本文選題：慢性乙型肝炎 + 脂肪肝�。� 參考：《遼寧中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:通過對肝臟內部不同病變患者及健康志愿者,肝區(qū)期門穴彩色多普勒超聲定點檢測的穴下解剖組織結構的差異性比較研究,從解剖組織形態(tài)學角度探索肝區(qū)內期門穴反映肝臟病理變化的生物醫(yī)學基礎。為論證肝募期門反映病癥效應及其相關的特定穴理論的科學性提供科學依據。材料與方法:對象及分組:收集病變部位在肝臟的慢乙肝、肝硬化、脂肪肝患者病例114例,健康志愿者資料45例。疾病組采用分層分組的方法,分為慢乙肝組、肝硬化組和脂肪肝組。指標檢測及方法:采用低頻彩色超聲定點垂直超聲檢測方法,檢測在肝區(qū)的期門穴下解剖組織結構,以彩超視野中點為原點,記錄距離原點最近的肝內組織形態(tài)結構,總結并匯總數據。分別進行肝臟不同疾病狀態(tài)受試者,解剖組織結構檢出率的組間配對檢驗,以健康對照組為基準,探討期門穴定點超聲所揭示的HBV感染不同病理階段、脂肪肝的肝臟內部組織形態(tài)學的病理變化規(guī)律及特征。使用統(tǒng)計學分析軟件SPSS17.0對采集的數據進行分析,均值用(?x±s)表示,如檢驗結果P0.05說明具有統(tǒng)計學意義。結果:1.健康組與肝內病變組配對檢驗結果(1)慢乙肝、肝硬化肝組織檢出率低于健康組,門靜脈血管檢出率高于健康組,P0.05(2)脂肪肝矢狀部檢出率高于健康組,P0.05;2.肝內病變組間配對檢驗結果(1)慢乙肝門靜脈檢出率高于肝硬化、脂肪肝,P0.05,(2)慢乙肝、肝硬化肝組織檢出率小于脂肪肝,P0.05,結論:1.期門穴對應的肝臟內部解剖組織結構的差異性是影響期門穴反映病癥效應特異性的生物醫(yī)學基礎。2.慢乙肝、肝硬化不同病理階段門靜脈干支、矢狀部檢出率增高,符合HBV感染之后,會出現肝組織纖維化導致門靜脈高壓,以及有肝臟體積變小的病理演變規(guī)律。體現了“肝以血為用”中醫(yī)理論的科學性。
[Abstract]:Objective: to compare the differences of anatomical tissue structure of subpoints detected by color Doppler ultrasound at portal acupoints in different liver lesions and healthy volunteers. From the angle of anatomical histomorphology, we explored the biomedical basis of portal point in liver region to reflect the pathological changes of liver. It provides a scientific basis for demonstrating the effect of liver disease and its related theory of specific acupoints. Materials and methods: 114 patients with chronic hepatitis B, liver cirrhosis and fatty liver were collected and 45 healthy volunteers were collected. The disease group was divided into chronic hepatitis B group, liver cirrhosis group and fatty liver group. Indexes and methods: low frequency color ultrasound was used to detect the anatomical structure of liver tissue under the point of stage gate. The middle point of the field of vision of color Doppler ultrasound was used as the origin to record the structure of the liver tissue nearest to the origin. Summarize and summarize data. The detection rate of anatomical tissue structure of different liver diseases in subjects was tested by paired group, and the pathological stages of HBV infection revealed by sentinel ultrasound at portal acupoint were studied by using the healthy control group as the reference. Pathological changes and characteristics of liver histomorphology in fatty liver. The statistical analysis software SPSS 17.0 was used to analyze the collected data, the mean value was expressed by X 鹵s, such as the test results P0.05 showed statistical significance. The result is 1: 1. 1) the detection rate of chronic hepatitis B and liver cirrhosis in liver tissue was lower than that in healthy group, and the detection rate of portal vein was higher than that in healthy group (P0.05 / 2) the sagittal detection rate of fatty liver was higher than that in healthy group. The detection rate of chronic hepatitis B in portal vein was higher than that in liver cirrhosis, and that in fatty liver tissue was lower than that in fatty liver tissue. The difference of the anatomical structure of the liver corresponding to the point gate is the biomedical basis that affects the specificity of the disease effect at the point gate. The detection rate of portal vein dry branch in different pathological stages of chronic hepatitis B and liver cirrhosis was higher than that in sagittal part, which was consistent with the pathological evolution of hepatic fibrosis and portal hypertension after HBV infection. It reflects the scientific nature of traditional Chinese medicine theory of "liver is used by blood".
【學位授予單位】：遼寧中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R246.1

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