本文選題：肛癰 + 保留灌腸　； 參考：《河南中醫(yī)藥大學》2016年碩士論文

【摘要】：目的：回顧采用熱毒清方治療肛癰(熱毒蘊結(jié)型),觀察總結(jié)其對肛癰(熱毒蘊結(jié)型)的臨床療效,及有無不良反應。并通過對治療藥物的現(xiàn)代藥理研究及治療方法的探討,初步探討其治療機制,為臨床上.的運用提供科學的依據(jù)。方法：選擇201 4年07月～2016年01月來自于鄭州市大腸肛門病醫(yī)院,符合肛癰(熱毒蘊結(jié)型)門診患者60例。由就診先后順序隨機的分為對照組30例(鹽酸左氧氟沙星注射液與奧硝唑氯化鈉注射液)抗生素靜脈滴注,治療組30例抗生素靜脈滴注(鹽酸左氧氟沙星注射液聯(lián)合奧硝唑氯化鈉注射液)聯(lián)合熱毒清方保留灌腸。7天為一療程,觀察兩組在治療前和治療7天后,患者肛門疼痛、腫塊范圍大小、全身情況、腫塊質(zhì)地、臨床總療效、不良反應情況。記錄治療過程中相關(guān)癥狀和體征的變化,并分析比較兩組患者在肛門部疼痛情況,肛門腫塊范圍大小的變化以及全身情況、腫塊質(zhì)地和臨床總療效及不良反應等方面的差異,最后數(shù)據(jù)的分析是采用統(tǒng)計學軟件SPSS19.0處理。結(jié)果：經(jīng)統(tǒng)計學分析,兩組患者在基本情況上具有可比性(P0.05)1.比較治療后兩組肛門疼痛情況,所得治療組優(yōu)于對照組,有顯著差異,(P0.05)具有統(tǒng)計學意義,表明熱毒清方能明顯減輕患者肛門部的疼痛。2.治療后兩組腫塊范圍大小變化情況對比,所得治療組優(yōu)于對照組,有顯著差異(P0.05),有統(tǒng)計學意義,表明熱毒清方能促進患者肛門部腫塊的消散吸收,范圍大者,可以縮小其范圍。3.治療后兩組全身情況方面比較,所得治療組優(yōu)于對照組,有顯著差異(P0.05),具有統(tǒng)計學意義,表明熱毒清方在改善患者全身情況方面療效顯著。4.治療后兩組腫塊質(zhì)地情況比較,所得治療組優(yōu)于對照組,有顯著差異(P0.05),具有統(tǒng)計學意義,表明熱毒清方可使腫塊軟化直至最后被消散。5.比較兩組治療后治愈情況,治療組治愈8例,對照組治愈2例,經(jīng)統(tǒng)計學分析有差異(P0.05),說明治療組治療效果明顯優(yōu)于對照組。6.兩組患者在治療前后均未出現(xiàn)任何不良反應情況。結(jié)論：抗生素聯(lián)合熱毒清方治療肛癰(熱毒蘊結(jié)型)療效肯定,能有效緩解患者肛門部疼痛,促進患者肛門部膿腫腫塊消散吸收,范圍大者則能縮小腫塊范圍,降低了炎癥刺激,并且沒有發(fā)現(xiàn)不良反應,安全可行,是治療肛癰(熱毒蘊結(jié)型)的有效方法。本研究治療肛癰(熱毒蘊結(jié)型),采用抗生素聯(lián)合中藥保留灌腸,是中西醫(yī)結(jié)合的充分體現(xiàn),不僅安全有效、價格便宜而且治療操作方便、無創(chuàng)傷,免除了手術(shù)帶來的痛苦,患者也比較接受。
[Abstract]:Objective: to review the clinical effect of Reduqing recipe in the treatment of anal carbuncle (heat toxin accumulation type), and to observe its clinical effect on anal carbuncle (heat toxin accumulation type) and whether it has adverse reactions. And through the modern pharmacological research and the treatment method of the treatment drugs, the treatment mechanism is preliminarily discussed, which is clinical. To provide scientific basis for the use of. Methods: a total of 60 outpatients with anal carbuncle (heat and toxin accumulation type) from July 2014 to January 2016 were selected from Zhengzhou large bowel and anal disease hospital. The patients were randomly divided into control group (levofloxacin hydrochloride injection and ornidazole sodium chloride injection). 30 patients in the treatment group were treated with antibiotic intravenous drip (levofloxacin hydrochloride injection combined with ornidazole sodium chloride injection) and retention enema for 7 days as a course of treatment. Anus pain was observed before treatment and 7 days after treatment. Mass size, systemic condition, mass texture, total clinical efficacy, adverse reactions. To record the changes of symptoms and signs in the course of treatment, and to analyze and compare the differences between the two groups in the anus pain, the size of the anal mass, the whole body, the texture of the mass, the clinical curative effect and the adverse reactions. The final data analysis is the use of statistical software SPSS19.0 processing. Results: by statistical analysis, the two groups of patients in the basic conditions can be comparable P 0.05 1. Compared with the two groups after the treatment of anal pain, the treatment group is superior to the control group, there is a significant difference (P0.05), indicating that RDQ can significantly reduce the pain of anal pain. 2. After treatment, the changes of the tumor range in the two groups were compared. The results showed that the treatment group was superior to the control group, and there was significant difference (P 0.05), which indicated that Reduqing prescription could promote the dissipation and absorption of the anal mass of the patients, and the range of the treatment group could be reduced by 3. 3. After treatment, compared with the control group, the treatment group is better than the control group, there is a significant difference (P 0.05), there is statistical significance, indicating that the effect of Reduqing prescription in improving the patients' whole body condition is significant. 4. After treatment, the texture of the tumor in the treatment group was better than that in the control group, and there was a significant difference between the treatment group and the control group (P 0.05), which indicated that RDQ could soften the mass until it was finally dissipated. There were 8 cases cured in the treatment group and 2 cases in the control group, which showed that the therapeutic effect of the treatment group was better than that of the control group. There were no adverse reactions in both groups before and after treatment. Conclusion: the treatment of anal carbuncle with antibiotics combined with Reduqing prescription is effective in relieving anal pain, promoting the dissipation and absorption of anal abscess, and reducing the area of the mass in large range. It is safe and feasible to treat anal carbuncle. In this study, the treatment of anal carbuncle (heat toxin accumulation knot type, antibiotics combined with traditional Chinese medicine retention enema) is a full embodiment of integrated Chinese and western medicine, which is not only safe and effective, cheap and easy to treat, but also has no trauma, and avoids the pain caused by the operation. Patients are also more receptive.
【學位授予單位】：河南中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R266

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