【摘要】：目的:通過(guò)對(duì)心膽氣虛型失眠的病因病機(jī)的探索,觀察加味安神定志顆粒治療心膽氣虛型失眠患者的臨床療效,驗(yàn)證加味安神定志顆粒治療失眠(心膽氣虛型)的有效性。方法:本次研究對(duì)象于2015年2月至2016年2月就診于河南中醫(yī)藥大學(xué)第一附屬醫(yī)院腦病三區(qū)門(mén)診的失眠患者中篩選,將符合本次課題選取標(biāo)準(zhǔn)的60例心膽氣虛型失眠患者,隨機(jī)分為治療組30例,對(duì)照組30例。對(duì)照組30例給予右佐匹克隆片睡前3mg口服,治療組在對(duì)照組的基礎(chǔ)上口服加味安神定志顆粒每日1劑,治療組與對(duì)照組均服藥4周。兩組患者分別于治療前后進(jìn)行一次中醫(yī)癥候及匹茲堡睡眠質(zhì)量指數(shù)(PQSI)評(píng)分,運(yùn)用統(tǒng)計(jì)學(xué)對(duì)得出的數(shù)據(jù)進(jìn)行分析來(lái)評(píng)價(jià)本研究臨床療效。結(jié)果:對(duì)記錄的數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析,治療前兩組患者性別、年齡、病程、中醫(yī)癥候及PQSI評(píng)分均無(wú)顯著性差異(P0.05),提示具有可比性。治療后統(tǒng)計(jì)結(jié)果提示治療組在降低PSQI評(píng)分及中醫(yī)癥候評(píng)分,改善患者睡眠質(zhì)量、日間功能障礙方面優(yōu)于對(duì)照組(P0.05)。治療組總有效率為93.33%,對(duì)照組為83.33%,對(duì)比具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:加味安神定志顆粒聯(lián)合右佐匹克隆片治療失眠(心膽氣虛型)具有較好的臨床效果,在改善患者睡眠質(zhì)量、日間功能障礙及中醫(yī)癥候方面提示明顯優(yōu)于單用右佐匹克隆片組。
[Abstract]:Objective: to explore the etiology and pathogenesis of insomnia of heart and gallbladder qi deficiency, observe the clinical effect of Jiawei Anshen Dingzhi granule in treating insomnia of heart and gallbladder qi deficiency, and verify the effectiveness of Jiawei Anshen Dingzhi granule in treating insomnia (heart and gallbladder qi deficiency). Methods: from February 2015 to February 2016, 60 patients with insomnia of heart and gallbladder qi deficiency type were selected from the outpatient clinic of the first affiliated Hospital of Henan University of traditional Chinese Medicine in the third District of Encephalopathy, which were selected from February 2015 to February 2016. They were randomly divided into treatment group (n = 30) and control group (n = 30). The control group (30 cases) were given 3mg before bedtime, and the treatment group took 1 dose of Jiawei Anshen Dingzhi granule daily on the basis of the control group. The treatment group and the control group were treated for 4 weeks. Two groups of patients before and after the treatment of TCM symptoms and Pittsburgh Sleep quality Index (PQSI) score statistical analysis of the data obtained to evaluate the clinical efficacy of this study. Results: there were no significant differences in gender, age, course of disease, TCM symptom and PQSI score between the two groups before treatment (P0.05). The statistical results showed that the treatment group was superior to the control group in reducing PSQI score and TCM symptom score, improving patients' sleep quality and daytime dysfunction (P0.05). The total effective rate was 93.33 in the treatment group and 83.33 in the control group. The comparison was statistically significant (P0.05). Conclusion: Jiawei Anshen Dingzhi granule combined with right zopicone tablet has good clinical effect in treating insomnia (heart and gallbladder qi deficiency type) and can improve the sleeping quality of patients. The results showed that the daytime dysfunction and TCM symptoms were better than that of RZP alone.
【學(xué)位授予單位】：河南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R256.23

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