【摘要】：目的通過對近15年來有關功能性消化不良的中醫(yī)文獻的研讀,整理出中醫(yī)治療功能性消化不良的相關方劑,對其中包含的藥物進行分析,以求總結出功能性消化不良中醫(yī)治療的用藥特色,為當前祖國醫(yī)學治療功能性消化不良提供一定的思路借鑒。方法1研讀文獻,依照所制定的納入及排除標準選擇文獻;2根據(jù)所選文獻,整理出文獻中所運用的有效方劑;3將每首方劑中的中藥進行頻次統(tǒng)計,建立圖表數(shù)據(jù)庫;4運用統(tǒng)計軟件,將藥物按照功能、四氣五味、歸經(jīng)進行頻次分析,分析其藥物性味歸經(jīng)特點,用聚類分析、探索因子分析藥物組合,發(fā)現(xiàn)其特點,組成新的方劑。結果1所選文獻中共找出方劑111首,涉及中藥130味,其中高于平均頻次的藥物共40味,分別為黃芪、芍藥、甘草、生姜、大棗、柴胡、枳實、藿香、半夏、白術、茯苓、厚樸、陳皮、薏苡仁、豆蔻、烏藥、黃芩、澤瀉、黨參、黃連、蘇梗、丹參、沙參、延胡索、麥芽、山楂、神曲、香附、枳殼、木香、砂仁、郁金、佛手、山藥、梔子、當歸、石菖蒲、萊菔子、干姜、人參。2上述藥物進行功能、四氣五味、歸經(jīng)分析,藥物功能以疏肝理氣、健脾補虛、化濕和中類藥物為最多,四氣五味中溫(22)、寒(9)、平(7)性藥物和辛(21)、甘(15)、苦(19)類藥物居多。藥物歸經(jīng)中以脾經(jīng)(33)、胃經(jīng)(23)、肺經(jīng)(17)、心經(jīng)(10)、肝經(jīng)(9)為多。3通過探索性因子分析及聚類分析最終得到3個藥物的組方,分別是:F1:茯苓、白術、黨參、木香、生姜、大棗。F2:白芍、柴胡、枳殼、香附、陳皮。F3:黃芩、干姜、人參、半夏、甘草、枳實、黃連、砂仁、厚樸。結論1現(xiàn)代中醫(yī)治療功能性消化不良重視溫補,注重從調節(jié)脾胃氣機升降著手用藥;2現(xiàn)代中醫(yī)治療功能性消化不良與古代中醫(yī)治療時側重“健脾補虛”的不同之處在于,更加注重疏肝理氣,解郁補虛類藥物的使用。
[Abstract]:Objective to study the Chinese medicine literature on functional dyspepsia in recent 15 years, and to sort out the relevant prescriptions for the treatment of functional dyspepsia, and to analyze the drugs contained therein. In order to sum up the characteristics of traditional Chinese medicine treatment of functional dyspepsia, for the current medical treatment of functional dyspepsia to provide some ideas for reference. Methods 1 study the literature, select the literature according to the standard of inclusion and exclusion. According to the selected literature, sort out the effective prescription used in the literature and make statistics on the frequency of the Chinese medicine in each prescription. A chart database was set up and statistical software was used to analyze the frequency of the medicine according to its function, four qi and five flavors, and to analyze the characteristic of its characteristic flavor and meridian. Cluster analysis was used to explore the combination of drugs by factor analysis, and its characteristics were found. Form a new prescription. Results 1A total of 111 prescriptions involving 130 kinds of traditional Chinese medicine were found in the selected literature, 40 of which were above the average frequency. They were astragalus, paeoniflorin, liquorice, ginger, jujube, Bupleurum, Fructus Aurantii, patchouli, Pinellia ternata, Atractylodes macrocephalae, Poria cocos, and Magnolia officinalis. Chenpi, Coix seed, nutmeg, black medicine, Radix Scutellariae, Radix Alismatis, Codonopsis, Coptidis, Pulp, Salvia miltiorrhiza, Radix Salviae, Rhizoma Corydalis, Malt, Hawthorn, Divine Comedy, Fraxinus, Fructus Aurantii, Amur, Tulip, Buddha's hand, yam, Gardenia, Angelica sinensis, Acorus calamus, semen Raphani, Rhizoma Raphani, Ginger, Ginseng .2 the above-mentioned drugs for function, four Qi five flavor, analysis of the meridian, drug function in soothing liver and regulating qi, invigorating spleen and tonifying deficiency, removing dampness and middle class drugs are the most. Most of the drugs were mild (22), cold (9), Ping (7) and Xin (21), Gan (15) and bitter (19). In the meridian of medicine, spleen meridian (33), stomach meridian (23), lung meridian (17), heart meridian (10), liver meridian (9) were used to obtain three drug formulations by exploratory factor analysis and cluster analysis. They were: Tuckahoe, Atractylodes macrocephala, Codonopsis pilosula, Amur, Ginger, Jujube. F2: Paeoniae Alba. Radix Bupleurum, Fructus Aurantii, Fructus Aurantii, Pericarpium F3: Scutellaria, Ginger, Ginseng, Pinellia ternata, liquorice, Fructus Aurantii, Coptis chinensis, Amomum, Magnolia officinalis. Conclusion (1) in the treatment of functional dyspepsia, modern Chinese medicine pays more attention to temperature supplement, and to regulating the rise and fall of spleen and stomach qi. 2 the difference between modern Chinese medicine treatment of functional dyspepsia and that of ancient Chinese medicine is that it is different from that of "strengthening spleen and reinforcing deficiency". Pay more attention to soothing the liver and regulating qi, relieving depression and tonifying the use of drugs.
【學位授予單位】：華北理工大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R259

【參考文獻】

相關期刊論文 前10條

1 李任鋒;;四君子湯加減治療功能性消化不良68例[J];中國醫(yī)藥指南;2016年23期

2 陳滿濤;王力紅;苑曉潔;;觀察中醫(yī)經(jīng)驗方加減治療功能性消化不良的臨床療效[J];世界最新醫(yī)學信息文摘;2016年58期

3 魯小艷;喻斌;;加味柴胡疏肝散治療功能性消化不良(肝郁氣滯證)臨床療效觀察[J];湖南中醫(yī)藥大學學報;2016年04期

4 甘德春;;中醫(yī)辨證治療功能性消化不良的對比研究[J];中國醫(yī)藥導報;2015年10期

5 徐亞蘭;鮑曉東;;論徐靈胎“治病必分經(jīng)絡臟腑”思想及其在《洄溪醫(yī)案》中的運用[J];山西中醫(yī)學院學報;2015年01期

6 劉燕;王春艷;劉敏;高紅艷;王宜;;功能性消化不良患者焦慮抑郁情緒現(xiàn)狀和影響因素調查研究[J];河北醫(yī)學;2013年07期

7 張芬;;功能性消化不良的中醫(yī)辨證治療[J];現(xiàn)代診斷與治療;2013年05期

8 馬海麗;朱瑩;;柴胡疏肝散治療氣郁質功能性消化不良30例[J];湖南中醫(yī)雜志;2013年01期

9 張軼鶴;;功能性消化不良的中西醫(yī)治療效果分析[J];當代醫(yī)學;2012年26期

10 劉運至;魏立仁;;柴枳平肝湯治療功能性消化不良肝胃不和證的臨床觀察[J];中醫(yī)藥導報;2012年02期

相關會議論文 前1條

1 張聲生;汪紅兵;;消化不良中醫(yī)診療共識意見[A];中華中醫(yī)藥學會脾胃病分會第二十三次全國脾胃病學術交流會論文匯編[C];2011年

相關博士學位論文 前4條

1 呂林;中醫(yī)健脾法治療痞滿（功能性消化不良）臨床與實驗觀察[D];廣州中醫(yī)藥大學;2014年

2 張望;四君子湯加味治療脾虛型FD的臨床觀察及MLCK機制探討[D];廣州中醫(yī)藥大學;2014年

3 郭文娟;功能性消化不良癥狀與機制的研究[D];北京協(xié)和醫(yī)學院;2013年

4 鄺麗華;梁乃津教授辨治脾胃病的學術經(jīng)驗整理及其應用研究[D];廣州中醫(yī)藥大學;2009年

相關碩士學位論文 前4條

1 蔡瑞云;半夏瀉心湯加減治療寒熱錯雜型功能性消化不良的療效觀察[D];南京中醫(yī)藥大學;2016年

2 王建明;江楊清教授治療脾胃病臨床經(jīng)驗總結及脾胃方治療脾胃氣虛型功能性消化不良臨床觀察[D];南京中醫(yī)藥大學;2015年

3 易維恒;半夏瀉心湯加減方治療功能性消化不良寒熱錯雜證的臨床觀察[D];湖北中醫(yī)藥大學;2015年

4 閆石;《景岳全書》脾胃學術思想研究[D];山東中醫(yī)藥大學;2011年

，

本文編號：2180957