本文選題：多形性日光疹 + 火針　； 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：通過(guò)觀察火針治療多形性日光疹(肝郁血瘀證)的療效、復(fù)發(fā)情況及對(duì)患者生活質(zhì)量的影響,評(píng)價(jià)火針是否為治療本病證的一種方便、速效、安全、實(shí)用的中醫(yī)治法。方法：納入病例67例,隨機(jī)分成兩組,治療組35例,采用火針點(diǎn)刺肝俞、血海及局部皮損,對(duì)照組32例,予外用氟芬那酸丁酯軟膏。兩組療程均為三周。通過(guò)比較兩組患者治療前、治療第9天、治療后及隨訪時(shí)的皮損情況(皮損面積、丘疹、結(jié)節(jié)、苔蘚化、表皮剝脫)及自覺(jué)癥狀(瘙癢)的評(píng)分變化,于治療結(jié)束進(jìn)行近期療效評(píng)判,治療后2月進(jìn)行遠(yuǎn)期療效及復(fù)發(fā)的評(píng)判。應(yīng)用DLQI量表評(píng)價(jià)治療前后患者生活質(zhì)量的變化情況。所有資料用SPSS21.0進(jìn)行分析。結(jié)果：1、組內(nèi)比較：治療前后,兩組皮損總積分、各項(xiàng)積分及DLQI積分下降均有統(tǒng)計(jì)學(xué)差異(P0.01)；2、組間比較：(1)治療第9天,治療組皮損總積分較對(duì)照組有顯著性差異(P0.01)：結(jié)節(jié)、苔蘚化及瘙癢評(píng)分均優(yōu)于對(duì)照組(P0.05),其中瘙癢有顯著性差異(P0.01)；DLQI積分比較無(wú)統(tǒng)計(jì)學(xué)差異(P0.05)。(2)治療后,兩組近期療效、皮損總積分均無(wú)統(tǒng)計(jì)學(xué)差異(P0.05)：結(jié)節(jié)、苔蘚化及瘙癢評(píng)分均優(yōu)于對(duì)照組(P0.05),其中結(jié)節(jié)、瘙癢均有顯著性差異(P0.01);DLQI評(píng)分有統(tǒng)計(jì)學(xué)差異(P0.05)。(3)隨訪2月,治療組在遠(yuǎn)期療效、痊愈率及皮損總積分上均優(yōu)于對(duì)照組(P0.05)；DLQI積分有顯著差異(P0.01)；治療組復(fù)發(fā)率低于對(duì)照組(P0.05)。(4)兩組安全性及依從性均良好(P0.05)。結(jié)論：1、火針與氟芬那酸丁酯軟膏治療多形性日光疹(肝郁血瘀證)均有較好療效。2、火針治療起效快,對(duì)于結(jié)節(jié)、苔蘚化及瘙癢療效較好。3、火針治療多形性日光疹(肝郁血瘀證)遠(yuǎn)期療效、降低復(fù)發(fā)率及對(duì)患者生活質(zhì)量的提高等方面均優(yōu)于氟芬那酸丁酯軟膏。4、火針療法操作簡(jiǎn)便,快速有效,不良反應(yīng)少,安全性高,適合推廣使用。
[Abstract]:Objective: to evaluate whether fire acupuncture is a convenient, effective, safe and practical Chinese medicine method for the treatment of this syndrome by observing the curative effect, recurrence and the influence on the quality of life of patients with multiple sunspot rash (liver depression and blood stasis syndrome) by fire acupuncture. Methods: 67 cases were randomly divided into two groups: the treatment group (35 cases) was treated with fire needle needling Ganshu, Xuehai and local skin lesions, and the control group (32 cases) was treated with flufenac butyrate ointment. The course of treatment in both groups was three weeks. The scores of lesions (lesion area, papules, nodules, mossy, epidermis exfoliation) and conscious symptoms (pruritus) were compared between the two groups before, on the 9th day, after treatment and at follow-up. The short-term curative effect was evaluated at the end of treatment, and the long-term effect and recurrence were evaluated 2 months after treatment. The changes of quality of life (QOL) of patients before and after treatment were evaluated with DLQI scale. All data were analyzed by SPSS21.0. Results: before and after treatment, there were significant differences in the total score of skin lesion, the decrease of each score and DLQI score between the two groups (P < 0.01) and the comparison between the two groups on the 9th day of treatment (P < 0.01). The total score of skin lesion in the treatment group was significantly different from that in the control group (P < 0.01), and there was no significant difference between the treatment group and the control group (P < 0.01). The scores of moss and pruritus were better than those of the control group (P 0.05). There was no significant difference in DLQI score between the two groups after treatment. After treatment, there was no significant difference in the short-term curative effect and the total score of skin lesion between the two groups (P 0.05). The scores of moss and pruritus were better than those of the control group (P 0.05). There were significant differences in the scores of nodule and pruritus. There was a significant difference in DLQI score between the two groups. The recovery rate and the total score of skin lesion were significantly higher than that of the control group (P 0.05) and the recurrence rate of the treatment group was lower than that of the control group (P 0.05) and the compliance of the two groups was better than that of the control group (P 0.05). Conclusion both fire needle and flufenac butyrate ointment have good curative effect in treating pleomorphic sunlight rash (liver depression and blood stasis syndrome). The curative effect of mossy and pruritus was better. 3. The long term curative effect of fire acupuncture in the treatment of multiform sunlight rash (liver depression and blood stasis syndrome), reducing the recurrence rate and improving the quality of life of the patients were better than that of flufenac butyl ester ointment. 4. The fire acupuncture therapy was simple and convenient. It is fast and effective, less adverse reaction, high safety and suitable for popularization.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R246.7

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