本文選題：中醫(yī)傳承輔助系統(tǒng)　切入點：月經后期　出處：《山東中醫(yī)藥大學》2016年碩士論文　論文類型：學位論文

【摘要】：目的:本研究通過對古代中醫(yī)文獻中與月經后期相關的中藥、方劑,進行整理、總結、歸類,探尋月經后期的基本理論及臨床用藥規(guī)律,包括組方規(guī)律,藥物、藥對及用藥指征,并進行統(tǒng)計學分析,以期對月經后期及其引起的不孕癥的治療提供更好的思路和方法。方法:系統(tǒng)回顧古代中醫(yī)文獻,梳理出與月經后期有關的中藥、方劑,篩選出有效方劑藥物,建立月經后期方劑數據庫,初步分析古代醫(yī)家治療月經后期及其相關癥狀的臨床經驗和常用方藥。運用“中醫(yī)傳承輔助系統(tǒng)”,應用該軟件的集成規(guī)則分析,改進互信息法、復雜系統(tǒng)熵聚類及無監(jiān)督的熵層次聚類等數據挖掘方法[1],從整體上對月經后期的藥物使用規(guī)律及配伍規(guī)律進行相關性分析。結果:通過中醫(yī)傳承輔助系統(tǒng)對治療月經后期及其相關疾病的方劑進行藥物頻次、關聯規(guī)則和復雜系統(tǒng)熵聚類的分析,綜合結果可以得出其組方規(guī)律、常用藥物、藥對及用藥指征。通過對古代文獻中298首處方的分析,用藥范圍結果表明,共涉及215味中藥,補虛藥、活血化瘀藥、理氣藥、溫里藥、利水滲濕藥、化痰止咳平喘藥、清熱藥等七類藥物是月經后期最常用的藥類。藥物的四氣分析結果顯示:溫性藥物使用頻率最高;藥物五味分析結果顯示甘味、辛味、苦味藥物最常見;藥物歸經出現的頻率由高到低的次序是:肝經、脾經、心經、腎經、肺經。利用“組方規(guī)律分析”版塊,系統(tǒng)性分析常用藥物及藥對,并利用改進的互信息法進行藥物關聯性分析,形成34組常用藥對,核心組合24個,基于無監(jiān)督熵層次聚類法得出新方12個,并對新方中的核心藥物進行分析,為臨床臨證處理及藥物治療提供理論依據。結論:本研究通過建立月經后期方藥數據庫,利用中醫(yī)傳承輔助系統(tǒng)對方劑進行錄入、整理,從多方面、多角度進行分析,構建規(guī)范的證候、方藥體系,對臨床工作有重要指導意義,值得進一步推廣應用。
[Abstract]:Objective: through sorting, summarizing and classifying the traditional Chinese medicine and prescriptions related to the late menstrual period in ancient Chinese medicine literature, to explore the basic theory and clinical drug use law of the late menstrual period, including the law of prescription and medicine. In order to provide a better idea and method for the treatment of postmenstrual period and infertility caused by it, a systematic review of the ancient Chinese medicine literature was carried out to sort out the Chinese medicine and prescription related to the late menstrual period. Screening out effective prescription drugs, establishing a database of prescriptions for late menstruation, A preliminary analysis of the clinical experience and common prescriptions of ancient physicians in the treatment of late menstruation and its related symptoms. By using the "Chinese Medicine inheritance Assistance system" and the application of the integrated rule analysis of the software, the mutual information method was improved. The methods of data mining such as entropy clustering and unsupervised entropy hierarchical clustering in complex systems [1] were used to analyze the correlation of drug use and compatibility in the later period of menstruation as a whole. Results: the treatment was treated by traditional Chinese Medicine (TCM) inheriting auxiliary system. The prescriptions for late menstruation and related diseases were used frequently. The association rules and entropy cluster analysis of complex systems can be used to find out the rule of its composition, common drugs, drug pairs and indications of drug use. By analyzing 298 prescriptions in ancient literature, the range of drug use shows that 215 kinds of traditional Chinese medicines are involved. Seven kinds of drugs, such as tonifying deficiency medicine, promoting blood circulation and removing blood stasis, regulating qi, warming medicine, promoting water and infiltrating dampness, resolving phlegm and relieving cough and relieving asthma, and clearing away heat, are the most commonly used drugs in the later period of menstruation. The results of four-gas analysis of the drugs show that: the use frequency of warm drugs is the highest; The results of the five-flavor medicine analysis showed that sweet taste, Xin flavor and bitter medicine were the most common drugs, and the frequency of the drug meridian appeared from high to low: liver, spleen, heart, kidney and lung. The common drugs and their pairs were systematically analyzed, and the improved mutual information method was used to analyze the drug association. 34 groups of common drug pairs were formed, with 24 core combinations, and 12 new drugs were obtained based on unsupervised entropy hierarchical clustering method. And the core drugs in the new prescription are analyzed to provide the theoretical basis for clinical clinical treatment and drug treatment. Conclusion: this study through the establishment of menstrual late prescription database, the use of traditional Chinese medicine inheritance assistance system for prescription input, collation, It is of great significance for clinical work to analyze from many aspects and angles, and to construct the standard syndrome and prescription system, which is worthy of further popularizing and applying.
【學位授予單位】：山東中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R271.111

【參考文獻】

相關期刊論文 前10條

1 劉家貴;;針灸配合推拿治療月經后期舉隅[J];黑龍江中醫(yī)藥;2013年04期

2 徐春娟;何曉暉;陳榮;;中醫(yī)婦科學奠基者陳自明學術思想的現代研究[J];江西中醫(yī)學院學報;2012年06期

3 肖晶晶;朱穎;;中醫(yī)藥治療月經后期的研究進展[J];陜西中醫(yī)學院學報;2012年03期

4 盧笑暉;單崎瑋;;基于中醫(yī)傳承輔助系統(tǒng)分析盧尚嶺教授治療頭風病用藥經驗[J];中國實驗方劑學雜志;2012年09期

5 盧朋;李健;唐仕歡;陳建新;左曉晗;劉西;溫少欣;高一波;楊洪軍;;中醫(yī)傳承輔助系統(tǒng)軟件開發(fā)與應用[J];中國實驗方劑學雜志;2012年09期

6 于桂艷;黃可佳;;補腎法治療月經后期臨床體會[J];遼寧中醫(yī)藥大學學報;2011年06期

7 李雪琳;羅海燕;;八珍湯加味治療月經后期30例[J];實用中醫(yī)藥雜志;2011年04期

8 于國君;;中年婦女月經后期從肝辨治之淺見[J];航空航天醫(yī)學雜志;2011年03期

9 李雪琳;;自擬補腎養(yǎng)血調經湯治療月經后期40例[J];云南中醫(yī)中藥雜志;2011年03期

10 陳香梅;趙海生;;當歸芍藥散加味應用于月經后期肝郁氣結證體會[J];河南中醫(yī);2011年02期

相關碩士學位論文 前1條

1 周偉;中藥方劑核心藥物及其配伍規(guī)律挖掘[D];南京大學;2013年

，

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