碩士學位論文 前1條

1 王昭迪;外傷性視神經(jīng)病的臨床與病理生理學研究[D];山東大學;2008年

，

本文編號：2217394