本文選題：酒精性肝硬化 + 中醫(yī)證型　； 參考：《遼寧中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:通過(guò)對(duì)酒精性肝硬化患者客觀指標(biāo)的總結(jié)歸納,了解其證型分布規(guī)律,分析該病中醫(yī)證型與相關(guān)指標(biāo)的關(guān)系,為酒精性肝硬化的中醫(yī)辯證提供客觀依據(jù)。方法:查閱2005年10月-2015年9月期間遼寧中醫(yī)藥大學(xué)附屬醫(yī)院肝病門診的病例,參照納入及排除標(biāo)準(zhǔn)篩選病例,將符合標(biāo)準(zhǔn)的233例病例作為研究對(duì)象進(jìn)行回顧性分析,記錄入選患者的姓名、性別、年齡、文化程度、每日攝入乙醇量、飲酒年限、中醫(yī)辨證分型、主要癥狀、陽(yáng)性體征、并發(fā)癥,以及肝功能、凝血功能等相關(guān)指標(biāo),應(yīng)用SPSS19.0統(tǒng)計(jì)軟件對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析,以探討中醫(yī)證型與客觀指標(biāo)之間的相關(guān)性。結(jié)果:1.中醫(yī)證型分布:將233例酒精性肝硬化患者辨證分為6型,其中以濕熱蘊(yùn)結(jié)證及脾陽(yáng)不運(yùn)證所占比例較高,分別約占31.33%和23.18%,其他證型均占20%以下。2.中醫(yī)證型與客觀指標(biāo)的相關(guān)性:中醫(yī)證型與年齡、每日攝入乙醇量、飲酒年限、ALB、A/G、AST、AST/ALT、ALP、GGT、PT、APTT、FIB均有相關(guān)性,其中各證型間ALB、AST/ALT、ALP、GGT、PT比較有顯著差異(P0.01)。肝郁脾虛證患者的年齡均值最小,飲酒年限最短,ALB、FIB均值最高,PT、APTT均值最低;濕熱蘊(yùn)結(jié)證患者每日攝入乙醇量最高,AST/ALT、ALP均值最高;肝腎陰虛證患者飲酒年限最長(zhǎng),ALB、A/G、AST均值最低;瘀血阻絡(luò)證患者AST均值最高;脾陽(yáng)不運(yùn)證患者GGT均值最低。結(jié)論:1.酒精性肝硬化患者中醫(yī)證型與每日攝入乙醇量及飲酒年限直接相關(guān)。2.酒精性肝硬化患者中醫(yī)證型與ALB、AST/ALT、ALP、GGT、PT密切相關(guān)。3.酒精性肝硬化患者以濕熱蘊(yùn)結(jié)證最為常見(jiàn)。
[Abstract]:Objective: to summarize the objective indexes of alcoholic cirrhosis patients, understand the distribution of syndrome types, and analyze the relationship between TCM syndromes and related indexes of alcoholic cirrhosis, so as to provide objective basis for TCM dialectical of alcoholic cirrhosis. Methods: from October 2005 to September 2015, the cases of liver diseases in affiliated hospitals of Liaoning University of traditional Chinese Medicine were reviewed, and 233 cases that met the criteria were retrospectively analyzed according to the inclusion and exclusion criteria. The names, sex, age, education level, daily alcohol intake, drinking years, TCM syndrome differentiation, main symptoms, positive signs, complications, liver function and coagulation function were recorded. The statistical software SPSS 19.0 was used to analyze the data in order to explore the correlation between TCM syndromes and objective indexes. The result is 1: 1. The distribution of TCM syndromes: 233 cases of alcoholic liver cirrhosis were divided into 6 types, of which the proportion of damp-heat accumulation syndrome and spleen yang non-transport syndrome was higher, accounting for 31.33% and 23.18% respectively, and the other syndrome types were all less than 20% .2. Correlation between TCM syndromes and objective indexes: there was a significant correlation between TCM syndromes and age, daily alcohol intake, alcohol consumption, ALBAST / AST / alt / AGT / PTTTFIB, among which there was a significant difference in ALBAST / alt / ALPGGTPT among different syndromes (P0.01). The patients with liver stagnation and spleen deficiency syndrome had the lowest mean age, the shortest drinking years and the highest mean value of ALB FIB and the lowest mean of PTT APTT; the highest daily intake of ethanol in the patients with damp-heat accumulation syndrome and the highest mean value of AST / ALT ALP; the longest drinking years in the patients with liver and kidney yin deficiency syndrome; The mean value of AST was the highest in patients with stagnation of blood and obstruction of collaterals, and the lowest in patients with syndrome of spleen yang. Conclusion 1. The TCM syndromes of alcoholic cirrhosis patients were directly related to alcohol intake and drinking duration. 2. 2. The TCM syndromes of alcoholic cirrhosis patients were closely related with ALBAST / alt / ALP GGTT PT. 3. The syndrome of dampness and heat accumulation is the most common in alcoholic cirrhosis.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259

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