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不同病理狀態(tài)下日月穴定點超聲肝內(nèi)解剖結(jié)構(gòu)變化的比較研究

發(fā)布時間:2018-04-22 17:22

  本文選題:日月穴 + 經(jīng)穴特異性 ; 參考:《遼寧中醫(yī)藥大學(xué)》2017年碩士論文


【摘要】:目的:通過對肝臟內(nèi)部疾病組別、肝臟外部疾病、健康組的日月穴對應(yīng)的肝臟內(nèi)部解剖組織結(jié)構(gòu)的變異情況進行比較研究。從肝臟的解剖形態(tài)學(xué)和組織形態(tài)學(xué)角度探討膽經(jīng)經(jīng)穴、膽募日月反映病癥效應(yīng)的生物醫(yī)學(xué)基礎(chǔ),論證特定穴理論的科學(xué)性,為部分闡明中醫(yī)肝膽相表里理論的科學(xué)性提供研究依據(jù)。對象與方法:實驗對象:采集疾病組病例176例,其中肺結(jié)核患者70例、慢乙肝患者52例、肝硬化患者33例、脂肪肝患者21例,健康組44例。實驗方法:采用彩色多普勒超聲技術(shù),在受試者肝區(qū)日月穴實施定點低頻超聲垂直檢測,以彩超視野中心為原點,記錄距離原點最近的肝內(nèi)系統(tǒng)組織形態(tài),總結(jié)并匯總數(shù)據(jù)。分別進行肝臟內(nèi)部不同疾病、肝內(nèi)疾病與肝外疾病和健康對照組解剖組織結(jié)構(gòu)檢出率的組間配對檢驗。探討肝臟不同病理狀態(tài),膽募日月肝臟內(nèi)部解剖組織結(jié)構(gòu)變異規(guī)律,探討日月在肝臟疾病病理演變過程中,反應(yīng)病癥效應(yīng)的生物醫(yī)學(xué)基礎(chǔ)。本實驗數(shù)據(jù)采用SPSS17.0統(tǒng)計軟件進行統(tǒng)計分析處理,無序計數(shù)資料采用卡方檢驗,計量資料用均數(shù)±標(biāo)準(zhǔn)差((?)±s)表示,兩樣本均數(shù)比較采用獨立樣本t檢驗,不屬于正態(tài)分布和方差齊性的數(shù)據(jù)用非參數(shù)檢驗。統(tǒng)計檢驗結(jié)果P≤0.05為有統(tǒng)計學(xué)意義,P0.05為無統(tǒng)計學(xué)意義。結(jié)果:1.肝內(nèi)疾病組(慢乙肝、肝硬化、脂肪肝)門靜脈右干檢出率高于健康組,P0.05。提示:肝臟內(nèi)部解剖組織結(jié)構(gòu)的病理變化---慢乙肝特有的門靜脈系統(tǒng)的病理變化,是影響日月穴反映病癥效應(yīng)的因素之一。2.肝內(nèi)疾病組門靜脈右干檢出率高于肝外疾病肺結(jié)核組,P0.05;提示,日月穴下解剖組織結(jié)構(gòu)的變異具有針對肝臟病變的特異性。3.肺結(jié)核與健康對照組比較,P0.05。4.慢乙肝組、肝硬化組、脂肪肝組,組間配對檢驗均為,P0.05。提示日月穴下解剖組織結(jié)構(gòu)的變異5.膽囊的檢出率肝臟內(nèi)部疾病具有增高的趨勢,受試者工作特征曲線檢驗,ROCAUC50%。結(jié)論:1.日月穴下門靜脈右干和膽囊在肝臟疾病發(fā)展過程中的檢出率的變化是日月穴敏化的病理基礎(chǔ)。2.膽經(jīng)募穴日月變化規(guī)律符合中醫(yī)學(xué)肝膽相表里理論,具有判斷、揭示慢乙肝病理變化的應(yīng)用價值。
[Abstract]:Objective: to compare the variation of the anatomical structure of the internal liver disease group, the liver external disease group and the healthy group. From the angle of anatomical morphology and histomorphology of the liver, this paper discusses the biomedical basis of the acupoints of the gallbladder meridian and the day and the moon reflecting the disease, and proves the scientific nature of the theory of specific acupoints. It provides the research basis for explaining the scientific nature of the theory of liver and gallbladder in Chinese medicine. Objects and methods: 176 cases of disease were collected, including 70 cases of pulmonary tuberculosis, 52 cases of chronic hepatitis B, 33 cases of liver cirrhosis, 21 cases of fatty liver and 44 cases of healthy group. Methods: the technique of color Doppler ultrasound was used to carry out the vertical detection of low-frequency ultrasound at the point of Ri Yue in the liver area of the subjects. The center of the field of vision of color Doppler ultrasound was taken as the origin, and the tissue morphology of the liver system nearest to the origin was recorded, and the data were summarized and collected. The detectable rates of anatomical tissue structure of different diseases within the liver, intrahepatic diseases, extrahepatic diseases and healthy controls were tested by paired test. To study the variation of liver anatomical tissue structure in different pathological states of liver, and to explore the biomedical basis of reflecting the effect of liver disease in the pathological process of liver diseases. The data of this experiment are analyzed by SPSS17.0 software, the random counting data are chi-square test, the measurement data are expressed by mean 鹵standard deviation) 鹵s), and the comparison of the two samples' mean is carried out by independent sample t test. Data that do not belong to normal distribution and homogeneity of variance are tested by non-parametric test. The results of statistical test P 鈮,

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