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健脾瀉濁湯治療高脂血癥(痰濁阻遏型)的臨床療效觀察

發(fā)布時(shí)間:2018-06-02 01:05

  本文選題:健脾瀉濁湯 + 高脂血癥 ; 參考:《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文


【摘要】:目的:觀察健脾瀉濁湯治療痰濁阻遏型高脂血癥的臨床療效。方法:本次研究從黑龍江中醫(yī)藥大學(xué)附屬第一醫(yī)院心內(nèi)科門診共篩選出符合診斷標(biāo)準(zhǔn)的患者64例,按照隨機(jī)數(shù)字表將患者分成觀察組和對(duì)照組,每組各32例。其中對(duì)照組服用血脂康膠囊治療,觀察組服用健脾瀉濁湯治療。3個(gè)月后觀察患者治療前后血脂四項(xiàng)指標(biāo)(TC、TG、LDL-C、HDL-C)、血脂治療總療效以及中醫(yī)癥候總療效和中醫(yī)癥候積分的變化。詳細(xì)記錄各項(xiàng)觀察指標(biāo)后進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:1.兩組中醫(yī)癥候療效總有效率分別為90.3%(觀察組)和67.7%(對(duì)照組),組間比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);兩組中醫(yī)癥候積分分別下降至 5.54±3.85mmol/L(觀察組)和 9.09土 4.74mmol/L(對(duì)照組),組間比較差異極有統(tǒng)計(jì)學(xué)意義(P<0.01)。2.兩組血脂治療總有效率分別為87.0%(觀察組)和80.6%(對(duì)照組),組間對(duì)比差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05);兩組血脂指標(biāo)(TC、TG、LDL-C、HDL-C)治療后均較前改善,前后對(duì)比差異均具有統(tǒng)計(jì)學(xué)意義(P<0.05);治療后兩組間TC、LDL-C、HDL-C水平兩兩對(duì)比差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),治療后觀察組TG的水平下降為1.96±0.21 mmol/L,對(duì)照組TG的水平下降為2.20士 0.30 mmol/L,兩組對(duì)比差異極有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論:1.健脾瀉濁湯能夠有效改善痰濁阻遏型高脂血癥患者血脂水平。2.健脾瀉濁湯能夠明顯改善痰濁阻遏型高脂血癥患者中醫(yī)癥候。
[Abstract]:Objective: to observe the clinical effect of Jianpi Xiezhuo decoction in treating hyperlipidemia of phlegm and turbid repressor type. Methods: a total of 64 patients were selected from the Department of Cardiology of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. According to the random digital table, the patients were divided into observation group and control group with 32 cases in each group. The control group was treated with Xuezhikang capsule and the observation group was treated with Jianpi Xieshuo decoction. After 3 months of treatment, the changes of four indexes of blood lipids were observed before and after treatment. The observation indexes were recorded in detail and analyzed statistically. The result is 1: 1. The total effective rates of TCM symptoms in the two groups were 90.3 (observation group) and 67.7 (control group, the difference was statistically significant P < 0.05), and the score of TCM symptom in the two groups decreased to 5.54 鹵3.85 mmol / L (observation group) and 9.09 鹵4.74 mmol / L (control group, respectively). The difference between the two groups was statistically significant (P < 0.01). The total effective rates of blood lipid therapy in the two groups were 87.0 and 80.6 respectively (the control group), there was no significant difference between the two groups (P > 0.05). After treatment, there was no significant difference in the level of HDL-C between the two groups. After treatment, the level of TG in the observation group decreased to 1.96 鹵0.21 mmol / L, and the level of TG in the control group decreased to 2.20 鹵0.30 mmol / L, respectively. There was no significant difference in the level of HDL-C between the two groups after treatment (P < 0.05), and the level of TG in the observation group decreased to 1.96 鹵0.21 mmol / L, and the level of TG in the control group decreased to 2.20 鹵0.30 mmol / L, respectively. The difference was statistically significant (P 0.01). Conclusion 1. Jianpi Xiezhuo decoction can effectively improve the blood lipid level of hyperlipidemia patients with phlegm and turbid repression. Jianpi Xiezhuo decoction can obviously improve the syndrome of hyperlipidemia of phlegm and turbid repressor type.
【學(xué)位授予單位】:黑龍江中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R259

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