本文選題：反流性食管炎 + 寒熱錯(cuò)雜型��； 參考：《遼寧中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:運(yùn)用辛升苦降代表方半夏瀉心湯,聯(lián)合奧美拉唑腸溶膠囊、瑞巴派特治療寒熱錯(cuò)雜型反流性食管炎,觀察其治療的臨床療效,為中西醫(yī)結(jié)合治療胃食管反流病提供臨床依據(jù)。材料與方法:所選患者均出自2015年1月—2016年11月我院消化內(nèi)科門診患者,所有患者經(jīng)臨床診斷,均符合西醫(yī)診斷反流性食管炎,中醫(yī)辨證分型為寒熱錯(cuò)雜型的診斷標(biāo)準(zhǔn)的51例患者納入。將51例患者按照隨機(jī)數(shù)字表法分為治療組和對照組,治療組27例和對照組24例。對照組予常規(guī)西醫(yī)治療(包括西藥PPI制劑、黏膜保護(hù)劑),奧美拉唑腸溶膠囊40mg每日1次口服;瑞巴派特0.1g每日3次;治療組在西醫(yī)常規(guī)治療的基礎(chǔ)上加中藥湯劑100ml每日3次。中藥湯劑以辛升苦降之半夏瀉心湯為基礎(chǔ)方。兩組患者均連續(xù)治療4周,治療結(jié)束后分別對治療前、治療后2周、治療后4周的單項(xiàng)癥狀積分進(jìn)行分析比較,對兩組治療2周、4周后的改善率及總癥狀積分進(jìn)行比較,以及兩組治療總有效率進(jìn)行對比。結(jié)果:1.治療后單項(xiàng)癥狀積分比較,治療組優(yōu)于對照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05),且治療4周優(yōu)于治療2周。2.在改善患者主要臨床癥狀方面,治療組與對照組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療4周各癥狀積分改善率優(yōu)于治療2周改善率。兩組治療2周、4周后的總癥狀積分均低于治療前,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。3.治療組和對照組總有效率分別為96.30%和70.83%,治療組與對照組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:與單純西醫(yī)治療相比較,聯(lián)合使用半夏瀉心湯在改善寒熱錯(cuò)雜型反流性食管炎的臨床癥狀方面優(yōu)勢明顯,研究表明半夏瀉心湯能明顯改善患者的臨床癥狀,有較好的臨床療效。
[Abstract]:Objective: to treat reflux esophagitis with Xisheng Kujiang representative prescription Banxia Xiexin decoction combined with omeprazole enteric dissolution capsule and to observe its clinical effect. To provide clinical basis for the treatment of gastroesophageal reflux disease with integrated Chinese and western medicine. Materials and methods: all the patients were selected from the outpatient department of the Department of Digestive Medicine of our hospital from January 2015 to November 2016. All the patients were diagnosed as reflux esophagitis by Western medicine. TCM syndrome differentiation for the diagnosis of cold and heat mixed criteria of 51 patients included. 51 patients were divided into treatment group (n = 27) and control group (n = 24). The control group was treated with routine western medicine (including western medicine PPI preparation, mucosal protection agent, omeprazole enteric-coated capsule 40mg once a day; repapet 0.1g three times a day; treatment group plus traditional Chinese medicine decoction 100ml 3 times a day on the basis of western medicine routine treatment. Traditional Chinese medicine decoction is based on Banxia Xiexin decoction. The single symptom scores before treatment, 2 weeks after treatment and 4 weeks after treatment were analyzed and compared, and the improvement rate and total symptom score were compared between the two groups after 2 weeks and 4 weeks of treatment. The total effective rate was compared between the two groups. The result is 1: 1. After treatment, the single symptom score in the treatment group was better than that in the control group, the difference was statistically significant (P 0.05), and the treatment for 4 weeks was better than the treatment for 2 weeks. In improving the main clinical symptoms of the patients, the difference between the treatment group and the control group was statistically significant (P 0.05), and the improvement rate of each symptom score at 4 weeks was better than that of the control group at 2 weeks. After 2 weeks and 4 weeks of treatment, the total symptom score of the two groups was lower than that before treatment, and the difference was statistically significant (P 0.05. 3). The total effective rates of the treatment group and the control group were 96.30% and 70.83% respectively. The difference between the treatment group and the control group was statistically significant (P 0.05). Conclusion: compared with western medicine alone, Banxia Xiexin decoction combined with Banxia Xiexin decoction has obvious advantages in improving the clinical symptoms of reflux esophagitis of the type of cold and heat, and the research shows that Banxia Xiexin decoction can obviously improve the clinical symptoms of the patients. It has good clinical effect.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 陳超;焦艷;陶源;;氣滯胃痛顆粒聯(lián)合雷貝拉唑?qū)Ψ戳餍允彻苎孜?食管動(dòng)力及炎癥因子的影響[J];藥物評價(jià)研究;2017年01期

2 嚴(yán)湖;;單兆偉教授運(yùn)用半夏治療胃病經(jīng)驗(yàn)初探[J];環(huán)球中醫(yī)藥;2016年12期

3 王九裕;;氣滯胃痛顆粒與奧美拉唑聯(lián)合治療胃食管反流病的臨床觀察[J];中國中醫(yī)藥現(xiàn)代遠(yuǎn)程教育;2016年19期

4 鄧媛;王奇;;胃蘇顆粒對慢性胃炎患者血清炎癥因子及胃黏膜COX-2、E-cadherin表達(dá)的影響[J];中國中醫(yī)藥科技;2016年05期

5 鄭敏;唐艷萍;;柴胡疏肝散為主治療胃食管反流病的Meta分析[J];天津中醫(yī)藥;2016年08期

6 王文婷;張廠;王林恒;李軍祥;胡立明;孟捷;韓海嘯;王志斌;陳潤花;余軼群;趙薇巍;彭丹;;胃食管反流病中醫(yī)證候?qū)W研究探索[J];環(huán)球中醫(yī)藥;2016年08期

7 楊靖;楊艷;何李君;孔文霞;李培;張曉云;;李培教授治療非糜爛性胃食管反流病經(jīng)驗(yàn)[J];中醫(yī)藥信息;2016年02期

8 王冕;段俊峰;孫建峰;;治脊療法配合質(zhì)子泵抑制劑治療反流性食管炎的臨床研究[J];頸腰痛雜志;2015年05期

9 季艷華;;柴胡疏肝散治療反流性食管炎82例的療效觀察[J];中國醫(yī)藥科學(xué);2015年14期

10 孫鳳嬌;李振麟;錢士輝;濮社班;;干姜化學(xué)成分和藥理作用研究進(jìn)展[J];中國野生植物資源;2015年03期

相關(guān)會(huì)議論文 前1條

1 劉華一;魏景景;;胃食管反流病辨證分型及用藥規(guī)律的文獻(xiàn)研究[A];中華中醫(yī)藥學(xué)會(huì)第二十二屆全國脾胃病學(xué)術(shù)交流會(huì)暨2010年脾胃病診療新進(jìn)展學(xué)習(xí)班論文匯編[C];2010年

相關(guān)碩士學(xué)位論文 前2條

1 張炳輝;胃蘇顆粒聯(lián)合西醫(yī)常規(guī)用藥治療胃食管反流病的臨床研究[D];湖北中醫(yī)藥大學(xué);2013年

2 鐘昊燕;胃食管反流病中醫(yī)證候分布規(guī)律的初步研究[D];廣州中醫(yī)藥大學(xué);2007年

，

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