基于證素辨證分析對原發(fā)性骨質疏松癥證型分布的研究
本文選題:原發(fā)性骨質疏松癥 + 病機; 參考:《山東中醫(yī)藥大學》2016年碩士論文
【摘要】:研究目的:通過證素辨證方法對原發(fā)性骨質疏松癥(POP)進行辨證分析,探討其中醫(yī)證型分布特點,并分析不同證型與患者的一般情況、發(fā)病特點及臨床指標的相關性。從而為本病中醫(yī)分型客觀化尋找依據(jù),有利于全面探析其證治規(guī)律,為POP的早期診斷、分型、確立治法、選方用藥提供理論支持。研究方法:采用統(tǒng)一的信息收集表對80例原發(fā)性骨質疏松癥患者的證素信息等資料進行采集,應用證素辨證研究方法,分析原發(fā)性骨質疏松癥中醫(yī)證型分布特點,利用統(tǒng)計學方法計算中醫(yī)證型與各發(fā)病因素的相關性,并對其特點進行總結歸納。結果:1.病位證素以腎最多見,其次是脾、肝、筋骨、心、經絡。病性證素中,虛證證素以陽虛最多見,其次是陰虛、氣虛、血虛、精虧;實證證素出現(xiàn)次數(shù)最多的是血瘀,其余依次為氣滯、寒、熱、痰、濕。2.常見中醫(yī)證型按出現(xiàn)頻次排序前5位依次為:肝腎陰虛、脾腎陽虛、氣虛血瘀、腎陽虛、筋骨痹阻。3.不同證型與發(fā)病因素的相關性:(1)各證型中性別分布無統(tǒng)計學差異(P0.05);骨密度分布無統(tǒng)計學差異(P0.05);身高、體重、BMI分布無統(tǒng)計學差異(P0.05)。(2)骨痛癥狀在不同證型中的分布有統(tǒng)計學差異(P0.05)。氣虛血瘀組和筋骨痹阻組均與其他3組存在統(tǒng)計學差異(p0.05),而氣虛血瘀組與筋骨痹阻組之間無統(tǒng)計學差異(p0.05)。(3)有否脊柱變形在不同證型中的分布無統(tǒng)計學差異(P0.05)。(4)骨折發(fā)生率在不同證型中的分布中有顯著統(tǒng)計學差異(P0.01)。氣虛血瘀組與其余4組存在統(tǒng)計學差異(P0.05)(5)骨質疏松癥有否合并高血壓在各證型中的分布無統(tǒng)計學差異(P0.05)。(6)骨質疏松癥有否合并冠心病在各證型中的分布有顯著統(tǒng)計學差異(P0.01)。氣虛血瘀組與筋骨痹阻組、肝腎陰虛組、脾腎陽虛組存在顯著性差異(P0.01),與腎陽虛組存在統(tǒng)計學差異(P0.05)。結論:1.原發(fā)性骨質疏松癥病位主要在腎,多或可涉及肝、脾。病理性質虛中夾實,陽、陰、氣虛均較為多見。實性病理因素以血瘀、氣滯為主。2.筋骨痹阻證多出現(xiàn)骨痛癥狀。氣虛血瘀證多發(fā)骨痛、骨折,多合并冠心病。3.研究結果提示原發(fā)性骨質疏松癥的治療應以補腎為主,兼顧肝、脾,重視活血化瘀法的應用。對于氣虛血瘀型患者強調活血止痛,預防骨折。
[Abstract]:Objective: to analyze the syndrome differentiation of primary osteoporosis (POP) by syndrome element differentiation, to discuss the distribution of TCM syndrome types, and to analyze the relationship between different syndromes and patients' general situation, disease characteristics and clinical indexes. So as to find the basis for the objective classification of TCM, which is conducive to the comprehensive analysis of the law of syndrome and treatment, for the early diagnosis of POP, typing, the establishment of treatment methods, the choice of prescription to provide theoretical support. Methods: the information of syndromes of 80 patients with primary osteoporosis was collected by using a unified information collection table, and the distribution characteristics of TCM syndromes of primary osteoporosis were analyzed by syndrome differentiation. The correlation between TCM syndromes and various factors was calculated by statistical method, and its characteristics were summarized. The result is 1: 1. Kidney is the most common syndrome, followed by spleen, liver, bones, heart, meridian. Among the factors of disease syndrome, deficiency syndrome is characterized by deficiency of yang, followed by deficiency of yin, deficiency of qi, deficiency of blood and deficiency of essence; the most frequent occurrence of syndrome factor is blood stasis, and the others are stagnation of qi, cold, heat, phlegm, dampness, and dampness. The most common TCM syndromes in order of frequency are liver and kidney yin deficiency, spleen and kidney yang deficiency, qi deficiency and blood stasis, kidney yang deficiency, and stagnation of muscles and bones. There was no significant difference in sex distribution among different syndrome types (P 0.05); there was no significant difference in bone mineral density (P 0.05); there was no significant difference in the distribution of height, body weight and BMI; there was no significant difference in the distribution of bone pain symptoms in different syndromes (P 0.05. 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05; P 0. 05); There was statistical difference between Qi deficiency and blood stasis group and the other three groups, but there was no significant difference between Qi deficiency and blood stasis group and bone obstruction group. (P 0.05) there was no significant difference in the distribution of spinal deformity in different syndromes. There was significant difference in the distribution of incidence rate among different syndromes (P 0.01). There was statistical difference between the Qi deficiency and blood stasis group and the other four groups (P < 0.05). There was no significant difference in the distribution of osteoporosis with hypertension in each syndrome type. There was no significant difference in the distribution of osteoporosis with coronary heart disease (P 0.01). There was significant difference between Qi deficiency and blood stasis group and stagnation group, liver and kidney yin deficiency group, spleen and kidney yang deficiency group (P 0.01), and there was statistical difference between Qi deficiency group and kidney yang deficiency group (P 0.05). Conclusion 1. Primary osteoporosis is mainly located in the kidney, more or may involve liver, spleen. The pathological nature of deficiency in the inclusion of consolidation, Yang, Yin, Qi deficiency are more common. Solid pathological factors were blood stasis and qi stagnation. The symptoms of bone pain are often found in the syndrome of arthralgia of the muscles and bones. Qi deficiency and blood stasis syndrome multiple bone pain, fracture, more complicated with coronary heart disease. 3. The results suggest that primary osteoporosis should be treated mainly by tonifying the kidney, taking into account the liver and spleen, and paying attention to the application of the method of promoting blood circulation and removing blood stasis. For Qi deficiency and blood stasis type patients emphasis on promoting blood circulation to relieve pain and prevent fracture.
【學位授予單位】:山東中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2016
【分類號】:R259
【相似文獻】
相關期刊論文 前10條
1 劉燦康;;氣虛血瘀是促使衰老的因素[J];中醫(yī)臨床與保健;1992年04期
2 陸孝成,周清安,王至婉,李小黎,侯秀娟;氣虛血瘀在老年人缺血性腦血管病中的地位及意義[J];河南中醫(yī);2003年01期
3 邵致格,胡曼菁,王長松;現(xiàn)代人群的體質病理學特征:氣虛血瘀[J];醫(yī)學與哲學;2005年04期
4 王剛;曲敬來;高雪;唐啟盛;畢旭偉;于翠萍;穆欣;孟維濱;薛桂榮;;肺氣虛血瘀原因的探討和川芎嗪對其防治作用的研究(摘要)[J];中西醫(yī)結合雜志;1988年10期
5 劉樹新;魏慶宇;徐家升;;氣虛血瘀是糖尿病發(fā)病的重要病理基礎[J];實用中醫(yī)內科雜志;1993年01期
6 方潤龍;;冠心病與中醫(yī)氣虛血瘀關系探討[J];北方藥學;2012年03期
7 闞俊明;王東海;金東明;;金東明運用氣虛血瘀病機治療心系疾病經驗介紹[J];新中醫(yī);2014年05期
8 朱飛鵬,馮素云;從氣虛血瘀水停論治充血性心力衰竭近況[J];河南中醫(yī)藥學刊;2000年01期
9 張文娟;氣虛血瘀與缺血性卒中[J];中國醫(yī)藥學報;2002年09期
10 楊金龍;李曉;;氣虛血瘀與冠心病關系初探[J];河南中醫(yī);2012年06期
相關會議論文 前6條
1 崔曉萍;;論產后出血氣虛血瘀相關性[A];全國中西醫(yī)結合生殖健康學術研討會論文及摘要集[C];2004年
2 孫學剛;;以hs-CRP作為動脈粥樣硬化氣虛血瘀病機的標志物[A];中國中西醫(yī)結合學會第五屆基礎理論研究專業(yè)委員會學術研討會論文集[C];2006年
3 王德旭;;以陰虛、氣虛立論治療帶狀皰疹后遺神經痛療效觀察[A];2014全國中西醫(yī)結合皮膚性病學術年會論文匯編[C];2014年
4 王武華;宋曉鴻;;從虛、瘀、痰辨治高原地區(qū)肺心病體會[A];全國第六屆中西醫(yī)結合呼吸病學術研討會論文匯編[C];2002年
5 王擁軍;施杞;江建春;卞琴;梁倩倩;李晨光;周泉;崔學軍;盧盛;周重建;;益氣化瘀補腎方治療氣虛血瘀腎虧型頸椎病的機理研究[A];中國康復醫(yī)學會頸椎病專業(yè)委員會第十次學術年會論文匯編[C];2008年
6 彭敏;諶劍飛;張艷玲;;中風中經絡氣虛血瘀挾痰型血漿NPY含量變化[A];第四次全國中西醫(yī)結合神經系統(tǒng)疾病學術研討會論文集[C];2002年
相關重要報紙文章 前6條
1 山西平遙 王金亮;氣虛血瘀臨證之感悟[N];上海中醫(yī)藥報;2013年
2 遼寧中醫(yī)藥大學附屬醫(yī)院 張明雪邋車紅花 常艷鵬;從氣虛血瘀探討冠心病發(fā)病機制[N];中國中醫(yī)藥報;2007年
3 王成龍 王磊;補元氣與心腦康復[N];健康報;2007年
4 本報評論員 廖水南;“神醫(yī)”為什么偏愛中醫(yī)?[N];重慶商報;2012年
5 李林青;活血化瘀能有效控制糖尿病并發(fā)癥[N];中國中醫(yī)藥報;2007年
6 康健;測測看,長壽潛能你有嗎?[N];健康時報;2009年
相關博士學位論文 前2條
1 扈新剛;氣虛血瘀大鼠模型表征及生物學基礎相關研究[D];北京中醫(yī)藥大學;2007年
2 劉雅;氣虛致瘀證本質現(xiàn)代醫(yī)學表征及分子基礎初探[D];第三軍醫(yī)大學;2008年
相關碩士學位論文 前10條
1 韓婧;熄風止悸湯治療陣發(fā)性心房纖顫(氣虛血瘀,風動心脈證)的臨床研究[D];長春中醫(yī)藥大學;2015年
2 隋晨暉;基于證素辨證分析對原發(fā)性骨質疏松癥證型分布的研究[D];山東中醫(yī)藥大學;2016年
3 曾建雄;氣虛血瘀的理論研究[D];福建中醫(yī)學院;2009年
4 崔云林;冠心病合并高血壓患者中醫(yī)體質(本虛)證素分布規(guī)律研究[D];南京中醫(yī)藥大學;2012年
5 郭靈祥;118例糖調節(jié)受損狀態(tài)人群的中醫(yī)證型分析[D];福建中醫(yī)學院;2007年
6 馬偉忠;益氣活血法治療特發(fā)性局灶節(jié)段性腎小球硬化的臨床研究[D];廣州中醫(yī)藥大學;2008年
7 黃容巖;冠心病穩(wěn)定型心絞痛(氣虛血瘀,痰濁阻絡證)治療方案的研究[D];長春中醫(yī)藥大學;2013年
8 金煜;中藥強心方干預缺血性心肌病發(fā)作期氣虛血瘀水停證的臨床研究[D];長春中醫(yī)藥大學;2010年
9 蔡敏;早發(fā)不穩(wěn)定性心絞痛的證候特征及中醫(yī)藥對動物易損斑塊的穩(wěn)定作用[D];首都醫(yī)科大學;2013年
10 郭南京;120例2型糖尿病合并高血壓患者中醫(yī)證候分析[D];福建中醫(yī)學院;2009年
,本文編號:1972943
本文鏈接:http://www.sikaile.net/zhongyixuelunwen/1972943.html